Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage

Cigarette Smoke Induces Human Airway Epithelial Senescence via Growth Differentiation Factor 15 Production

(2016) Qun Wu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

New in vitro insights on a cell death pathway induced by magnolol and honokiol in aristolochic acid tubulotoxicity

(2016) Valérian Bunel et al.   FOOD AND CHEMICAL TOXICOLOGY

Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases

(2016) Kyung Eun Kim et al.   LIFE SCIENCES

Preclinical effects of honokiol on treating glioblastoma multiforme via G1 phase arrest and cell apoptosis

(2016) Chien-Ju Lin et al.   PHYTOMEDICINE

Cigarette smoke-mediated oxidative stress induces apoptosis via the MAPKs/STAT1 pathway in mouse lung fibroblasts

(2016) Hanbyeol Lee et al.   TOXICOLOGY LETTERS

The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages

(2016) Yunlong Yang et al.   Nature Communications

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance

(2016) N. Tasdemir et al.   Cancer Discovery

Cytotoxicity and apoptosis induction by e-cigarette fluids in human gingival fibroblasts

(2015) Silvia Sancilio et al.   Clinical Oral Investigations

Environment-induced lentigines: formation of solar lentigines beyond ultraviolet radiation

(2015) Motoki Nakamura et al.   EXPERIMENTAL DERMATOLOGY

Rosiglitazone ameliorates senescence-like phenotypes in a cellular photoaging model

(2015) Liang Chen et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Premature Skin Aging Features Rescued by Inhibition of NADPH Oxidase Activity in XPC-Deficient Mice

(2015) Mohsen Hosseini et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cigarette smoke alters cell cycle and induces inflammation in lung fibroblasts

(2015) C. D'Anna et al.   LIFE SCIENCES

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

(2015) Vinodkumar B. Pillai et al.   Nature Communications

Collaborative effects between the TNFα-TNFR1-macrophage axis and the VEGF-C-VEGFR3 signaling in lymphangiogenesis and metastasis

(2015) Renhai Cao et al.   OncoImmunology

Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes

(2014) Nobuhiro Kanaji et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cigarette Smoke-Induced Interleukin-1 Alpha May Be Involved in the Pathogenesis of Adult Acne

(2014) Yun Seok Yang et al.   Annals of Dermatology

Increased expression of the aryl hydrocarbon receptor in patients with chronic inflammatory skin diseases

(2014) Hye One Kim et al.   EXPERIMENTAL DERMATOLOGY

Does Phosphodiesterase Inhibition Lessen Facial Flap Necrosis in Tobacco Cigarette Users?

(2014) Miles Pfaff et al.   FACIAL PLASTIC SURGERY

Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions

(2014) Paola Di Meglio et al.   IMMUNITY

Anti-photoaging potential of Botulinum Toxin Type A in UVB-induced premature senescence of human dermal fibroblasts in vitro through decreasing senescence-related proteins

(2014) Felicia Permatasari et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Impact of long-term exposure to cigarette smoking on skin microvascular function

(2014) M. Rossi et al.   MICROVASCULAR RESEARCH

Red Light Interferes in UVA-Induced Photoaging of Human Skin Fibroblast Cells

(2014) Tianhui Niu et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

The Protective Effect of Baicalin against UVB Irradiation Induced Photoaging: An In Vitro and In Vivo Study

(2014) Jia-an Zhang et al.   PLoS One

TNFR1 mediates TNF-α-induced tumour lymphangiogenesis and metastasis by modulating VEGF-C-VEGFR3 signalling

(2014) Hong Ji et al.   Nature Communications

Honokiol suppresses TNF-α-induced migration and matrix metalloproteinase expression by blocking NF-κB activation via the ERK signaling pathway in rat aortic smooth muscle cells

(2013) Xiaoying Zhu et al.   ACTA HISTOCHEMICA

A cigarette component acrolein induces accelerated senescence in human diploid fibroblast IMR-90 cells

(2013) Cheng Luo et al.   BIOGERONTOLOGY

Tobacco smoke-induced skin pigmentation is mediated by the aryl hydrocarbon receptor

(2013) Motoki Nakamura et al.   EXPERIMENTAL DERMATOLOGY

Effects of Cigarette Smoke Extracts on the Growth and Senescence of Skin Fibroblasts In Vitro

(2013) Gao-yun Yang et al.   International Journal of Biological Sciences

IL-11, IL-1α, IL-6, and TNF-α are induced by solar radiation in vitro and may be involved in facial subcutaneous fat loss in vivo

(2013) Wen-Hwa Li et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes

(2013) Ying Ju Chen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Aging does not Enhance Experimental Cigarette Smoke-Induced COPD in the Mouse

(2013) Steven Zhou et al.   PLoS One

P21-PARP-1 Pathway Is Involved in Cigarette Smoke-Induced Lung DNA Damage and Cellular Senescence

(2013) Hongwei Yao et al.   PLoS One

Exposure to Atmospheric Particulate Matter Enhances Th17 Polarization through the Aryl Hydrocarbon Receptor

(2013) Michael van Voorhis et al.   PLoS One

Association of cigarette smoking with skin colour in Japanese women

(2013) Yuya Tamai et al.   TOBACCO CONTROL

Carbocysteine regulates innate immune responses and senescence processes in cigarette smoke stimulated bronchial epithelial cells

(2013) Elisabetta Pace et al.   TOXICOLOGY LETTERS

Heavy Smoking Before Coronary Surgical Procedures Affects the Native Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Gene Expression in Saphenous Vein Conduits

(2012) Sun Yongxin et al.   ANNALS OF THORACIC SURGERY

Honokiol induces caspase-independent paraptosis via reactive oxygen species production that is accompanied by apoptosis in leukemia cells

(2012) Yao Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia

(2012) Chie Ishikawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway

(2012) J.-W. Lin et al.   NEURO-ONCOLOGY

Apoptosis and necrosis: two different outcomes of cigarette smoke condensate-induced endothelial cell death

(2012) B Messner et al.   Cell Death & Disease

3-Deoxysappanchalcone Inhibits Tumor Necrosis Factor-α-Induced Matrix Metalloproteinase-9 Expression in Human Keratinocytes through Activated Protein-1 Inhibition and Nuclear Factor-Kappa B DNA Binding Activity

(2011) Ui Joung Youn et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Honokiol, a chemopreventive agent against skin cancer, induces cell cycle arrest and apoptosis in human epidermoid A431 cells

(2011) Chandeshwari Chilampalli et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Changes of oxygen content in facial skin before and after cigarette smoking

(2011) Guo-Biao Fan et al.   SKIN RESEARCH AND TECHNOLOGY

Honokiol, a phytochemical from the Magnolia plant, inhibits photocarcinogenesis by targeting UVB-induced inflammatory mediators and cell cycle regulators: development of topical formulation

(2010) M. Vaid et al.   CARCINOGENESIS

The Aryl Hydrocarbon Receptor Mediates UVB Radiation–Induced Skin Tanning

(2010) Bettina Jux et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Effects of Cigarette Smoke Condensate and Nicotine on Human Gingival Fibroblast-Mediated Collagen Degradation

(2010) Weiping Zhang et al.   JOURNAL OF PERIODONTOLOGY

Honokiol Inhibits the Progression of Collagen-Induced Arthritis by Reducing Levels of Pro-inflammatory Cytokines and Matrix Metalloproteinases and Blocking Oxidative Tissue Damage

(2010) Ki Rim Kim et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Exposure of human skin to benzo[a]pyrene: Role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation

(2010) C. Costa et al.   TOXICOLOGY

Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent

(2009) Levi E. Fried et al.   ANTIOXIDANTS & REDOX SIGNALING

Aryl Hydrocarbon Receptor Is an Ozone Sensor in Human Skin

(2009) Farrukh Afaq et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cigarette smoke condensate affects the collagen-degrading ability of human gingival fibroblasts

(2009) W. Zhang et al.   JOURNAL OF PERIODONTAL RESEARCH

Effects of a Brazilian herbal compound as a cosmetic eyecare for periorbital hyperchromia (“dark circles”)

(2009) Samara Eberlin et al.   Journal of Cosmetic Dermatology

Effect of greenCoffea arabicaL. seed oil on extracellular matrix components and water-channel expression inin vitroandex vivohuman skin models

(2009) Maria Del Carmen Velazquez Pereda et al.   Journal of Cosmetic Dermatology

Honokiol, a Constituent of Oriental Medicinal Herb Magnolia officinalis, Inhibits Growth of PC-3 Xenografts In vivo in Association with Apoptosis Induction

(2008) E.-R. Hahm et al.   CLINICAL CANCER RESEARCH

Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging

(2008) Stefania Briganti et al.   FREE RADICAL BIOLOGY AND MEDICINE