Allostery modulates the beat rate of a cardiac pacemaker

Free energy landscape remodeling of the cardiac pacemaker channel explains the molecular basis of familial sinus bradycardia

(2017) Stephen Boulton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Allostery without a conformational change? Revisiting the paradigm

(2015) Ruth Nussinov et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Pacemaker Activity of the Human Sinoatrial Node: An Update on the Effects of Mutations in HCN4 on the Hyperpolarization-Activated Current

(2015) Arie Verkerk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure and Energetics of Allosteric Regulation of HCN2 Ion Channels by Cyclic Nucleotides

(2015) Hannah A. DeBerg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP

(2014) Madoka Akimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Funny channel gene mutations associated with arrhythmias

(2013) Dario DiFrancesco   JOURNAL OF PHYSIOLOGY-LONDON

Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel

(2012) Xinping Xu et al.   STRUCTURE