Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A

Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells

(2016) Laura R. Rega et al.   KIDNEY INTERNATIONAL

Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses

(2016) Jing He et al.   MOLECULAR BIOLOGY OF THE CELL

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

(2015) Jaime L. Schneider et al.   AGING CELL

Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

(2015) G. Napolitano et al.   EMBO Molecular Medicine

Munc13-4 Is a Rab11-binding Protein That Regulates Rab11-positive Vesicle Trafficking and Docking at the Plasma Membrane

(2015) Jennifer L. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficient Chaperone-Mediated Autophagy in Liver Leads to Metabolic Dysregulation

(2014) Jaime L. Schneider et al.   Cell Metabolism

The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation

(2014) Marta Moskot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes

(2013) Jose A. Martina et al.   JOURNAL OF CELL BIOLOGY

Upregulation of the Rab27a-Dependent Trafficking and Secretory Mechanisms Improves Lysosomal Transport, Alleviates Endoplasmic Reticulum Stress, and Reduces Lysosome Overload in Cystinosis

(2013) J. L. Johnson et al.   MOLECULAR AND CELLULAR BIOLOGY

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

(2013) Jaime Anguiano et al.   Nature Chemical Biology

Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system

(2012) A. L. Ambrosio et al.   BLOOD

Distribution of cystinosin-LKG in human tissues

(2012) Anna Taranta et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase–activating protein Gem-interacting protein

(2012) Jennifer L. Johnson et al.   MOLECULAR BIOLOGY OF THE CELL

Hematopoietic Stem Cell Gene Therapy for the Multisystemic Lysosomal Storage Disorder Cystinosis

(2012) Frank Harrison et al.   MOLECULAR THERAPY

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

Chaperone-mediated autophagy: a unique way to enter the lysosome world

(2012) Susmita Kaushik et al.   TRENDS IN CELL BIOLOGY

Chaperone-mediated autophagy at a glance

(2011) S. Kaushik et al.   JOURNAL OF CELL SCIENCE

Cysteamine therapy: a treatment for cystinosis, not a cure

(2011) Stephanie Cherqui   KIDNEY INTERNATIONAL

Chaperone-Mediated Autophagy Is Required for Tumor Growth

(2011) M. Kon et al.   Science Translational Medicine

Chaperone-mediated autophagy: machinery, regulation and biological consequences

(2010) Wenming Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Renal phenotype of the cystinosis mouse model is dependent upon genetic background

(2009) N. Nevo et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Optically Resolving Individual Microtubules in Live Axons

(2009) Harsha V. Mudrakola et al.   STRUCTURE

Chaperone-mediated autophagy: selectivity pays off

(2009) Ana Maria Cuervo   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Three-Dimensional Super-Resolution Imaging by Stochastic Optical Reconstruction Microscopy

(2008) B. Huang et al.   SCIENCE