Article
Biochemistry & Molecular Biology
Rudy Kurniawan, Fahrul Nurkolis, Nurpudji Astuti Taslim, Dionysius Subali, Reggie Surya, William Ben Gunawan, Darmawan Alisaputra, Nelly Mayulu, Netty Salindeho, Bonglee Kim
Summary: This study aimed to investigate the carotenoid profile and biological activities of Caulerpa racemosa. The results showed that the detected carotenoids were mainly xanthophylls, including beta-carotene, lutein, astaxanthin, canthaxanthin, zeaxanthin, beta-cryptoxanthin, and fucoxanthin. The carotenoid extract of C. racemosa exhibited significant antidiabetic, anti-obesity, anti-oxidative, anti-inflammatory, and cytotoxic activities, making it a potential candidate for drug development or functional food.
Article
Chemistry, Medicinal
Meng-Chou Lee, Han-Yang Yeh, Wen-Ling Shih
Summary: The study found that polysaccharides from Caulerpa microphysa extract have a high yield and specific composition, exhibiting anti-allergic, wound-healing, transdermal delivery, and moisturizing effects, suitable for cosmetic development.
Article
Chemistry, Applied
Meijia He, Jiejie Hao, Changning Feng, Yajing Yang, Zhuling Shao, Lei Wang, Wenjun Mao
Summary: OHSS2, a polysaccharide derived from green alga Cladophora oligoclada, possesses strong anti-diabetic activity by protecting mitochondria from hIAPP aggregation-induced damage and regulating mitochondrial function.
CARBOHYDRATE POLYMERS
(2022)
Review
Biotechnology & Applied Microbiology
Yongzhou Chi, Peng Wang
Summary: The genus Caulerpa is an economically significant green seaweed with potential uses in the nutraceutical, pharmaceutical, and cosmetic industries. Sulfated polysaccharides from Caulerpa have demonstrated a range of biological activities, including immunomodulation, anti-inflammatory, antinociceptive, antiviral, antibacterial, and anti-obesity effects. This paper provides a systematic review of the extraction, purification, structural characteristics, and biological activities of these sulfated polysaccharides, highlighting the need for further research on large-scale preparation, precise structural determination, and understanding of the structural basis for their bioactivity.
JOURNAL OF APPLIED PHYCOLOGY
(2023)
Article
Multidisciplinary Sciences
Happy Kurnia Permatasari, Fahrul Nurkolis, Piko Satria Augusta, Nelly Mayulu, Mury Kuswari, Nurpudji Astuti Taslim, Defny Silvia Wewengkang, Siti Chairiyah Batubara, William Ben Gunawan
Summary: This study investigated the effects of kombucha tea from seagrapes on blood glucose levels, total cholesterol, and PGC-1 alpha in Swiss albino mice. The study also found anti-glycation, tyrosinase inhibitory, and alpha-glucosidase inhibitory activities. Group C showed better potential for increasing PGC-1-alpha serum levels in mice.
Article
Nutrition & Dietetics
Happy Kurnia Permatasari, Fahrul Nurkolis, Hardinsyah Hardinsyah, Nurpudji Astuti Taslim, Nindy Sabrina, Faisal Maulana Ibrahim, Jodi Visnu, Dian Aruni Kumalawati, Sri Awalia Febriana, Toto Sudargo, Melvin Junior Tanner, Isma Kurniatanty, Vincentius Mario Yusuf, Ronald Rompies, Muhammad Rahimi Bahar, Holipah Holipah, Nelly Mayulu
Summary: Obesity is linked to accelerated aging and hinders healthy aging. This study evaluated compounds from sea grape extract for their potential anti-obesity properties and observed their effects on obesity parameters in the human body. The results showed that sea grape extract has significant anti-obesity and anti-aging effects.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Multidisciplinary
Wenqin Gao, Zhaolei Wang, Guoying Tan, Wei Liu, Marshet Getaye Sendeku, Ying Tang, Yun Kuang, Xiaoming Sun
Summary: TiO2 is a typical anti-ultraviolet agent in sunscreen cream, but lacks antioxidant activity. In this study, titanium hydride particles with dual functions of anti-oxidant and anti-ultraviolet are introduced. It shows great potential to eliminate hydroxyl radicals and enhances sun protection. This makes titanium hydride a promising and safe ingredient for sunscreen cream.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Environmental Sciences
Yi-Hui Su, Jia-Shuan Wu, Yan-Zhen Dai, Yng-Tay Chen, Yan-Xiu Lin, Yew-Min Tzeng, Jiunn-Wang Liao
Summary: This study evaluated the antioxidant activity, genotoxicity, and oral toxicity of Antrocin. The results showed that Antrocin has strong antioxidant activity and is not genotoxic. In addition, it did not produce any toxic effects in rats at a dose of 37.5 mg/kg. Therefore, Antrocin can be considered as a reference dose for therapeutic agents in humans.
Article
Food Science & Technology
Divyasree Arepally, Ravula Sudharshan Reddy, Ranil Coorey, Tridib Kumar Goswami
Summary: Consumer demand for healthy snacks is increasing, and millet is believed to have health benefits and can be used in the treatment of celiac disease and gastrointestinal problems. This study investigated the use of multi-millet flour (MMF) in making biscuits and found that increasing the proportion of MMF increased the water holding and oil absorption capacity of the biscuits. Biscuits made with MMF also had higher levels of fat, ash, fiber, total phenolic content, and antioxidant activity compared to wheat flour-based biscuits. Sensory analysis revealed that biscuits with 40% MMF were the most acceptable.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Oncology
Happy Kurnia Permatasari, Defny Silvia Wewengkang, Nur Iedha Tertiana, Farida Zharfani Muslim, Muhammad Yusuf, Shintya Octaviana Baliulina, Vanessa Pradna Adyana Daud, Aurielle Annalicia Setiawan, Fahrul Nurkolis
Summary: This study evaluated the anticancer activity of C. racemosa on HeLa cervical cancer cells. The results showed that C. racemosa extract increased the expression of pro-apoptotic proteins, induced cell apoptosis, and reduced the viability of HeLa cells. Therefore, C. racemosa extract has potential as a cervical cancer therapy.
FRONTIERS IN ONCOLOGY
(2022)
Article
Polymer Science
Bao Le, Duy Thanh Do, Hien Minh Nguyen, Bich Hang Do, Huong Thuy Le
Summary: This study found that low molecular sulfate polysaccharides from Caulerpa lentillifera exhibit anti-adhesive activity against Helicobacter pylori, promote macrophage proliferation, decrease nitric oxide production, and protect gastric adenocarcinoma cells from H. pylori invasion by inhibiting the IL-8/NF-kappa B axis.
Article
Biology
Pradtana Choosuwan, Jantana Praiboon, Korawinwich Boonpisuttinant, Anirut Klomjit, Narongrit Muangmai, Rapeeporn Ruangchuay, Anong Chirapart
Summary: This study evaluated the effects of ethanolic extracts from twelve seaweeds on tyrosinase inhibition and melanin synthesis. The results showed that the ethanolic extracts of Caulerpa racemosa, Ulva intestinalis, and Lobophora challengeriae had inhibitory effects on melanin production and intracellular tyrosinase levels. These seaweeds can be potential sources of natural tyrosinase inhibitors for therapeutic or cosmetic applications in the future.
Article
Immunology
Yasemin Ogul, Fatma Gur, Mustafa Cengiz, Bahri Gur, Refik Ali Sari, Ahmet Kiziltunc
Summary: This study evaluated the oxidant and anti-oxidant levels of RA patients and their impacts on disease activity through in silico studies. Results showed increased oxidative stress, weakened defense system, and increased ROS production in RA patients. Additionally, molecular docking studies confirmed the results on SOD and CAT activity.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Food Science & Technology
Manel Masmoudi, Hela Yaich, Maha Borchani, Rafika Mbarki, Hamadi Attia
Summary: The study showed that partially substituting wheat flour with jujube flour or jujube fiber concentrate had minimal impact on the quality of biscuits, while improving their nutritional value. The texture and sensory qualities of the biscuits remained good at appropriate substitution levels.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2021)
Article
Polymer Science
Lidiia Kolzunova, Elena Shchitovskaya, Maxim Karpenko
Summary: The study demonstrates the advantages of the electrochemical approach in the formation of polymer/metal nanoparticle composites, simplifying the production process and reducing formation time. It also shows the possibility of single-stage formation of such composites and confirms the energetic favorability of including gold nanoparticles into the polymethylolacrylamide film.
Article
Environmental Sciences
Krishnamoorthy Elavarasan, Anuj Kumar, Devananda Uchoi, C. S. Tejpal, George Ninan, A. A. Zynudheen
WASTE AND BIOMASS VALORIZATION
(2017)
Article
Food Science & Technology
Krishnamoorthy Elavarasan, Bangalore Aswathnarayan Shamasundar
FOOD SCIENCE AND BIOTECHNOLOGY
(2017)
Article
Fisheries
K. Elavarasan, Vinitha Verma, B. A. Shamasundar
INDIAN JOURNAL OF FISHERIES
(2017)
Article
Biochemistry & Molecular Biology
C. S. Tejpal, N. S. Chatterjee, K. Elavarasan, R. G. K. Lekshmi, R. Anandan, K. K. Asha, B. Ganesan, S. Mathew, C. N. Ravishankar
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2017)
Article
Food Science & Technology
D. Pavan Kumar, M. V. Chandra, K. Elavarasan, B. A. Shamasundar
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
(2018)
Article
Food Science & Technology
Anuj Kumar, Krishnamoorthy Elavarasan, Pankaj Kishore, Devananda Uchoi, Hanjabam Mandakini Devi, George Ninan, A. A. Zynudheen
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2017)
Article
Food Science & Technology
C. S. Tejpal, P. Vijayagopal, K. Elavarasan, D. Linga Prabu, R. G. K. Lekshmi, K. K. Asha, R. Anandan, N. S. Chatterjee, S. Mathew
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2017)
Article
Food Science & Technology
Krishnamoorthy Elavarasan, Bangalore Aswathnarayan Shamasundar
JOURNAL OF FOOD QUALITY
(2018)
Article
Food Science & Technology
Anuj Kumar, Krishnamoorthy Elavarasan, Mandakini Devi Hanjabam, P. K. Binsi, C. O. Mohan, A. A. Zynudheen, Ashok K. Kumar
LWT-FOOD SCIENCE AND TECHNOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Pavan Kumar Dara, Krishnamoorthy Elavarasan, Bangalore Aswathnarayan Shamasundar
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
(2020)
Article
Food Science & Technology
Krishnamoorthy Elavarasan, Bangalore Aswathnarayan Shamasundar
Summary: Fish protein hydrolysates from fresh water carps were prepared using papain enzyme with varying degrees of hydrolysis, showing species-specific and degree-specific antioxidant properties. Particularly, FPH from C. catla exhibited effective antioxidant activity at different concentrations and was fractionated using size exclusion chromatography to reveal different peptide fractions.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2022)
Review
Chemistry, Medicinal
Girija Gajanan Phadke, Nikheel Bhojraj Rathod, Fatih Ozogul, Krishnamoorthy Elavarasan, Muthusamy Karthikeyan, Kyung-Hoon Shin, Se-Kwon Kim
Summary: Developing peptide-based drugs from natural sources, such as aquatic organisms, shows promise in addressing lifestyle mediated diseases. Studies have shown that peptides enriched with bioactive properties can modulate human physiological functions beneficially, potentially offering new therapeutic options. However, further research and regulatory clearance are needed to explore the use of fish waste as a source of bioactive peptides for supplementation or therapeutics.
Article
Biotechnology & Applied Microbiology
S. Chinnadurai, K. Elavarasan, V. Geethalakshmi, V. Kripa, K. S. Mohamed
Summary: The effect of depuration on naturally contaminated tropical bivalve molluscs was investigated in this study. The elimination of fecal indicators and bacterial pathogens was influenced by temperature, salinity, and body-size of the animals. The research suggests that using a static depuration system at room temperature, a salinity range of 25-35 ps mu, and medium-sized bivalves is the optimum condition for producing microbiologically safe bivalves for live consumption within 36 hours.
Article
Agronomy
M. H. Thimmappa, A. Manjunatha Reddy, R. M. Prabhu, K. Elavarasan
AGRICULTURAL RESEARCH
(2019)