Apolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis

The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4

(2014) Christine Goy et al.   EXPERIMENTAL GERONTOLOGY

Protective effects of the thioredoxin and glutaredoxin systems in dopamine-induced cell death

(2014) Lisa Arodin et al.   FREE RADICAL BIOLOGY AND MEDICINE

SCO2 Induces p53-Mediated Apoptosis by Thr845 Phosphorylation of ASK-1 and Dissociation of the ASK-1-Trx Complex

(2013) E. Madan et al.   MOLECULAR AND CELLULAR BIOLOGY

DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway

(2012) Joo-Young Im et al.   HUMAN MOLECULAR GENETICS

LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease

(2012) Carlos Spuch et al.   Frontiers in Physiology

Side Chain-oxidized Oxysterols Regulate the Brain Renin-Angiotensin System through a Liver X Receptor-dependent Mechanism

(2011) Laura Mateos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen protects against amyloid-β toxicity by estrogen receptor α-mediated inhibition of Daxx translocation

(2011) Laura Mateos et al.   NEUROSCIENCE LETTERS

Protein levels of heat shock proteins 27, 32, 60, 70, 90 and thioredoxin-1 in amnestic mild cognitive impairment: An investigation on the role of cellular stress response in the progression of Alzheimer disease

(2010) Fabio Di Domenico et al.   BRAIN RESEARCH

Apolipoprotein E expression promotes lung adenocarcinoma proliferation and migration and as a potential survival marker in lung cancer

(2010) Wen-Pin Su et al.   LUNG CANCER

DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex

(2010) Joo-Young Im et al.   NEUROSCIENCE RESEARCH

ApoE4 reduces glutamate receptor function and synaptic plasticity by selectively impairing ApoE receptor recycling

(2010) Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DJ-1 Loss by Glutaredoxin but Not Glutathione Depletion Triggers Daxx Translocation and Cell Death

(2009) Uzma Saeed et al.   ANTIOXIDANTS & REDOX SIGNALING

Glycosylation- and phosphorylation-dependent intracellular transport of lysosomal hydrolases

(2009) Sandra Pohl et al.   BIOLOGICAL CHEMISTRY

Mutant p53 Disrupts the Stress MAPK Activation Circuit Induced by ASK1-Dependent Stabilization of Daxx

(2009) T. Kitamura et al.   CANCER RESEARCH

Association between enzymatic and non-enzymatic antioxidant defense mechanism with apolipoprotein E genotypes in Alzheimer disease

(2008) Hadi Kharrazi et al.   CLINICAL BIOCHEMISTRY

Parkin-mediated ubiquitination regulates phospholipase C-γ1

(2008) Nodi Dehvari et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain

(2008) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE