Advances in cobalt complexes as anticancer agents

Synthesis and characterization of redox non-innocent cobalt(III) complexes of a O,N,O donor ligand: Radical generation, semi-conductivity, antibacterial and anticancer activities

(2015) Pritam Ghosh et al.   INORGANICA CHIMICA ACTA

2,6-Bis(2,6-diethylphenyliminomethyl)pyridine coordination compounds with cobalt(II), nickel(II), copper(II), and zinc(II): synthesis, spectroscopic characterization, X-ray study and in vitro cytotoxicity

(2015) Pablo Martinez-Bulit et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthesis, structure, and pharmacological evaluation of Co(III) complex containing tridentate Schiff base ligand

(2015) S. Jone Kirubavathy et al.   RUSSIAN JOURNAL OF COORDINATION CHEMISTRY

Ferrocenyl and dicobalt hexacarbonyl chromones – New organometallics inducing oxidative stress and arresting human cancer cells in G2/M phase

(2014) Konrad Kowalski et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cross-Bridged Cyclen or Cyclam Co(III) Complexes Containing Cytotoxic Ligands as Hypoxia-Activated Prodrugs

(2013) John Yu-Chih Chang et al.   INORGANIC CHEMISTRY

Water-Soluble Co(III) Complexes of Substituted Phenanthrolines with Cell Selective Anticancer Activity

(2013) Sivaraman Jagadeesan et al.   INORGANIC CHEMISTRY

Synthesis and spectral characterization of Schiff base complexes of Cu(II), Co(II), Zn(II) and VO(IV) containing 4-(4-aminophenyl)morpholine derivatives: Antimicrobial evaluation and anticancer studies

(2013) K. Dhahagani et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Delivery and release of curcumin by a hypoxia-activated cobalt chaperone: a XANES and FLIM study

(2013) Anna K. Renfrew et al.   Chemical Science

Redox activation of metal-based prodrugs as a strategy for drug delivery

(2012) Nora Graf et al.   ADVANCED DRUG DELIVERY REVIEWS

Tumour Hypoxia Affects the Responsiveness of Cancer Cells to Chemotherapy and Promotes Cancer Progression

(2012) Jean-Philippe Cosse et al.   Anti-Cancer Agents in Medicinal Chemistry

Titanium and Vanadium Complexes as Anticancer Agents

(2012) Irena Kostova   Anti-Cancer Agents in Medicinal Chemistry

Cobalt derivatives as promising therapeutic agents

(2012) Marie C Heffern et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Cobalt complexes with tripodal ligands: implications for the design of drug chaperones

(2012) Paul D. Bonnitcha et al.   DALTON TRANSACTIONS

A novel water soluble ligand bridged cobalt(ii) coordination polymer of 2-oxo-1,2-dihydroquinoline-3-carbaldehyde (isonicotinic) hydrazone: evaluation of the DNA binding, protein interaction, radical scavenging and anticancer activity

(2012) Duraisamy Senthil Raja et al.   DALTON TRANSACTIONS

Gallium-containing anticancer compounds

(2012) Christopher R Chitambar   Future Medicinal Chemistry

Dual Targeting of Hypoxic and Acidic Tumor Environments with a Cobalt(III) Chaperone Complex

(2012) Natsuho Yamamoto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Specific Inhibition of the Transcription Factor Ci by a Cobalt(III) Schiff Base–DNA Conjugate

(2012) Ryan R. Hurtado et al.   MOLECULAR PHARMACEUTICS

Targeted Inactivation of Snail Family EMT Regulatory Factors by a Co(III)-Ebox Conjugate

(2012) Allison S. Harney et al.   PLoS One

Cytotoxic Property of Surfactant-Cobalt(III) Complexes on a Human Breast Cancer Cell Line

(2011) Rajendran Senthil Kumar et al.   ARCHIV DER PHARMAZIE

Antifungal activity of α-methyl trans cinnamaldehyde, its ligand and metal complexes: promising growth and ergosterol inhibitors

(2011) Sheikh Shreaz et al.   BIOMETALS

N-alkylated cyclen cobalt(III) complexes of 1-(chloromethyl)-3-(5,6,7-trimethoxyindol-2-ylcarbonyl)-2,3-dihydro-1H-pyrrolo[3,2-f]quinolin-5-ol DNA alkylating agent as hypoxia-activated prodrugs

(2011) Guo-Liang Lu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs

(2011) Alberta Bergamo et al.   DALTON TRANSACTIONS

17 e−rhenium dicarbonyl CO-releasing molecules on a cobalamin scaffold for biological application

(2011) Fabio Zobi et al.   DALTON TRANSACTIONS

Cobalt(II) complexes with non-steroidal anti-inflammatory drug tolfenamic acid: Structure and biological evaluation

(2011) Sofia Tsiliou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Approaching tumour therapy beyond platinum drugs

(2011) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Biological evaluation of cobalt(II) complexes with non-steroidal anti-inflammatory drug naproxen

(2011) Filitsa Dimiza et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Synthesis, crystal structure, electrochemistry and studies on protein binding, antioxidant and biocidal activities of Ni(II) and Co(II) hydrazone complexes

(2011) P. Sathyadevi et al.   POLYHEDRON

Visualising the hypoxia selectivity of cobalt(iii) prodrugs

(2011) Byung J. Kim et al.   Chemical Science

Syntheses of 8-quinolinolatocobalt(iii) complexes containing cyclen based auxiliary ligands as models for hypoxia-activated prodrugs

(2010) John Yu-Chih Chang et al.   DALTON TRANSACTIONS

Biological evaluation of non-steroidal anti-inflammatory drugs-cobalt(ii) complexes

(2010) Filitsa Dimiza et al.   DALTON TRANSACTIONS

Chitosan–cobalt(II) and nickel(II) chelates as antibacterial agents

(2010) S. Adewuyi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Vitamin B12 as a carrier for targeted platinum delivery: in vitro cytotoxicity and mechanistic studies

(2010) Pilar Ruiz-Sánchez et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Synthesis and Biological Activities of Transition Metal Complexes Based on Acetylsalicylic Acid as Neo-Anticancer Agents

(2010) Gerhard Rubner et al.   JOURNAL OF MEDICINAL CHEMISTRY

In vitro bacteriostatic and DNA interaction studies of drug-based mixed-ligand complexes of cobalt(II)

(2010) Mohan Patel et al.   MEDICINAL CHEMISTRY RESEARCH

Modulation of the Biological Properties of Aspirin by Formation of a Bioorganometallic Derivative

(2009) Ingo Ott et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

On the medicinal chemistry of gold complexes as anticancer drugs

(2009) Ingo Ott   COORDINATION CHEMISTRY REVIEWS

Anti-tumor effects of nitrosylcobalamin against spontaneous tumors in dogs

(2009) Joseph A. Bauer et al.   INVESTIGATIONAL NEW DRUGS

Synthesis and Evaluation of Stable Bidentate Transition Metal Complexes of 1-(Chloromethyl)-5-hydroxy-3-(5,6,7-trimethoxyindol-2-ylcarbonyl)-2,3-dihydro-1H-pyrrolo[3,2-f]quinoline (seco-6-azaCBI-TMI) as Hypoxia Selective Cytotoxins

(2009) Jared B. J. Milbank et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of transcription by platinum antitumor compounds

(2009) Ryan C. Todd et al.   Metallomics

Platinum neurotoxicity pharmacogenetics

(2009) S. R. McWhinney et al.   MOLECULAR CANCER THERAPEUTICS

Targeted inhibition of Snail family zinc finger transcription factors by oligonucleotide-Co(III) Schiff base conjugate

(2009) A. S. Harney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis, micellar properties, DNA binding and antimicrobial studies of some surfactant–cobalt(III) complexes

(2008) R. Senthil Kumar et al.   BIOPHYSICAL CHEMISTRY

Cellular uptake and distribution of cobalt complexes of fluorescent ligands

(2008) Natsuho Yamamoto et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Surfactant–cobalt(III) complexes: Synthesis, critical micelle concentration (CMC) determination, DNA binding, antimicrobial and cytotoxicity studies

(2008) R KUMAR et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Design of anticancer prodrugs for reductive activation

(2008) Yu Chen et al.   MEDICINAL RESEARCH REVIEWS

Synthesis and cytotoxicity of a cobaltcarbonyl–alkyne enkephalin bioconjugate

(2007) Merja A. Neukamm et al.   CHEMICAL COMMUNICATIONS

Metallo-nucleosides: synthesis and biological evaluation of hexacarbonyl dicobalt 5-alkynyl-2′-deoxyuridines

(2007) Craig D. Sergeant et al.   ORGANIC & BIOMOLECULAR CHEMISTRY