Journal
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
Volume 69, Issue 5, Pages 566-573Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09637486.2017.1394449
Keywords
Phenolic acids; chlorogenic acid; gut microbiota; amino acids; serotonin
Categories
Funding
- National Natural Science Foundation of China [31360552]
- Excellent Young Scientist Award from Jiangxi Province [20153BCB23026]
- Natural Science Foundation of Jiangxi Province [20151BAB204036]
- State Key Laboratory of Food Science and Technology [SKLF-KF-201416, 201416, SKLF-ZZB-201515]
- Chinese Academy of Sciences [ZSZC-011]
Ask authors/readers for more resources
Chlorogenic acid (CGA) has many biological properties, including antibacterial, antioxidant and anti-inflammatory properties, and is one of the most abundant phenolic acids available in the human diet. The aim of this study was to investigate the effects of CGA on regulation of the gut microbiota, and on the levels of free amino acids and 5-hydroxytryptamine (5-HT, serotonin). Ninety-six healthy growing pigs were randomly assigned to two treatment groups: the Ctrl group (control group, standard feed) and the CGA group [standard feed plus 0.05% 3-caffeoylquinic acid (3-CQA)] for 60days. The diversity of the gut microbiota was increased after CGA supplementation. Changes in these microbes were significantly associated with the serum free amino acid levels and colonic 5-HT level. Compared with the Ctrl group, the levels of serum aspartic acid, threonine, alanine, arginine, and colonic 5-HT were significantly increased (p<.05). These data suggest important roles for CGA in regulating the gut microbiota and increasing the serum free amino acid levels.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available