SIRT1 Protects Human Lens Epithelial Cells Against Oxidative Stress by Inhibiting p53-Dependent Apoptosis

Updating the Mitochondrial Free Radical Theory of Aging: An Integrated View, Key Aspects, and Confounding Concepts

(2013) Gustavo Barja   ANTIOXIDANTS & REDOX SIGNALING

The role of SIRT1 in ocular aging

(2013) Tatsuya Mimura et al.   EXPERIMENTAL EYE RESEARCH

Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells bothin vitroandin vivo

(2012) Junghyun Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Changes in SIRT1 Expression and Its Downstream Pathways in Age-Related Cataract in Humans

(2011) Tianyu Zheng et al.   CURRENT EYE RESEARCH

Coenzyme Q10 prevents human lens epithelial cells from light-induced apoptotic cell death by reducing oxidative stress and stabilizing BAX / Bcl-2 ratio

(2010) Marcus Kernt et al.   ACTA OPHTHALMOLOGICA

Lipids and the ocular lens

(2010) Douglas Borchman et al.   JOURNAL OF LIPID RESEARCH

Free Radicals, Antioxidants and Eye Diseases: Evidence from Epidemiological Studies on Cataract and Age-Related Macular Degeneration

(2010) A.E. Fletcher   OPHTHALMIC RESEARCH

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes

(2009) Shin-ichiro Imai   Frontiers in Bioscience-Landmark

Silent information regulator, Sirtuin 1, and age-related diseases

(2009) Li Zeng et al.   Geriatrics & Gerontology International

Forkhead class O transcription factor 3a activation and Sirtuin1 overexpression in the hypertrophied myocardium of the diabetic Goto-Kakizaki rat

(2009) Erik Vahtola et al.   JOURNAL OF HYPERTENSION

Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis

(2007) Neetu Kalra et al.   LIFE SCIENCES