Aucubin Alleviates Bleomycin-Induced Pulmonary Fibrosis in a Mouse Model

Aucubin and its hydrolytic derivative attenuate activation of hepatic stellate cells via modulation of TGF-β stimulation

(2017) Pei-Yu Lv et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The Novel mTOR Complex 1/2 Inhibitor P529 Inhibits Human Lung Myofibroblast Differentiation

(2017) Keith T. Ferguson et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

miR-18a-5p Inhibits Sub-pleural Pulmonary Fibrosis by Targeting TGF-β Receptor II

(2017) Qian Zhang et al.   MOLECULAR THERAPY

Mechanisms of Lung Fibrosis Resolution

(2016) Stephan W. Glasser et al.   AMERICAN JOURNAL OF PATHOLOGY

Amplified canonical transforming growth factor-β signallingviaheat shock protein 90 in pulmonary fibrosis

(2016) Zaneta Sibinska et al.   EUROPEAN RESPIRATORY JOURNAL

The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury

(2016) Ashish R. Kurundkar et al.   FASEB JOURNAL

Soluble Epoxide Hydrolase Inhibitor Suppresses the Expression of Triggering Receptor Expressed on Myeloid Cells-1 by Inhibiting NF-kB Activation in Murine Macrophage

(2016) Liang Dong et al.   INFLAMMATION

Hydroxysafflor Yellow A Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice

(2016) Ming Jin et al.   PHYTOTHERAPY RESEARCH

Regulation of 26S Proteasome Activity in Pulmonary Fibrosis

(2015) Nora Semren et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice

(2015) Yong Zhou et al.   CELL AND TISSUE RESEARCH

Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-κB and TGF-β1/Smad-2/-3 pathways

(2015) Haiying Tang et al.   CELL STRESS & CHAPERONES

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis

(2015) Katrin Palumbo-Zerr et al.   NATURE MEDICINE

Effect of pirfenidone on proliferation, TGF-β-induced myofibroblast differentiation and fibrogenic activity of primary human lung fibroblasts

(2014) Enrico Conte et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The pathogenesis of bleomycin-induced lung injury in animals and its applicability to human idiopathic pulmonary fibrosis

(2014) James D. Williamson et al.   EXPERIMENTAL LUNG RESEARCH

Fibroblasts in fibrosis: novel roles and mediators

(2014) Ryan T. Kendall et al.   Frontiers in Pharmacology

Aucubin, a naturally occurring iridoid glycoside inhibits TNF-α-induced inflammatory responses through suppression of NF-κB activation in 3T3-L1 adipocytes

(2013) Kyoung Sik Park   CYTOKINE

Eucommia ulmoides Oliv.: Ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine

(2013) Xirui He et al.   JOURNAL OF ETHNOPHARMACOLOGY

A neutrophil elastase inhibitor prevents bleomycin-induced pulmonary fibrosis in mice

(2012) Akihiro Takemasa et al.   EUROPEAN RESPIRATORY JOURNAL

Modeling pulmonary fibrosis with bleomycin

(2011) Marios A. Mouratis et al.   CURRENT OPINION IN PULMONARY MEDICINE

Integrating mechanisms of pulmonary fibrosis

(2011) Thomas A. Wynn   JOURNAL OF EXPERIMENTAL MEDICINE

Potential Therapeutic Targets for Cardiac Fibrosis

(2010) Andrew Leask   CIRCULATION RESEARCH

ANTIPROLIFERATIVE ACTIVITY OF AUCUBIN IS THROUGH CELL CYCLE ARREST AND APOPTOSIS IN HUMAN NON-SMALL CELL LUNG CANCER A549 CELLS

(2008) Jen-Yu Hung et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY