Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling

FGF9 and FGF18 in idiopathic pulmonary fibrosis promote survival and migration and inhibit myofibroblast differentiation of human lung fibroblasts in vitro

(2016) Audrey Joannes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Novel Mechanisms for the Antifibrotic Action of Nintedanib

(2016) Sunad Rangarajan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody

(2016) Yongjun Yin et al.   Disease Models & Mechanisms

Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis

(2016) Chiko Shimbori et al.   JOURNAL OF PATHOLOGY

Mesenchymal Deficiency of Notch1 Attenuates Bleomycin-Induced Pulmonary Fibrosis

(2015) Biao Hu et al.   AMERICAN JOURNAL OF PATHOLOGY

Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair

(2015) BreAnne MacKenzie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Reemergence of Hedgehog Mediates Epithelial–Mesenchymal Crosstalk in Pulmonary Fibrosis

(2015) Biao Hu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Fibroblast Growth Factor 2 Is Required for Epithelial Recovery, but Not for Pulmonary Fibrosis, in Response to Bleomycin

(2015) Robert D. Guzy et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Loss of PTEN expression by mouse fibroblasts results in lung fibrosis through a CCN2-dependent mechanism

(2015) Sunil K. Parapuram et al.   MATRIX BIOLOGY

The Fibroblast Growth Factor signaling pathway

(2015) David M. Ornitz et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis

(2015) Tianju Liu et al.   PLoS One

Characterization of the cell of origin and propagation potential of the fibroblast growth factor 9-induced mouse model of lung adenocarcinoma

(2014) Daisuke Arai et al.   JOURNAL OF PATHOLOGY

A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

(2014) Talmadge E. King et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

(2014) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Qualitative Rather than Quantitative Changes Are Hallmarks of Fibroblasts in Bleomycin-Induced Pulmonary Fibrosis

(2013) Tatsuya Tsukui et al.   AMERICAN JOURNAL OF PATHOLOGY

Future Directions in Idiopathic Pulmonary Fibrosis Research. An NHLBI Workshop Report

(2013) Timothy S. Blackwell et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rapid Induction of Lung Adenocarcinoma by Fibroblast Growth Factor 9 Signaling through FGF Receptor 3

(2013) Y. Yin et al.   CANCER RESEARCH

Expression of Fibroblast Growth Factor 9 in Normal Human Lung and Idiopathic Pulmonary Fibrosis

(2013) Emily Coffey et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

(2013) Bi-Sen Ding et al.   NATURE

Mesenchymal-Specific Deletion of C/EBPβ Suppresses Pulmonary Fibrosis

(2012) Biao Hu et al.   AMERICAN JOURNAL OF PATHOLOGY

Mutant Soluble Ectodomain of Fibroblast Growth Factor Receptor-2 IIIc Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice

(2012) Zhi-hong Yu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Angiogenesis in Pulmonary Fibrosis

(2012) Chandru Hanumegowda et al.   CHEST

TGF-beta 1 induced fibroblast proliferation is mediated by the FGF-2/ERK pathway

(2012) Li Xiao   Frontiers in Bioscience-Landmark

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(2012) Wang Ju et al.   MOLECULAR MEDICINE

NP603, a novel and potent inhibitor of FGFR1 tyrosine kinase, inhibits hepatic stellate cell proliferation and ameliorates hepatic fibrosis in rats

(2011) Nan Lin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Modeling pulmonary fibrosis with bleomycin

(2011) Marios A. Mouratis et al.   CURRENT OPINION IN PULMONARY MEDICINE

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

Fibroblast Growth Factor Receptors Control Epithelial–Mesenchymal Interactions Necessary for Alveolar Elastogenesis

(2010) Sorachai Srisuma et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Essential Role for Resident Fibroblasts in Experimental Lung Fibrosis Is Defined by Lineage-Specific Deletion of High-Affinity Type II Transforming Growth Factor β Receptor

(2010) Rachel K. Hoyles et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Overexpression of Fibroblast Growth Factor-10 during Both Inflammatory and Fibrotic Phases Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice

(2009) Varsha V. Gupte et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Animal models of acute lung injury

(2008) Gustavo Matute-Bello et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Antifibrotic action of pirfenidone and prednisolone: Different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis

(2008) Hisashi Oku et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Murine models of pulmonary fibrosis

(2007) Bethany B. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The bleomycin animal model: A useful tool to investigate treatment options for idiopathic pulmonary fibrosis?

(2007) Antje Moeller et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Peplomycin, a bleomycin derivative, induces myofibroblasts in pulmonary fibrosis

(2004) Tokio Osaki et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY