Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

(2017) Liam A. Hurst et al.   Nature Communications

Bone Morphogenetic Protein 9 Enhances Lipopolysaccharide-Induced Leukocyte Recruitment to the Vascular Endothelium

(2016) Sarah L. Appleby et al.   JOURNAL OF IMMUNOLOGY

Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells

(2016) Jan R. Kraehling et al.   Nature Communications

The Regulation of NF-κB Subunits by Phosphorylation

(2016) Frank Christian et al.   Cells

Increased plasma BMP-2 levels are associated with atherosclerosis burden and coronary calcification in type 2 diabetic patients

(2015) Ming Zhang et al.   Cardiovascular Diabetology

Monocyte trafficking across the vessel wall

(2015) Teresa Gerhardt et al.   CARDIOVASCULAR RESEARCH

Bone morphogenetic protein 6 and oxidized low-density lipoprotein synergistically recruit osteogenic differentiation in endothelial cells

(2015) Lai-Ming Yung et al.   CARDIOVASCULAR RESEARCH

Endothelial microparticles mediate inflammation-induced vascular calcification

(2015) Paula Buendía et al.   FASEB JOURNAL

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension

(2015) Lu Long et al.   NATURE MEDICINE

BMP9 and BMP10 are necessary for proper closure of the ductus arteriosus

(2015) Sandrine Levet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Vascular Endothelium and Human Diseases

(2014) Peramaiyan Rajendran et al.   International Journal of Biological Sciences

Potential Roles of Bone Morphogenetic Protein (BMP)-9 in Human Liver Diseases

(2014) Blanca Herrera et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Small Molecules Dorsomorphin and LDN-193189 Inhibit Myostatin/GDF8 Signaling and Promote Functional Myoblast Differentiation

(2014) Daniel Horbelt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF-β1, but Not Bone Morphogenetic Proteins, Activates Smad1/5 Pathway in Primary Human Macrophages and Induces Expression of Proatherogenic Genes

(2014) Dinara Nurgazieva et al.   JOURNAL OF IMMUNOLOGY

Transcript Analysis Reveals a Specific HOX Signature Associated with Positional Identity of Human Endothelial Cells

(2014) Mark Toshner et al.   PLoS One

BMP9 Mutations Cause a Vascular-Anomaly Syndrome with Phenotypic Overlap with Hereditary Hemorrhagic Telangiectasia

(2013) Whitney L. Wooderchak-Donahue et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Anti-Inflammatory and Antiatherogenic Role of BMP Receptor II in Endothelial Cells

(2013) Chan Woo Kim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation

(2013) S. Levet et al.   BLOOD

Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence

(2013) D. W. Laux et al.   DEVELOPMENT

Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development

(2013) Alisha Holtzhausen et al.   FASEB JOURNAL

Endothelial TNF Receptor 2 Induces IRF1 Transcription Factor-Dependent Interferon-β Autocrine Signaling to Promote Monocyte Recruitment

(2013) Deepak Venkatesh et al.   IMMUNITY

Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression

(2013) Y. Yoshimatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development

(2013) H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of Bone Morphogenetic Protein Signaling Reduces Vascular Calcification and Atherosclerosis

(2012) Matthias Derwall et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

BMP9 and BMP10 are critical for postnatal retinal vascular remodeling

(2012) N. Ricard et al.   BLOOD

Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration

(2012) E. Rossi et al.   BLOOD

Pharmacological Suppression of Hepcidin Increases Macrophage Cholesterol Efflux and Reduces Foam Cell Formation and Atherosclerosis

(2011) Omar Saeed et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II

(2011) V. J. Burton et al.   BLOOD

Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Inhibits Neutrophil Recruitment through an Interleukin-6-Dependent Mechanism: a New Paradigm for Viral Immune Evasion

(2011) L. M. Butler et al.   JOURNAL OF VIROLOGY

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

Paracrine Osteogenic Signals via Bone Morphogenetic Protein-2 Accelerate the Atherosclerotic Intimal Calcification In Vivo

(2010) Yusuke Nakagawa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Bone morphogenetic protein receptor II regulates pulmonary artery endothelial cell barrier function

(2010) V. J. Burton et al.   BLOOD

HIV gp120 induces endothelial dysfunction in tumour necrosis factor-α-activated porcine and human endothelial cells

(2010) Jun Jiang et al.   CARDIOVASCULAR RESEARCH

Bone morphogenetic protein 4 mediates myocardial ischemic injury through JNK-dependent signaling pathway

(2010) Alok S. Pachori et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Inflammatory cytokines in vascular dysfunction and vascular disease

(2009) Alexander H. Sprague et al.   BIOCHEMICAL PHARMACOLOGY

A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum

(2009) Blanca Herrera et al.   BMC CELL BIOLOGY

Bone Morphogenetic Protein (BMP) and Activin Type II Receptors Balance BMP9 Signals Mediated by Activin Receptor-like Kinase-1 in Human Pulmonary Artery Endothelial Cells

(2009) Paul D. Upton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells

(2008) Anna Csiszar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

High-Density Lipoproteins Affect Endothelial BMP-Signaling by Modulating Expression of the Activin-Like Kinase Receptor 1 and 2

(2008) Yucheng Yao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells

(2008) Xianwu Li et al.   ATHEROSCLEROSIS

Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

(2008) Gregory D. Cuny et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bone Morphogenetic Protein-9 Is a Circulating Vascular Quiescence Factor

(2008) Laurent David et al.   CIRCULATION RESEARCH