The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100

Stimulus-selective crosstalk via the NF-κB signaling system reinforces innate immune response to alleviate gut infection

(2015) Balaji Banoth et al.   eLife

Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100

(2014) C. E. Lee et al.   BLOOD

p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation

(2014) Zhihua Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noncanonical NF- B Signaling Is Limited by Classical NF- B Activity

(2014) C. M. Gray et al.   Science Signaling

Quantitative Dissection and Modeling of the NF-κB p100-p105 Module Reveals Interdependent Precursor Proteolysis

(2014) Zekiye Buket Yılmaz et al.   Cell Reports

A Pathway Switch Directs BAFF Signaling to Distinct NFκB Transcription Factors in Maturing and Proliferating B Cells

(2014) Jonathan V. Almaden et al.   Cell Reports

A Structural Basis for Selective Dimerization by NF-κB RelB

(2013) Don Vu et al.   JOURNAL OF MOLECULAR BIOLOGY

Downregulation of TRAF2 Mediates NIK-Induced Pancreatic Cancer Cell Proliferation and Tumorigenicity

(2013) Heike Döppler et al.   PLoS One

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways

(2012) Vincent F-S Shih et al.   NATURE IMMUNOLOGY

Cleavage of NIK by the API2-MALT1 Fusion Oncoprotein Leads to Noncanonical NF- B Activation

(2011) S. Rosebeck et al.   SCIENCE

Constitutive noncanonical NFκB signaling in pancreatic cancer cells

(2010) Catherine E. Wharry et al.   CANCER BIOLOGY & THERAPY

Negative Feedback in Noncanonical NF- B Signaling Modulates NIK Stability Through IKK -Mediated Phosphorylation

(2010) B. Razani et al.   Science Signaling

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

NIK is involved in constitutive activation of the alternative NF-κB pathway and proliferation of pancreatic cancer cells

(2009) Takashi Nishina et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Nfkb1 and Nfkb2 Proteins p105 and p100 Function as the Core of High-Molecular-Weight Heterogeneous Complexes

(2009) Olga V. Savinova et al.   MOLECULAR CELL

NF-κB p52:RelB heterodimer recognizes two classes of κB sites with two distinct modes

(2008) Amanda J Fusco et al.   EMBO REPORTS

Stabilization of RelB Requires Multidomain Interactions with p100/p52

(2008) Amanda J. Fusco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

(2008) Sivakumar Vallabhapurapu et al.   NATURE IMMUNOLOGY

Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

(2008) Brian J Zarnegar et al.   NATURE IMMUNOLOGY