Knockdown of XBP1 by RNAi in Mouse Granulosa Cells Promotes Apoptosis, Inhibits Cell Cycle, and Decreases Estradiol Synthesis

An immortalized steroidogenic goat granulosa cell line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis

(2017) Diqi YANG et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Knock-down of apoptosis inducing factor gene protects endoplasmic reticulum stress-mediated goat granulosa cell apoptosis

(2017) Diqi Yang et al.   THERIOGENOLOGY

The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained

(2016) Amit U. Joshi et al.   CELL CALCIUM

Herp depletion arrests the S phase of the cell cycle and increases estradiol synthesis in mouse granulosa cells

(2016) Fenglei CHEN et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Testosterone production by a Leydig tumor cell line is suppressed by hyperthermia-induced endoplasmic reticulum stress in mice

(2016) Jung-Hak Kim et al.   LIFE SCIENCES

The spatiotemporal hormonal orchestration of human folliculogenesis, early embryogenesis and blastocyst implantation

(2016) Craig S. Atwood et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endoplasmic reticulum stress in mouse decidua during early pregnancy

(2016) Xiao-Wei Gu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Dual role for the unfolded protein response in the ovary: adaption and apoptosis

(2016) Ning Huang et al.   Protein & Cell

Apoptosis in mammalian oocytes: a review

(2015) Meenakshi Tiwari et al.   APOPTOSIS

The roles of endoplasmic reticulum stress response in female mammalian reproduction

(2015) Yanzhou Yang et al.   CELL AND TISSUE RESEARCH

Enterovirus 71 mediates cell cycle arrest in S phase through non-structural protein 3D

(2015) Jinghua Yu et al.   CELL CYCLE

Involvement of the IRE1α-XBP1 Pathway and XBP1s-Dependent Transcriptional Reprogramming in Metabolic Diseases

(2015) Rong Wu et al.   DNA AND CELL BIOLOGY

Sex differences and rapid estrogen signaling: A look at songbird audition

(2015) Amanda A. Krentzel et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Evidence of the activation of unfolded protein response in granulosa and cumulus cells during follicular growth and maturation

(2015) Miyuki Harada et al.   GYNECOLOGICAL ENDOCRINOLOGY

Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human Osteosarcoma

(2015) Jielai Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Knockdown of CEBPβ by RNAi in porcine granulosa cells resulted in S phase cell cycle arrest and decreased progesterone and estradiol synthesis

(2014) Yan-Hong Zhen et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

(2014) Xi Chen et al.   NATURE

New directions in ER stress-induced cell death

(2013) Susan E. Logue et al.   APOPTOSIS

Unfolding protein response signaling is involved in development, maintenance, and regression of the corpus luteum during the bovine estrous cycle

(2013) Hyo-Jin Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vascular Endothelial Growth Factor and Angiogenesis

(2013) Jean-Sébastien Silvestre   CIRCULATION

Cdks, cyclins and CKIs: roles beyond cell cycle regulation

(2013) S. Lim et al.   DEVELOPMENT

The structural biology of oestrogen metabolism

(2013) Mark P. Thomas et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estrogen synthesis and signaling pathways during aging: from periphery to brain

(2013) Jie Cui et al.   TRENDS IN MOLECULAR MEDICINE

Porcine epidemic diarrhea virus N protein prolongs S-phase cell cycle, induces endoplasmic reticulum stress, and up-regulates interleukin-8 expression

(2013) Xingang Xu et al.   VETERINARY MICROBIOLOGY

Endoplasmic reticulum stress is involved in granulosa cell apoptosis during follicular atresia in goat ovaries

(2012) Pengfei Lin et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Inhibition of Endoplasmic Reticulum Stress Improves Mouse Embryo Development

(2012) Jin Yu Zhang et al.   PLoS One

Luman recruiting factor regulates endoplasmic reticulum stress in mouse ovarian granulosa cell apoptosis

(2012) Yanzhou Yang et al.   THERIOGENOLOGY

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders

(2011) Walter L. Miller et al.   ENDOCRINE REVIEWS

A cell for every season: the ovarian granulosa cell

(2011) David F. Albertini   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Anti-apoptotic function of Xbp1 as an IL-3 signaling molecule in hematopoietic cells

(2011) M Kurata et al.   Cell Death & Disease

Expression and localisation of Bcl-2 and Bax proteins in developing rat ovary

(2007) E. Gürsoy et al.   RESEARCH IN VETERINARY SCIENCE