Toxicology Evaluation of Drugs Administered via Uncommon Routes: Intranasal, Intraocular, Intrathecal/Intraspinal, and Intra-Articular

Evaluation of Intracameral Pentablock Copolymer Thermosensitive Gel for Sustained Drug Delivery to the Anterior Chamber of the Eye

(2017) Elizabeth Schaefer et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

The Polyanalgesic Consensus Conference (PACC): Recommendations for Intrathecal Drug Delivery: Guidance for Improving Safety and Mitigating Risks

(2017) Timothy R. Deer et al.   NEUROMODULATION

Inflammation and immunogenicity limit the utility of the rabbit as a nonclinical species for ocular biologic therapeutics

(2017) Christina L.Zuch de Zafra et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

In vivo Pharmacological Evaluations of Pilocarpine-Loaded Antioxidant-Functionalized Biodegradable Thermogels in Glaucomatous Rabbits

(2017) Shih-Feng Chou et al.   Scientific Reports

Intrathecal Catheterization and Drug Delivery in Guinea Pigs

(2016) Kelly A. Eddinger et al.   ANESTHESIOLOGY

Symposium Summary

(2016) Jeffrey S. Tepper et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Posterior Segment Drug Delivery Devices: Current and Novel Therapies in Development

(2016) Pooja Bansal et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

How Much Nonclinical Safety Data Are Required for a Clinical Study in Ophthalmology?

(2016) Gary D. Novack et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Fourier domain optical coherence tomography to assess the iridocorneal angle and correlation study in a large Caucasian population

(2016) José Ignacio Fernández-Vigo et al.   BMC Ophthalmology

Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs

(2016) Atsushi Miyanohara et al.   Molecular Therapy-Methods & Clinical Development

Intranasal Drug Delivery: How, Why and What for?

(2016) Anaísa Pires et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Anterolateral ligament anatomy: a comparative anatomical study

(2015) Sheila Jean McNeill Ingham et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Scientific and Regulatory Policy Committee

(2015) Roy Kerlin et al.   TOXICOLOGIC PATHOLOGY

Impaired sense of smell and altered olfactory system in RAG-1−∕− immunodeficient mice

(2015) Lorenza Rattazzi et al.   Frontiers in Neuroscience

Outer brain barriers in rat and human development

(2015) Christian B. Brøchner et al.   Frontiers in Neuroscience

Spinal Fluid Biomechanics and Imaging: An Update for Neuroradiologists

(2014) V. Haughton et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Intranasal delivery of systemic-acting drugs: Small-molecules and biomacromolecules

(2014) Ana Fortuna et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Ocular delivery of macromolecules

(2014) Yoo Chun Kim et al.   JOURNAL OF CONTROLLED RELEASE

Immunology

(2014) Elina Toskala   International Forum of Allergy & Rhinology

Physiology-Based MR Imaging Assessment of CSF Flow at the Foramen Magnum with a Valsalva Maneuver

(2013) R.A. Bhadelia et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Role of Meningeal Mast Cells in Intrathecal Morphine–evoked Granuloma Formation

(2013) Tony L. Yaksh et al.   ANESTHESIOLOGY

Intrathecal Substance P-Saporin in the Dog

(2013) Ashley J. Wiese et al.   ANESTHESIOLOGY

Insights into direct nose to brain delivery: current status and future perspective

(2013) Deepti Mittal et al.   DRUG DELIVERY

Anterior cruciate ligament: an anatomical exploration in humans and in a selection of animal species

(2013) Gof Tantisricharoenkul et al.   KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY

Recording Odor-Evoked Response Potentials at the Human Olfactory Epithelium

(2012) H. Lapid et al.   CHEMICAL SENSES

What constitutes an “animal model of osteoarthritis” – the need for consensus?

(2012) C.B. Little et al.   OSTEOARTHRITIS AND CARTILAGE

Intranasal drug delivery: An efficient and non-invasive route for systemic administration

(2012) Stanislas Grassin-Delyle et al.   PHARMACOLOGY & THERAPEUTICS

Visualization of Murine Intranasal Dosing Efficiency Using Luminescent Francisella tularensis: Effect of Instillation Volume and Form of Anesthesia

(2012) Mark A. Miller et al.   PLoS One

Iridocorneal angle measurements in mammalian species: normative data by optical coherence tomography

(2012) Alexandra Almazan et al.   VETERINARY OPHTHALMOLOGY

Anatomical and Histological Factors Affecting Intranasal Drug and Vaccine Delivery

(2012) Sveinbjorn Gizurarson   Current Drug Delivery

Nasal drug delivery devices: characteristics and performance in a clinical perspective—a review

(2012) Per Gisle Djupesland   Drug Delivery and Translational Research

A comparative anatomical study of the human knee and six animal species

(2011) Benedikt L. Proffen et al.   KNEE

Histopathological Evaluation of the Nervous System in National Toxicology Program Rodent Studies

(2011) Deepa B. Rao et al.   TOXICOLOGIC PATHOLOGY

Anatomy and physiology of cerebrospinal fluid

(2011) L. Sakka et al.   European Annals of Otorhinolaryngology-Head and Neck Diseases

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rabbit

(2010) S. Laverty et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the guinea pig

(2010) V.B. Kraus et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rat

(2010) N. Gerwin et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Incidences and Range of Spontaneous Findings in Control Cynomolgus Monkeys (Macaca fascicularis) Used in Toxicity Studies

(2010) Ronnie Chamanza et al.   TOXICOLOGIC PATHOLOGY

Cerebrospinal Fluid and Spinal Cord Distribution of Hyperbaric Bupivacaine and Baclofen during Slow Intrathecal Infusion in Pigs

(2009) Sean H. Flack et al.   ANESTHESIOLOGY

Joint aspiration and injection and synovial fluid analysis

(2009) Philip Courtney et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Protective effects of a cathepsin K inhibitor, SB-553484, in the canine partial medial meniscectomy model of osteoarthritis

(2009) J.R. Connor et al.   OSTEOARTHRITIS AND CARTILAGE

Animal Models for Cartilage Regeneration and Repair

(2009) Constance R. Chu et al.   TISSUE ENGINEERING PART B-REVIEWS

Safety Evaluation of Ocular Drug Delivery Formulations: Techniques and Practical Considerations

(2008) Brian G. Short   TOXICOLOGIC PATHOLOGY