Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations

Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis

(2016) Ariel B. Ganz et al.   FASEB JOURNAL

Assessment of Total Choline Intakes in the United States

(2016) Taylor C. Wallace et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

The hepatic circadian clock regulates the choline kinase α gene through the BMAL1-REV-ERBα axis

(2015) Aline Gréchez-Cassiau et al.   CHRONOBIOLOGY INTERNATIONAL

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis

(2015) Ji Miao et al.   Nature Communications

The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance

(2015) Manya Warrier et al.   Cell Reports

Alterations of Choline Phospholipid Metabolism in Endometrial Cancer Are Caused by Choline Kinase Alpha Overexpression and a Hyperactivated Deacylation Pathway

(2014) S. Trousil et al.   CANCER RESEARCH

Identification of new genetic polymorphisms that alter the dietary requirement for choline and vary in their distribution across ethnic and racial groups

(2014) Kerry-Ann da Costa et al.   FASEB JOURNAL

Admixture Mapping and Subsequent Fine-Mapping Suggests a Biologically Relevant and Novel Association on Chromosome 11 for Type 2 Diabetes in African Americans

(2014) Janina M. Jeff et al.   PLoS One

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

The choline transporter-like family SLC44: Properties and roles in human diseases

(2013) Elisabeth Traiffort et al.   MOLECULAR ASPECTS OF MEDICINE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Correction: Phospholipid Biosynthesis Genes and Susceptibility to Obesity: Analysis of Expression and Polymorphisms

(2013) Neeraj K. Sharma et al.   PLoS One

Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans

(2012) Jian Yan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Choline Dehydrogenase Polymorphism rs12676 Is a Functional Variation and Is Associated with Changes in Human Sperm Cell Function

(2012) Amy R. Johnson et al.   PLoS One

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline

(2010) Jian Yan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Kennedy pathway-De novo synthesis of phosphatidylethanolamine and phosphatidylcholine

(2010) Federica Gibellini et al.   IUBMB LIFE

Aberrant Estrogen Regulation ofPEMTResults in Choline Deficiency-associated Liver Dysfunction

(2010) Mary E. Resseguie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impairedde NovoCholine Synthesis Explains Why PhosphatidylethanolamineN-Methyltransferase-deficient Mice Are Protected from Diet-induced Obesity

(2010) René L. Jacobs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo

(2010) Christopher J. Pynn et al.   JOURNAL OF LIPID RESEARCH

The impact of choline availability on muscle lipid metabolism

(2010) Vera Michel et al.   Food & Function

118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects

(2009) Gary M Shaw et al.   BMC Medical Genetics

Associations of folate and choline metabolism gene polymorphisms with orofacial clefts

(2009) A. Mostowska et al.   JOURNAL OF MEDICAL GENETICS

B-Vitamin Intake, One-Carbon Metabolism, and Survival in a Population-Based Study of Women with Breast Cancer

(2008) X. Xu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Choline metabolism and risk of breast cancer in a population-based study

(2008) Xinran Xu et al.   FASEB JOURNAL

Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: Implications in cancer therapy

(2008) Ana Ramírez de Molina et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Thematic Review Series: Glycerolipids.Phosphatidylcholine and choline homeostasis

(2008) Zhaoyu Li et al.   JOURNAL OF LIPID RESEARCH

Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: Common gene sequence variation and functional characterization

(2008) Fang Li et al.   MOLECULAR GENETICS AND METABOLISM

Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions

(2008) Karin Schläwicke Engström et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS