Bromodomain and extraterminal inhibitors block the Epstein-Barr virus lytic cycle at two distinct steps

BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency

(2017) Horng-Shen Chen et al.   PLoS Pathogens

Epstein–Barr virus latency type and spontaneous reactivation predict lytic induction levels

(2016) An T. Phan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Brd4 acetyllysine-binding protein is involved in activation of polyomavirus JC

(2016) Hassen S. Wollebo et al.   JOURNAL OF NEUROVIROLOGY

An Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4

(2016) Ke Ren et al.   PLoS Pathogens

Bendamustine reactivates latent Epstein-Barr virus

(2015) Samantha G. Fernandez et al.   LEUKEMIA & LYMPHOMA

Epstein–Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expression

(2015) Sharada Ramasubramanyan et al.   NUCLEIC ACIDS RESEARCH

Thirty Years of HIV and AIDS: Future Challenges and Opportunities

(2013) Carl W. Dieffenbach et al.   ANNALS OF INTERNAL MEDICINE

Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma

(2013) Bjoern Chapuy et al.   CANCER CELL

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism

(2013) Daniela Boehm et al.   CELL CYCLE

Hsp90 Inhibitor 17-DMAG Decreases Expression of Conserved Herpesvirus Protein Kinases and Reduces Virus Production in Epstein-Barr Virus-Infected Cells

(2013) X. Sun et al.   JOURNAL OF VIROLOGY

Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors

(2013) B Tolani et al.   ONCOGENE

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

(2013) S. Picaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BET bromodomain inhibition as a novel strategy for reactivation of HIV-1

(2012) Camellia Banerjee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation

(2012) Zichong Li et al.   NUCLEIC ACIDS RESEARCH

Reactivation of Latent HIV-1 by Inhibition of BRD4

(2012) Jian Zhu et al.   Cell Reports

Occupancy of chromatin organizers in the Epstein–Barr virus genome

(2011) Meghan M. Holdorf et al.   VIROLOGY

RNA Polymerase II Stalling Promotes Nucleosome Occlusion and pTEFb Recruitment to Drive Immortalization by Epstein-Barr Virus

(2011) Richard D. Palermo et al.   PLoS Pathogens

Suppression of inflammation by a synthetic histone mimic

(2010) Edwige Nicodeme et al.   NATURE

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

Infectious Mononucleosis

(2010) Katherine Luzuriaga et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Lentivirus Production

(2009) Xiaoyin Wang et al.   Jove-Journal of Visualized Experiments

The EBNA1 Protein of Epstein-Barr Virus Functionally Interacts with Brd4

(2008) A. Lin et al.   JOURNAL OF VIROLOGY

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS