Chemical signaling between gut microbiota and host chromatin: What is your gut really saying?

Iron Deprivation Induces Transcriptional Regulation of Mitochondrial Biogenesis

(2016) Jarred W. Rensvold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues

(2016) Kimberly A. Krautkramer et al.   MOLECULAR CELL

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

(2016) Marco Sciacovelli et al.   NATURE

Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

(2016) Rachel J. Perry et al.   NATURE

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

Diet-induced extinctions in the gut microbiota compound over generations

(2016) Erica D. Sonnenburg et al.   NATURE

The role of the gut microbiota in NAFLD

(2016) Christopher Leung et al.   Nature Reviews Gastroenterology & Hepatology

Antibiotic use and its consequences for the normal microbiome

(2016) Martin J. Blaser   SCIENCE

Biosensor reveals multiple sources for mitochondrial NAD+

(2016) X. A. Cambronne et al.   SCIENCE

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability

(2016) Moran Yassour et al.   Science Translational Medicine

Antibiotics, birth mode, and diet shape microbiome maturation during early life

(2016) Nicholas A. Bokulich et al.   Science Translational Medicine

Metabolic Regulation of Histone Post-Translational Modifications

(2015) Jing Fan et al.   ACS Chemical Biology

Diet Dominates Host Genotype in Shaping the Murine Gut Microbiota

(2015) Rachel N. Carmody et al.   Cell Host & Microbe

Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

(2015) Robert Caesar et al.   Cell Metabolism

Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome

(2015) Siegfried Ussar et al.   Cell Metabolism

The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: A review

(2015) F. Vahid et al.   GENE

Marked seasonal variation in the wild mouse gut microbiota

(2015) Corinne F Maurice et al.   ISME Journal

The microbiota in inflammatory bowel disease

(2015) Donal Sheehan et al.   JOURNAL OF GASTROENTEROLOGY

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Feeding the brain and nurturing the mind: Linking nutrition and the gut microbiota to brain development

(2015) Manu S. Goyal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

(2015) Kymberleigh A. Romano et al.   mBio

Comprehensive Catalog of Currently Documented Histone Modifications

(2015) Yingming Zhao et al.   Cold Spring Harbor Perspectives in Biology

The relationship between early-life environment, the epigenome and the microbiota

(2015) Amber V Majnik et al.   Epigenomics

Structural biology-based insights into combinatorial readout and crosstalk among epigenetic marks

(2014) Jiamu Du et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

(2014) Gopinath Sutendra et al.   CELL

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells

(2014) Antoaneta Belcheva et al.   CELL

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences

(2014) Laura M. Cox et al.   CELL

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Bile acids and the gut microbiome

(2014) Jason M. Ridlon et al.   CURRENT OPINION IN GASTROENTEROLOGY

Activation and Repression of Epstein-Barr Virus and Kaposi's Sarcoma-Associated Herpesvirus Lytic Cycles by Short- and Medium-Chain Fatty Acids

(2014) Kelly L. Gorres et al.   JOURNAL OF VIROLOGY

Artificial sweeteners induce glucose intolerance by altering the gut microbiota

(2014) Jotham Suez et al.   NATURE

Role of the Lower and Upper Intestine in the Production and Absorption of Gut Microbiota-Derived PUFA Metabolites

(2014) Céline Druart et al.   PLoS One

Effects of Sulforaphane and 3,3′-Diindolylmethane on Genome-Wide Promoter Methylation in Normal Prostate Epithelial Cells and Prostate Cancer Cells

(2014) Carmen P. Wong et al.   PLoS One

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis

(2014) S. A. Andrabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism

(2014) E. J. Radford et al.   SCIENCE

Differential Modulation by Akkermansia muciniphila and Faecalibacterium prausnitzii of Host Peripheral Lipid Metabolism and Histone Acetylation in Mouse Gut Organoids

(2014) S. Lukovac et al.   mBio

Maternal nutrition at conception modulates DNA methylation of human metastable epialleles

(2014) Paula Dominguez-Salas et al.   Nature Communications

A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner

(2014) D. R. Donohoe et al.   Cancer Discovery

Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities

(2013) Amos A Fatokun et al.   BRITISH JOURNAL OF PHARMACOLOGY

SDH Mutations Establish a Hypermethylator Phenotype in Paraganglioma

(2013) Eric Letouzé et al.   CANCER CELL

Influence of Metabolism on Epigenetics and Disease

(2013) William G. Kaelin et al.   CELL

Chromatin: Receiver and Quarterback for Cellular Signals

(2013) David G. Johnson et al.   CELL

Nutritional Control of Epigenetic Processes in Yeast and Human Cells

(2013) Meru J. Sadhu et al.   GENETICS

High-fat diet alters gut microbiota physiology in mice

(2013) Hannelore Daniel et al.   ISME Journal

Time Course Production of Urolithins from Ellagic Acid by Human Gut Microbiota

(2013) Rocío García-Villalba et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Quantitative Dynamics of the Link between Cellular Metabolism and Histone Acetylation

(2013) Adam G. Evertts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins

(2013) Jessica L. Feldman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

Dietary intervention impact on gut microbial gene richness

(2013) Aurélie Cotillard et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Phenethylisothiocyanate Alters Site- and Promoter-Specific Histone Tail Modifications in Cancer Cells

(2013) Yi Liu et al.   PLoS One

Kinetic Analysis of Iron-Dependent Histone Demethylases: α-Ketoglutarate Substrate Inhibition and Potential Relevance to the Regulation of Histone Demethylation in Cancer Cells

(2012) Barbara Cascella et al.   BIOCHEMISTRY

Inhibition of  -KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

(2012) M. Xiao et al.   GENES & DEVELOPMENT

Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation

(2012) Olivia S. Anderson et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation

(2012) Dallas R. Donohoe et al.   MOLECULAR CELL

Histone Acetylation Regulates Intracellular pH

(2012) Matthew A. McBrian et al.   MOLECULAR CELL

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

(2012) Suzanne Devkota et al.   NATURE

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression

(2012) Tom Latham et al.   NUCLEIC ACIDS RESEARCH

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Symptomatic atherosclerosis is associated with an altered gut metagenome

(2012) Fredrik H. Karlsson et al.   Nature Communications

The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols

(2011) Arumugam Rajavelu et al.   BMC BIOCHEMISTRY

(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells

(2011) V. Nandakumar et al.   CARCINOGENESIS

Epigenetic modulation of mechanisms involved in inflammation: Influence of selected polyphenolic substances on histone acetylation state

(2011) Anna K. Kiss et al.   FOOD CHEMISTRY

Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes

(2011) Ling Cai et al.   MOLECULAR CELL

DNA-binding factors shape the mouse methylome at distal regulatory regions

(2011) Michael B. Stadler et al.   NATURE

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase

(2010) X. Zhou et al.   CANCER RESEARCH

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

Quantification of Folic Acid in Human Feces After Administration of Bifidobacterium Probiotic Strains

(2010) G. Paolo Strozzi et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Folate is absorbed across the colon of adults: evidence from cecal infusion of 13C-labeled [6S]-5-formyltetrahydrofolic acid

(2009) Susanne Aufreiter et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells

(2009) Manjari Dimri et al.   CARCINOGENESIS

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon

(2008) Markus Waldecker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Evolution of Mammals and Their Gut Microbes

(2008) R. E. Ley et al.   SCIENCE