Side Chain-oxidized Oxysterols Regulate the Brain Renin-Angiotensin System through a Liver X Receptor-dependent Mechanism

Potential Mechanisms Linking Cholesterol to Alzheimer's Disease-like Pathology in Rabbit Brain, Hippocampal Organotypic Slices, and Skeletal Muscle

(2017) Othman Ghribi   JOURNAL OF ALZHEIMERS DISEASE

Absence of ApoE Upregulates Murine Brain ApoD and ABCA1 Levels, But Does Not Affect Brain Sterol Levels, While Human ApoE3 and Human ApoE4 Upregulate Brain Cholesterol Precursor Levels

(2017) Paula J. Jansen et al.   JOURNAL OF ALZHEIMERS DISEASE

A second class of nuclear receptors for oxysterols: Regulation of RORα and RORγ activity by 24S-hydroxycholesterol (cerebrosterol)

(2010) Yongjun Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

On the mechanism of accumulation of cholestanol in the brain of mice with a disruption of sterol 27-hydroxylase

(2010) Ann Båvner et al.   JOURNAL OF LIPID RESEARCH

Genetic connections between neurological disorders and cholesterol metabolism

(2010) Ingemar Björkhem et al.   JOURNAL OF LIPID RESEARCH

Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway

(2009) Shun-Guang Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Devil and angel in the renin–angiotensin system: ACE–angiotensin II–AT1 receptor axis vs. ACE2–angiotensin-(1–7)–Mas receptor axis

(2009) Masaru Iwai et al.   HYPERTENSION RESEARCH

Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis

(2009) Rebecca Schüle et al.   JOURNAL OF LIPID RESEARCH

25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR

(2009) Amalia Trousson et al.   JOURNAL OF NEUROCHEMISTRY

Combination renin-angiotensin system blockade with the renin inhibitor aliskiren in hypertension

(2009) Timothy WR Doulton et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Oxysterols and neurodegenerative diseases

(2009) Ingemar Björkhem et al.   MOLECULAR ASPECTS OF MEDICINE

Effects of Hypertension and Hypercholesterolemia on Cognitive Functioning in Patients With Alzheimer Disease

(2008) Felicia C. Goldstein et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Activity-Regulated Cytoskeleton-Associated Protein in Rodent Brain is Down-Regulated by High Fat Dietin vivoand by 27-Hydroxycholesterolin vitro

(2008) Laura Mateos et al.   BRAIN PATHOLOGY

Continuous Activation of Renin-Angiotensin System Impairs Cognitive Function in Renin/Angiotensinogen Transgenic Mice

(2008) Shinji Inaba et al.   HYPERTENSION

Brain renin angiotensin in disease

(2008) M. Ian Phillips et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Analysis of CYP7B1 in non-consanguineous cases of hereditary spastic paraplegia

(2008) Rebecca Schüle et al.   NEUROGENETICS

An Intracellular Renin-Angiotensin System in Neurons: Fact, Hypothesis, or Fantasy

(2008) Justin L. Grobe et al.   PHYSIOLOGY

Exaggeration of Focal Cerebral Ischemia in Transgenic Mice Carrying Human Renin and Human Angiotensinogen Genes

(2008) Shinji Inaba et al.   STROKE

GW3965, a synthetic liver X receptor (LXR) agonist, reduces angiotensin II-mediated pressor responses in Sprague-Dawley rats

(2007) C E Leik et al.   BRITISH JOURNAL OF PHARMACOLOGY