The Mcm2–7-interacting domain of human mini-chromosome maintenance 10 (Mcm10) protein is important for stable chromatin association and origin firing

Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase

(2017) Marko Lõoke et al.   GENES & DEVELOPMENT

Xenopus Mcm10 is a CDK-substrate required for replication fork stability

(2016) Gaganmeet Singh Chadha et al.   CELL CYCLE

Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation

(2016) Tom D Deegan et al.   EMBO JOURNAL

Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex

(2015) Max E. Douglas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulated eukaryotic DNA replication origin firing with purified proteins

(2015) Joseph T. P. Yeeles et al.   NATURE

Mcm10 coordinates the timely assembly and activation of the replication fork helicase

(2015) Patricia Perez-Arnaiz et al.   NUCLEIC ACIDS RESEARCH

Cell-Cycle-Regulated Interaction between Mcm10 and Double Hexameric Mcm2-7 Is Required for Helicase Splitting and Activation during S Phase

(2015) Yun Quan et al.   Cell Reports

The N-terminus of Mcm10 is important for interaction with the 9-1-1 clamp and in resistance to DNA damage

(2014) Robert C. Alver et al.   NUCLEIC ACIDS RESEARCH

The physical interaction of Mcm10 with Cdc45 modulates their DNA-binding properties

(2013) Roberta Di Perna et al.   BIOCHEMICAL JOURNAL

Human SIRT1 regulates DNA binding and stability of the Mcm10 DNA replication factor via deacetylation

(2013) Samuel T. Fatoba et al.   NUCLEIC ACIDS RESEARCH

Mcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil Domain

(2013) Wenyue Du et al.   PLoS One

Mcm10 Plays a Role in Functioning of the Eukaryotic Replicative DNA Helicase, Cdc45-Mcm-GINS

(2012) George Watase et al.   CURRENT BIOLOGY

Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components

(2012) Mai Kanke et al.   EMBO JOURNAL

Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation

(2012) Frederick van Deursen et al.   EMBO JOURNAL

Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

(2011) Ryan C. Heller et al.   CELL

Mcm10 interacts with Rad4/Cut5TopBP1 and its association with origins of DNA replication is dependent on Rad4/Cut5TopBP1

(2011) Mark Taylor et al.   DNA REPAIR

Eukaryotic Chromosome DNA Replication: Where, When, and How?

(2010) Hisao Masai et al.   Annual Review of Biochemistry

CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol  , and GINS in budding yeast

(2010) S. Muramatsu et al.   GENES & DEVELOPMENT

Multiple Functions for Drosophila Mcm10 Suggested Through Analysis of Two Mcm10 Mutant Alleles

(2010) J. Apger et al.   GENETICS

Solution NMR Structure of the C-terminal DNA Binding Domain of Mcm10 Reveals a Conserved MCM Motif

(2010) Patrick D. Robertson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins

(2010) Ivar Ilves et al.   MOLECULAR CELL

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

(2009) Xiaohua Xu et al.   EMBO JOURNAL

Novel DNA Binding Properties of the Mcm10 Protein from Saccharomyces cerevisiae

(2009) Shlomo Eisenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical Interactions between Mcm10, DNA, and DNA Polymerase α

(2009) Eric M. Warren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins

(2009) J.-S. Im et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

(2009) C. Evrin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA

(2008) Kazuto Sugimura et al.   JOURNAL OF CELL BIOLOGY

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication

(2008) Arkaitz Ibarra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for DNA Binding by Replication Initiator Mcm10

(2008) Eric M. Warren et al.   STRUCTURE