Article
Oncology
Mustafa Hepokur, Esma Ecem Ersoy, Berkay Kisakurek, Fatma Sali, Ebubekir Durmus, Veysel Aykut, Halit Oguz, Fehim Esen
Summary: The purpose of this study was to track and define the changes following intravitreal injection of different anti-vascular endothelial growth factor (VEGF) medications or dexamethasone implant. The results showed that dexamethasone implant widened the iridocorneal angle, while anti-VEGF medications did not have a similar effect.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2023)
Article
Multidisciplinary Sciences
Min-Su Kim, Ki-Yup Nam, Young Hoon Hwang, Min-Woo Lee, Woo-Hyuk Lee, Hyung-Bin Lim, Jung-Yeul Kim
Summary: It was found that Weiss ring located near the optic disc can affect the measurement of peripapillary retinal nerve fiber layer (pRNFL) thickness, especially in the inferior quadrant and average values. Therefore, it is important to consider the presence of Weiss ring when analyzing pRNFL thickness.
SCIENTIFIC REPORTS
(2022)
Article
Ophthalmology
Kwang-Eon Choi, Vu Thi Que Anh, Jong-Hyun Oh, Cheolmin Yun, Seong-Woo Kim
Summary: This study aimed to present normative data of OCT, electrophysiological, and ocular biometry parameters in minipigs, and found differences in retinal sublayer thickness at various locations. The implicit time of ERGs was longer in scotopic conditions than in photopic conditions, while VEPs showed shorter implicit times in minipigs.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Eisuke Shimizu, Hiroyuki Yazu, Naohiko Aketa, Ryota Yokoiwa, Shinri Sato, Junichiro Yajima, Taiichiro Katayama, Rio Sato, Makoto Tanji, Yasunori Sato, Yoko Ogawa, Kazuo Tsubota
Summary: This study demonstrates a high correlation between measurements obtained with a portable smart eye camera (SEC) and conventional devices for assessing anterior chamber depth (ACD) and iridocorneal angle. The SEC showed good subjective and objective assessment functions, indicating its adequate performance for ACD evaluation and angle estimation.
Article
Biochemical Research Methods
Vikram Barauah, Shyon Parsa, Naail Chowdhury, Thomas Milner, Henry Grady Rylander III
Summary: This study investigates the detection of morphological changes in Bacillus subtilis using scattering angle resolved optical coherence tomography (SAR-OCT). The results show significant differences in the distribution of backscattering angle during the rod-to-coccus shape transition of the bacteria. The study supports the potential of utilizing SAR-OCT to detect bacterial morphological changes.
JOURNAL OF BIOMEDICAL OPTICS
(2022)
Article
Medicine, General & Internal
Gustavo Espinoza, Katheriene Iglesias, Juan C. Parra, Ignacio Rodriguez-Una, Sergio Serrano-Gomez, Angelica M. Prada, Virgilio Galvis
Summary: This study evaluated the agreement and reproducibility of ACA measurements obtained using the built-in software of the CASIA2 and the measurements derived from expert clinicians. The results showed that the CASIA2 software had excellent repeatability and consistency, reliably measuring ACA parameters in healthy individuals.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Carolina Arruabarrena, Antonio Rodriguez-Miguel, Fernando de Aragon-Gomez, Purificacion Escamez, Ingrid Rosado, Miguel A. Teus
Summary: The purpose of this study was to establish normative data for macular thickness and volume in a diabetic population. The researchers used spectral-domain optical coherence tomography (SD-OCT) to observe and compare macular thickness and volume between diabetic patients and a reference population. The results showed that diabetic patients had thinner macular thickness and volume compared to the reference population.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Ruru Chen, Hengli Lian, Colm McAlinden, Eirini Skiadaresi, Siyu Liu, Ting Wan, Kai Diao, Hongxian Pan, Jia Qu, Jinhai Huang, Yiyu Li
Summary: The study established a normative database for vascular density in macular, disc, and peripapillary regions in healthy myopic children and found that VD in different regions had various influencing factors, mainly closely correlated with axial length and signal strength index.
FRONTIERS IN MEDICINE
(2022)
Article
Optics
Howard Peng Sin Heng, Chi Shu, Wei Zheng, Zhiwei Huang
Summary: We report the development of a novel coaxial double-clad-fiber (DCF) and graded-index (GRIN) fiberoptic Raman probe for enhancing in vivo epithelial tissue Raman measurements. The probe can acquire high-quality Raman spectra from various oral tissues within sub-seconds and detect subtle biochemical differences between different epithelial tissues, suggesting its potential for in vivo diagnosis and characterization.
Article
Cell Biology
Hugo Ferreira, Joao Martins, Paula I. Moreira, Antonio Francisco Ambrosio, Miguel Castelo-Branco, Pedro Serranho, Rui Bernardes
Summary: This study established a normative database of retinal thickness in mice aged one to four months, providing data for studying the aging of control and disease model mice. Results showed differences in thickness at different layers, a nasal-temporal asymmetry, and significant differences in thickness between the transgenic mouse group and the normative database.
Article
Ophthalmology
Kwang-Eon Choi, Vu Thi Que Anh, Cheolmin Yun, Young-Jin Kim, Hachul Jung, Heejong Eom, Dongkwan Shin, Seong-Woo Kim
Summary: The study presented normative data of multimodal examinations including ocular biometry, electrophysiological tests, and OCT parameters for cynomolgus monkeys, serving as reference values for further preclinical studies.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2021)
Article
Biochemical Research Methods
Le Han, Bingyao Tan, Leopold Schmetterer, Kostadinka Bizheva
Summary: A novel decor relation-based approach is proposed for measuring localized transverse flow velocity using line-scan optical coherence tomography (OCT). The new method allows for separation of the flow velocity component along the line-illumination direction from other components, diffusion motion, and noise-induced distortion. Verification was done by imaging flow in a glass capillary and a microfluidic device, mapping the flow velocity distribution within the illuminated area. This method has potential for mapping three-dimensional flow velocity fields in both ex-vivo and in-vivo applications.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Multidisciplinary Sciences
Henry Shen-Lih Chen, Xiao Chun Ling, Da-Wen Lu, Lan-Hsing Chuang, Wei-Wen Su, Yung-Sung Lee, Wei-Chi Wu, Po-Han Yeh
Summary: This study compares the diagnostic ability of regular and long axial length databases in identifying glaucoma among highly myopic individuals. The use of long axial length database significantly improves the specificity and diagnostic accuracy in distinguishing glaucomatous eyes from nonglaucomatous eyes in this population.
SCIENTIFIC REPORTS
(2022)
Article
Instruments & Instrumentation
Yushu Ma, Yuqian Zhao, Huiwen Jiang, Yang Lin, Ang Li, Ziyue Meng, Jian Liu, Yao Yu, Yi Wang, Zhonghai He, Wenbo Shi, Zhenhe Ma
Summary: Abnormal blood flow in the early stage of embryonic heart can lead to cardiac defects. Accurate flow measurement in the embryonic heart is important for related studies. Optical coherence tomography (OCT) is a noninvasive imaging approach that can provide high-resolution flow velocity distribution information. The proposed method in this study introduces a dividing head to probe the arm of OCT, allowing for the measurement of the Doppler angle and the calculation of absolute flow velocity. The method is validated using a capillary phantom and further applied to measure blood flow in the early stage of chicken embryo in vivo.
INFRARED PHYSICS & TECHNOLOGY
(2022)
Article
Ophthalmology
Efthymia Prousali, Anna Dastiridou, Anna-Bettina Haidich, Argyrios Tzamalis, Nikolaos Ziakas, Asimina Mataftsi
Summary: In this study, school-aged children with a history of sr-ROP had narrower angles compared to preterm- and term-born children. AS-OCT demonstrated structural differences of the iridocorneal angle in sr-ROP, possibly reflecting a mild developmental arrest of the anterior segment.
INTERNATIONAL OPHTHALMOLOGY
(2021)
