Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking

IL-10 Plays Opposing Roles duringStaphylococcus aureusSystemic and Localized Infections

(2017) John M. Leech et al.   JOURNAL OF IMMUNOLOGY

Selenium inhibits Staphylococcus aureus -induced inflammation by suppressing the activation of the NF-κB and MAPK signalling pathways in RAW264.7 macrophages

(2016) Chong-Liang Bi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neutralization of MMP-2 protects Staphylococcus aureus infection induced septic arthritis in mice and regulates the levels of cytokines

(2016) Sahin Sultana et al.   MICROBIAL PATHOGENESIS

The c-Jun N-terminal kinase (JNK) pathway is activated in human interstitial cystitis (IC) and rat protamine sulfate induced cystitis

(2016) Jiang Zhao et al.   Scientific Reports

TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis

(2016) Xin Chen et al.   Scientific Reports

Effect of exogenous MCP-1 on TLR-2 neutralized murine macrophages and possible mechanisms of CCR-2/TLR-2 and MCP-1 signalling during Staphylococcus aureus infection

(2015) Biswadev Bishayi et al.   IMMUNOBIOLOGY

TRAF-mediated modulation of NF-kB AND JNK Activation by TNFR2

(2014) Lucía Cabal-Hierro et al.   CELLULAR SIGNALLING

IFN- -Induced TNF-  Expression Is Regulated by Interferon Regulatory Factors 1 and 8 in Mouse Macrophages

(2014) V. Vila-del Sol et al.   JOURNAL OF IMMUNOLOGY

Septic arthritis: immunopathogenesis, experimental models and therapy

(2014) Priscila Colavite et al.   JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES

Selective Tumor Necrosis Factor Receptor I Blockade Is Antiinflammatory and Reveals Immunoregulatory Role of Tumor Necrosis Factor Receptor II in Collagen-Induced Arthritis

(2014) Fiona E. McCann et al.   Arthritis & Rheumatology

Antibiotic-KilledStaphylococcus aureusInduces Destructive Arthritis in Mice

(2014) Abukar Ali et al.   Arthritis & Rheumatology

Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation

(2013) Elaine Hatanaka et al.   PLoS One

Endogenous Myeloperoxidase Is a Mediator of Joint Inflammation and Damage in Experimental Arthritis

(2013) Dragana Odobasic et al.   Arthritis & Rheumatology

Azithromycin in combination with riboflavin decreases the severity of Staphylococcus aureus infection induced septic arthritis by modulating the production of free radicals and endogenous cytokines

(2012) Pinky Mal et al.   INFLAMMATION RESEARCH

Targeting TNF receptors in rheumatoid arthritis

(2012) S. Bluml et al.   INTERNATIONAL IMMUNOLOGY

Staphylococcus aureus Protein A Plays a Critical Role in Mediating Bone Destruction and Bone Loss in Osteomyelitis

(2012) Amro Widaa et al.   PLoS One

Gentamicin in Combination with Ascorbic Acid Regulates the severity ofStaphylococcus aureusInfection-Induced Septic Arthritis in Mice

(2012) P. Mal et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Risk of septic arthritis in patients with rheumatoid arthritis and the effect of anti-TNF therapy: results from the British Society for Rheumatology Biologics Register

(2011) J. B. Galloway et al.   ANNALS OF THE RHEUMATIC DISEASES

Contribution of matrix metalloproteinase 2 to joint destruction in group BStreptococcus-induced murine arthritis

(2011) Manuela Puliti et al.   ARTHRITIS AND RHEUMATISM

Tumor necrosis factor receptor cross-talk

(2011) Petrus J. W. Naudé et al.   FEBS Journal

Mitochondrial c-Jun N-terminal Kinase (JNK) Signaling Initiates Physiological Changes Resulting in Amplification of Reactive Oxygen Species Generation

(2011) Jeremy W. Chambers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adjuvant Anti-Tumor Necrosis Factor Therapy for Staphylococcal Arthritis and Sepsis: A Cautionary Note

(2011) A. W. Chow   JOURNAL OF INFECTIOUS DISEASES

The Combination of a Tumor Necrosis Factor Inhibitor and Antibiotic Alleviates Staphylococcal Arthritis and Sepsis in Mice

(2011) Ying Fei et al.   JOURNAL OF INFECTIOUS DISEASES

TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α

(2011) Leslie A Bruggeman et al.   LABORATORY INVESTIGATION

Antiinflammatory effects of tumor necrosis factor on hematopoietic cells in a murine model of erosive arthritis

(2010) Stephan Blüml et al.   ARTHRITIS AND RHEUMATISM

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Role of nitric oxide produced by iNOS through NF-κB pathway in migration of cerebellar granule neurons induced by Lipopolysaccharide

(2010) Daniela Arias-Salvatierra et al.   CELLULAR SIGNALLING

Biological role of matrix metalloproteinases: a critical balance

(2010) S. Loffek et al.   EUROPEAN RESPIRATORY JOURNAL

Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways

(2010) Caterina Veroni et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy

(2009) H. Li et al.   HUMAN MOLECULAR GENETICS

Interaction of staphylococci with bone

(2009) John A. Wright et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo

(2009) Stefania Momi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases

(2008) Bruce Beutler   IMMUNOLOGICAL REVIEWS

IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-  and IL-17

(2008) M. Hashizume et al.   RHEUMATOLOGY