Carbon dioxide-dependent regulation of NF-κB family members RelB and p100 gives molecular insight into CO2-dependent immune regulation

Partial pressure of arterial carbon dioxide and survival to hospital discharge among patients requiring acute mechanical ventilation: A cohort study

(2017) Brian M. Fuller et al.   JOURNAL OF CRITICAL CARE

Respiratory gases and the regulation of transcription

(2016) Eoin P. Cummins et al.   EXPERIMENTAL PHYSIOLOGY

The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100

(2016) Amanda J. Fusco et al.   Science Signaling

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

(2016) Javier Rodriguez et al.   Cell Reports

The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100

(2016) Amanda J. Fusco et al.   Science Signaling

Effect of Therapeutic Hypercapnia on Inflammatory Responses to One-lung Ventilation in Lobectomy Patients

(2015) Wei Gao et al.   ANESTHESIOLOGY

Activation of apoptosis by caspase-3-dependent specific RelB cleavage in anticancer agent-treated cancer cells: Involvement of positive feedback mechanism

(2015) Mizuki Kuboki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High CO2Levels Cause Skeletal Muscle Atrophy via AMP-activated Kinase (AMPK), FoxO3a Protein, and Muscle-specific Ring Finger Protein 1 (MuRF1)

(2015) Ariel Jaitovich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypercapnic acidosis prolongs survival of skin allografts

(2015) Yuan-Sheng Tzeng et al.   JOURNAL OF SURGICAL RESEARCH

Effects of PaCO2 derangements on clinical outcomes after cerebral injury: A systematic review

(2015) Brian W. Roberts et al.   RESUSCITATION

SUMOylation Attenuates the Transcriptional Activity of the NF-κB Subunit RelB

(2014) Julia Leidner et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17

(2014) Gail Otulakowski et al.   JOURNAL OF PHYSIOLOGY-LONDON

Alterations in the Expression of the NF-κB Family Member RelB as a Novel Marker of Cardiovascular Outcomes during Acute Exacerbations of Chronic Obstructive Pulmonary Disease

(2014) Laura Labonté et al.   PLoS One

p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation

(2014) Zhihua Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypo- and hypercapnia predict mortality in oxygen-dependent chronic obstructive pulmonary disease: a population-based prospective study

(2014) Zainab Ahmadi et al.   RESPIRATORY RESEARCH

Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial

(2014) Thomas Köhnlein et al.   Lancet Respiratory Medicine

Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in MurinePseudomonasPneumonia

(2013) Khalilah L. Gates et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Carbon dioxide-sensing in organisms and its implications for human disease

(2013) Eoin P. Cummins et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RelB: an outlier in leukocyte biology

(2013) Patrick Millet et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The RelB subunit of NFκB acts as a negative regulator of circadian gene expression

(2012) Marina M. Bellet et al.   CELL CYCLE

Hypercapnic acidosis attenuates ventilation-induced lung injury by a nuclear factor-κB–dependent mechanism

(2012) Maya Contreras et al.   CRITICAL CARE MEDICINE

Celebrating 25 years of NF-κB research

(2012) Sankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

Hypercapnia Induces Cleavage and Nuclear Localization of RelB Protein, Giving Insight into CO2Sensing and Signaling

(2012) Kathryn M. Oliver et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees

(2012) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

Hypercapnia in acute illness: Sometimes good, sometimes not*

(2011) Gail Otulakowski et al.   CRITICAL CARE MEDICINE

Regulation of gene expression by carbon dioxide

(2011) Cormac T. Taylor et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glycogen synthase kinase-3β is a crucial mediator of signal-induced RelB degradation

(2011) M Neumann et al.   ONCOGENE

Malt1-dependent RelB cleavage promotes canonical NF- B activation in lymphocytes and lymphoma cell lines

(2011) S. Hailfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis

(2010) Joseph Costello et al.   CRITICAL CARE MEDICINE

Elevated CO2 selectively inhibits interleukin-6 and tumor necrosis factor expression and decreases phagocytosis in the macrophage

(2010) Naizhen Wang et al.   FASEB JOURNAL

Requiem Protein Links RelB/p52 and the Brm-type SWI/SNF Complex in a Noncanonical NF-κB Pathway

(2010) Toshio Tando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF- B Links CO2 Sensing to Innate Immunity and Inflammation in Mammalian Cells

(2010) E. P. Cummins et al.   JOURNAL OF IMMUNOLOGY

Carbon dioxide inhalation causes pulmonary inflammation

(2009) Mohammad Abolhassani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury*

(2009) Donall F. O’Croinin et al.   CRITICAL CARE MEDICINE

Elevated CO2 levels affect development, motility, and fertility and extend life span in Caenorhabditis elegans

(2009) K. Sharabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection

(2009) I. T. Helenius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma

(2009) S. Hailfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF- B dependent mechanism

(2009) D O'Toole et al.   THORAX

Identification of lysine residues critical for the transcriptional activity and polyubiquitination of the NF-κB family member RelB

(2008) Julia Leidner et al.   BIOCHEMICAL JOURNAL

Differential RelA- and RelB-dependent gene transcription in LTβR-stimulated mouse embryonic fibroblasts

(2008) Agnes Lovas et al.   BMC GENOMICS

The Aryl Hydrocarbon Receptor Attenuates Tobacco Smoke-induced Cyclooxygenase-2 and Prostaglandin Production in Lung Fibroblasts through Regulation of the NF-κB Family Member RelB

(2008) Carolyn J. Baglole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY