PCAF-mediated acetylation of transcriptional factor HOXB9 suppresses lung adenocarcinoma progression by targeting oncogenic protein JMJD6

The oxygenase Jmjd6–a case study in conflicting assignments

(2015) Angelika Böttger et al.   BIOCHEMICAL JOURNAL

Kindlin-2 induced by TGF-β signaling promotes pancreatic ductal adenocarcinoma progression through downregulation of transcriptional factor HOXB9

(2015) Jun Zhan et al.   CANCER LETTERS

High expression of transcriptional factor HoxB9 predicts poor prognosis in patients with lung adenocarcinoma

(2015) Jun Zhan et al.   HISTOPATHOLOGY

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression

(2015) Junhu Wan et al.   NUCLEIC ACIDS RESEARCH

Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus

(2015) Toyoshi Yanagihara et al.   Nature Communications

Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients

(2014) J Zhan et al.   BRITISH JOURNAL OF CANCER

Ubiquitin-like Protein FAT10 Promotes the Invasion and Metastasis of Hepatocellular Carcinoma by Modifying  -Catenin Degradation

(2014) R. Yuan et al.   CANCER RESEARCH

An E2F1-HOXB9 Transcriptional Circuit Is Associated with Breast Cancer Progression

(2014) Aisulu Zhussupova et al.   PLoS One

JMJD6 Promotes Colon Carcinogenesis through Negative Regulation of p53 by Hydroxylation

(2014) Feng Wang et al.   PLOS BIOLOGY

Brd4 and JMJD6-Associated Anti-Pause Enhancers in Regulation of Transcriptional Pause Release

(2013) Wen Liu et al.   CELL

Decreased expression of HOXB9 is related to poor overall survival in patients with gastric carcinoma

(2013) Sumei Sha et al.   DIGESTIVE AND LIVER DISEASE

Lysyl 5-Hydroxylation, a Novel Histone Modification, by Jumonji Domain Containing 6 (JMJD6)

(2013) Motoko Unoki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New IASLC/ATS/ERS Classification and Invasive Tumor Size are Predictive of Disease Recurrence in Stage I Lung Adenocarcinoma

(2013) Naoki Yanagawa et al.   Journal of Thoracic Oncology

High expression of JMJD6 predicts unfavorable survival in lung adenocarcinoma

(2013) Ji Zhang et al.   TUMOR BIOLOGY

Homeodomain-containing protein HOXB9 regulates expression of growth and angiogenic factors, facilitates tumor growth in vitro and is overexpressed in breast cancer tissue

(2012) Bishakha Shrestha et al.   FEBS Journal

Silencing of homeobox B9 is associated with down-regulation of CD56 and extrathyroidal extension of tumor in papillary thyroid carcinoma

(2012) Jang-Hee Kim et al.   HUMAN PATHOLOGY

Pathology of Lung Cancer

(2011) William D. Travis   CLINICS IN CHEST MEDICINE

Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses

(2011) N. Chiba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1

(2011) J.-N. Boeckel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 post-translational modification: deregulated in tumorigenesis

(2010) Chao Dai et al.   TRENDS IN MOLECULAR MEDICINE

WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis

(2009) Don X. Nguyen et al.   CELL

HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis

(2009) T. Hayashida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing

(2009) Celia J. Webby et al.   SCIENCE

SnapShot: p53 Posttranslational Modifications

(2008) Jan-Philipp Kruse et al.   CELL

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL