Elevated Galectin-9 Suppresses Th1 Effector Function and Induces Apoptosis of Activated CD4+ T Cells in Osteoarthritis

Galectin-1 Couples Glycobiology to Inflammation in Osteoarthritis through the Activation of an NF-κB–Regulated Gene Network

(2016) Stefan Toegel et al.   JOURNAL OF IMMUNOLOGY

Diagnosis and Longitudinal Assessment of Osteoarthritis

(2016) Shadpour Demehri et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Unicompartmental and bicompartmental knee osteoarthritis show different patterns of mononuclear cell infiltration and cytokine release in the affected joints

(2015) B. Moradi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

T-cell immunoglobulin domain and mucin domain 3 polymorphism affects cytokine expression in different cells and is associated with increased susceptibility to knee osteoarthritis

(2015) Jianmin Chen et al.   GENE

TIM-3 Genetic Variations Affect Susceptibility to Osteoarthritis by Interfering with Interferon Gamma in CD4+ T Cells

(2015) Shufeng Li et al.   INFLAMMATION

Impact of Exogenous Galectin-9 on Human T Cells

(2015) Claire Lhuillier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in peripheral blood immune cell composition in osteoarthritis

(2015) F. Ponchel et al.   OSTEOARTHRITIS AND CARTILAGE

CD8+ T Cell-Induced Expression of Tissue Inhibitor of Metalloproteinses-1 Exacerbated Osteoarthritis

(2013) Jeng-Long Hsieh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tim-3, a negative regulator of anti-tumor immunity

(2012) Ana Carrizosa Anderson   CURRENT OPINION IN IMMUNOLOGY

The Tim3-Galectin 9 Pathway Induces Antibacterial Activity in Human Macrophages Infected with Mycobacterium tuberculosis

(2012) I. Sada-Ovalle et al.   JOURNAL OF IMMUNOLOGY

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

Cell Surface Galectin-9 Expressing Th Cells Regulate Th17 and Foxp3+ Treg Development by Galectin-9 Secretion

(2012) Souichi Oomizu et al.   PLoS One

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

Tim-3 regulates pro- and anti-inflammatory cytokine expression in human CD14+ monocytes

(2011) Ying Zhang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tim-3 Negatively Regulates IL-12 Expression by Monocytes in HCV Infection

(2011) Ying Zhang et al.   PLoS One

Synovial inflammation in patients undergoing arthroscopic meniscectomy: Molecular characterization and relationship to symptoms

(2010) Carla R. Scanzello et al.   ARTHRITIS AND RHEUMATISM

Increased Tim-3 expression on peripheral lymphocytes from patients with rheumatoid arthritis negatively correlates with disease activity

(2010) Ying Liu et al.   CLINICAL IMMUNOLOGY

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

(2010) Rachel H. McMahan et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic Cells

(2010) Rosemarie H. DeKruyff et al.   JOURNAL OF IMMUNOLOGY

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE