Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells

KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases

(2016) Roman P. Simon et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bladder cancer

(2016) Ashish M Kamat et al.   LANCET

Inhibition of Class I Histone Deacetylases 1 and 2 Promotes Urothelial Carcinoma Cell Death by Various Mechanisms

(2016) M. Pinkerneil et al.   MOLECULAR CANCER THERAPEUTICS

PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6

(2016) Junhu Wan et al.   NUCLEIC ACIDS RESEARCH

Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression

(2016) Sidra Majaz et al.   Cell and Bioscience

The Histone Acetyltransferase GCN5 Expression Is Elevated and Regulated by c-Myc and E2F1 Transcription Factors in Human Colon Cancer

(2015) Yan-Wei Yin et al.   GENE EXPRESSION

GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways

(2015) Kun Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma

(2015) X Gai et al.   Cell Death & Disease

Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression

(2015) H. Ogiwara et al.   Cancer Discovery

Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo

(2015) J M Gajer et al.   Oncogenesis

MYC interacts with the human STAGA coactivator complex via multivalent contacts with the GCN5 and TRRAP subunits

(2014) Na Zhang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

(2014) Joni Van der Meulen et al.   BLOOD

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

ARID1B is a specific vulnerability in ARID1A-mutant cancers

(2014) Katherine C Helming et al.   NATURE MEDICINE

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

PCAF-mediated Akt1 acetylation enhances the proliferation of human glioblastoma cells

(2014) Shuguang Zhang et al.   TUMOR BIOLOGY

Histone Acetyltransferase PCAF Is Required for Hedgehog-Gli-Dependent Transcription and Cancer Cell Proliferation

(2013) M. Malatesta et al.   CANCER RESEARCH

Lysine Acetyltransferase GCN5 Potentiates the Growth of Non-small Cell Lung Cancer via Promotion of E2F1, Cyclin D1, and Cyclin E1 Expression

(2013) Long Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling

(2013) Xin Zheng et al.   Molecular Cancer

The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3

(2012) Ian M. Love et al.   CELL CYCLE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

HAT4, a Golgi Apparatus-Anchored B-Type Histone Acetyltransferase, Acetylates Free Histone H4 and Facilitates Chromatin Assembly

(2011) Xiaohan Yang et al.   MOLECULAR CELL

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Human ATAC Is a GCN5/PCAF-containing Acetylase Complex with a Novel NC2-like Histone Fold Module That Interacts with the TATA-binding Protein

(2008) Yuan-Liang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY