Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

Chronic Kidney Disease in Kidney Stone Formers

(2011) A. D. Rule et al.   Clinical Journal of the American Society of Nephrology

Cutting Edge: Cyclic Polypeptide and Aminoglycoside Antibiotics Trigger IL-1  Secretion by Activating the NLRP3 Inflammasome

(2011) R. Allam et al.   JOURNAL OF IMMUNOLOGY

Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1  Secretion through the NLRP3 Inflammasome In Vitro

(2011) B. Pazar et al.   JOURNAL OF IMMUNOLOGY

The Inflammasomes in Kidney Disease

(2011) H.-J. Anders et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Renal Mononuclear Phagocytic System

(2011) P. J. Nelson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis

(2011) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

Hyperoxaluria: a gut–kidney axis?

(2011) Stef Robijn et al.   KIDNEY INTERNATIONAL

Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy

(2011) Andrea Ribeiro et al.   KIDNEY INTERNATIONAL

Polyene Macrolide Antifungal Drugs Trigger Interleukin-1β Secretion by Activating the NLRP3 Inflammasome

(2011) Murthy Narayana Darisipudi et al.   PLoS One

Anti-GBM Glomerulonephritis Involves IL-1 but Is Independent of NLRP3/ASC Inflammasome-Mediated Activation of Caspase-1

(2011) Julia Lichtnekert et al.   PLoS One

Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: Results of a multicenter, phase II, dose-ranging study

(2010) Alexander So et al.   ARTHRITIS AND RHEUMATISM

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Renal macrophage migration and crystal phagocytosis via inflammatory-related gene expression during kidney stone formation and elimination in mice: Detection by association analysis of stone-related gene expression and microstructural observation

(2010) Atsushi Okada et al.   JOURNAL OF BONE AND MINERAL RESEARCH

An Inflammasome-Independent Role for Epithelial-Expressed Nlrp3 in Renal Ischemia-Reperfusion Injury

(2010) A. A. Shigeoka et al.   JOURNAL OF IMMUNOLOGY

Ischemia Reperfusion Induces IFN Regulatory Factor 4 in Renal Dendritic Cells, which Suppresses Postischemic Inflammation and Prevents Acute Renal Failure

(2010) S. Lassen et al.   JOURNAL OF IMMUNOLOGY

Toll-Like Receptors and Danger Signaling in Kidney Injury

(2010) H.-J. Anders   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

(2010) A. Vilaysane et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal histopathology and crystal deposits in patients with small bowel resection and calcium oxalate stone disease

(2010) Andrew P. Evan et al.   KIDNEY INTERNATIONAL

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning?

(2009) Kenneth McMartin   CLINICAL TOXICOLOGY

Resident Dendritic Cells Prevent Postischemic Acute Renal Failure by Help of Single Ig IL-1 Receptor-Related Protein

(2009) M. Lech et al.   JOURNAL OF IMMUNOLOGY

The primary hyperoxalurias

(2009) Bernd Hoppe et al.   KIDNEY INTERNATIONAL

Interleukin-1β and the Autoinflammatory Diseases

(2009) Charles A. Dinarello   NEW ENGLAND JOURNAL OF MEDICINE

Physiopathology and etiology of stone formation in the kidney and the urinary tract

(2009) Andrew P. Evan   PEDIATRIC NEPHROLOGY

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Successful treatment of resistant pseudogout with anakinra

(2008) Dennis McGonagle et al.   ARTHRITIS AND RHEUMATISM

Genome-Wide Analysis of Genes Related to Kidney Stone Formation and Elimination in the Calcium Oxalate Nephrolithiasis Model Mouse: Detection of Stone-Preventive Factors and Involvement of Macrophage Activity

(2008) Atsushi Okada et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Synaptic Ultrastructural Alterations Anticipate the Development of Neuroaxonal Dystrophy in Sympathetic Ganglia of Aged and Diabetic Mice

(2008) Robert E. Schmidt et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE