POMC maintains tumor-initiating properties of tumor tissue-derived long-term-cultured breast cancer stem cells

Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus

(2015) Sabrina Prudente et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Energy homeostasis genes and breast cancer risk: The influence of ancestry, body size, and menopausal status, the breast cancer health disparities study

(2015) Martha L. Slattery et al.   Cancer Epidemiology

Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat

(2015) Garron T. Dodd et al.   CELL

Estrogen regulates Hippo signaling via GPER in breast cancer

(2015) Xin Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

The cancer stem cell gamble

(2015) J. Kaiser   SCIENCE

Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor

(2015) Ying Liu et al.   Nature Communications

Melanin production through novel processing of proopiomelanocortin in the extracellular compartment of the auricular skin of C57BL/6 mice after UV-irradiation

(2015) Hiroyuki Yamamoto et al.   Scientific Reports

Gremlins Sabotage the Mechanisms of Cancer Stem Cell Differentiation

(2014) Joan Seoane   CANCER CELL

Retraction Note to: Bidirectional developmental potential in reprogrammed cells with acquired pluripotency

(2014) Haruko Obokata et al.   NATURE

Tackling the cancer stem cells — what challenges do they pose?

(2014) Diwakar R. Pattabiraman et al.   NATURE REVIEWS DRUG DISCOVERY

Positive expression of pro-opiomelanocortin (POMC) is a novel independent poor prognostic marker in surgically resected non-small cell lung cancer

(2014) Ligang Hao et al.   TUMOR BIOLOGY

Neuroendocrine and epithelial phenotypes in small-cell lung cancer: implications for metastasis and survival in patients

(2013) R Stovold et al.   BRITISH JOURNAL OF CANCER

Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance

(2013) Marc Schneeberger et al.   CELL

Central GLP-2 Enhances Hepatic Insulin Sensitivity via Activating PI3K Signaling in POMC Neurons

(2013) Xuemei Shi et al.   Cell Metabolism

A microRNA miR-34a-Regulated Bimodal Switch Targets Notch in Colon Cancer Stem Cells

(2013) Pengcheng Bu et al.   Cell Stem Cell

Nonsteroidal anti-inflammatory drugs suppress cancer stem cellsviainhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer

(2013) Chang Mo Moon et al.   INTERNATIONAL JOURNAL OF CANCER

Downregulation of Hepatoma-Derived Growth Factor Contributes to Retarded Lung Metastasis via Inhibition of Epithelial-Mesenchymal Transition by Systemic POMC Gene Delivery in Melanoma

(2013) H.-E. Tsai et al.   MOLECULAR CANCER THERAPEUTICS

Epidermal Growth Factor Receptor Variant III Contributes to Cancer Stem Cell Phenotypes in Invasive Breast Carcinoma

(2012) C. A. Del Vecchio et al.   CANCER RESEARCH

Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms

(2012) J. K. Singh et al.   CLINICAL CANCER RESEARCH

Role of Proopiomelanocortin-Derived Peptides and Their Receptors in the Osteoarticular System: From Basic to Translational Research

(2012) Markus Böhm et al.   ENDOCRINE REVIEWS

Breast cancer stem cell enrichment and isolation by mammosphere culture and its potential diagnostic applications

(2012) Katayoon Saadin et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Targeted Expression of BikDD Eliminates Breast Cancer with Virtually No Toxicity in Noninvasive Imaging Models

(2012) X. Xie et al.   MOLECULAR CANCER THERAPEUTICS

Targeted Expression of miR-34a Using the T-VISA System Suppresses Breast Cancer Cell Growth and Invasion

(2012) Laisheng Li et al.   MOLECULAR THERAPY

Involvement of hypothalamic cyclooxygenase-2, interleukin-1β and melanocortin in the development of docetaxel-induced anorexia in rats

(2012) Kouichi Yamamoto et al.   TOXICOLOGY

An Alu Element–Associated Hypermethylation Variant of the POMC Gene Is Associated with Childhood Obesity

(2012) Peter Kuehnen et al.   PLoS Genetics

BikDD Eliminates Breast Cancer Initiating Cells and Synergizes with Lapatinib for Breast Cancer Treatment

(2011) Jing-Yu Lang et al.   CANCER CELL

Identification and expansion of cancer stem cells in tumor tissues and peripheral blood derived from gastric adenocarcinoma patients

(2011) Tie Chen et al.   CELL RESEARCH

EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas

(2011) Hidenori Fukuoka et al.   JOURNAL OF CLINICAL INVESTIGATION

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

(2011) Linh Vong et al.   NEURON

Nicotine Decreases Food Intake Through Activation of POMC Neurons

(2011) Y. S. Mineur et al.   SCIENCE

In vivo effects of a GPR30 antagonist

(2009) Megan K Dennis et al.   Nature Chemical Biology

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

Mechanisms of Leptin Action and Leptin Resistance

(2007) Martin G. Myers et al.   Annual Review of Physiology