Article
Chemistry, Multidisciplinary
Jie Shen, R. Deepa, Zhongyan Li, Hyeonji Oh, Harekrushna Behera, Himanshu Joshi, Manish Kumar, Aleksei Aksimentiev, Huaqiang Zeng
Summary: Unlike many other biologically relevant ions, lithium concentrations can vary greatly and there are no specific lithium channel proteins. While natural pathways involve competing with sodium ions, developing artificial lithium-transporting channels is challenging. This study demonstrates that sulfur-containing organic nanotubes derived from helically folded aromatic foldamers can selectively and efficiently transport lithium ions across membranes, with high selectivity over sodium and potassium ions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Ying-Jie Liu, Yu Liu, Shuang-Quan Zang
Summary: In this study, we successfully constructed a solvation-mediated self-assembly of single-crystals to helical nanofibers driven by protic acyclic (methoxy)(amino)carbenes (pAMACs) Au-I-enantiomers. The aggregation-dependent thermally activated delayed fluorescence properties were found to be attributed to packing modes of Au dimers and chains. Furthermore, the formation of extended helical Au molecular chains amplified supramolecular chirality, leading to strong CPL performance.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Wanru Gao, Yuping Li, Yunping Zhoujin, Qun Zeng, Liwen Fang, Sean Parkin, Tonglei Li, Shigang Ruan, Sihui Long
Summary: Four 2-hydroxy-N-alkyl-N-phenyl-nicotinamides were synthesized and their crystal structures were analyzed to investigate the effect of substitution on the crystal packing. The molecules were found to be in the keto form and exhibited a peptoid-like structure. Experimental and theoretical calculations provided a reasonable explanation for the formation of the keto tautomer and the hydrates.
Article
Chemistry, Multidisciplinary
Andrew J. Bennett, Adam J. Matzger
Summary: In contrast to neutral cocrystals, designing ionic cocrystals, especially those with an ion pair, is challenging. Previous studies that correlate specific molecular properties to cocrystal formation generally exclude ionic cocrystals, leaving few clear avenues to success for prospective ionic cocrystal engineers. In this study, ammonium nitrate was targeted for cocrystallization with a potential coformer group selected based on likely interactions with the nitrate ion. Six novel ionic cocrystals were discovered, and a high packing coefficient was found to be a consistent feature among successful coformers.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Qishuo Zhong, Yin Cao, Xiaopan Xie, Yuhang Wu, Zhiqing Chen, Qiuping Zhang, Chunyan Jia, Zhen Wu, Pengyang Xin, Xiaosheng Yan, Zhiping Zeng, Changliang Ren
Summary: This study introduces a novel artificial channel that can disrupt the ion homeostasis of cancer cells with high selectivity by activation with biocompatible visible light. The channel enhances cytotoxicity against human colorectal cancer cells and involves multiple cell death pathways. Additionally, the channel exhibits minimal toxicity towards normal cells.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Materials Science, Multidisciplinary
Lucile Fauvre, Etienne Fleury, Francois Ganachaud, Daniel Portinha
Summary: Silicone elastomers with self-associating bisamide groups were synthesized by aza-Michael addition, leading to linear polymers or branched polymers depending on the molar ratios of reactive functions. The amide groups in the polymers develop H-bond interactions, resulting in phase-separated domains and altered rheological and viscoelastic properties. Increasing the molecular weight of the polymers transforms them from viscoelastic liquids to viscoelastic solids and elastomers, with the latter exhibiting self-healing propensity at room temperature.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Lucile Fauvre, Etienne Fleury, Francois Ganachaud, Daniel Portinha
Summary: Silicone elastomers with self-associating bisamide groups were synthesized using aza-Michael addition. Non-crosslinked copolymers were prepared by adjusting the molar ratio of vinyl to primary amine reactive function. By increasing the molecular weight, the copolymers transformed from viscoelastic liquids to viscoelastic solids and elastomers.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Nans Roques, Anthony Tovar-Molle, Carine Duhayon, Stephane Brandes, Alex Spiess, Christoph Janiak, Jean-Pascal Sutter
Summary: Five isostructural microporous supramolecular architectures with different R groups were obtained by H-bonded assembly, and a three-component H-bonded porous framework was successfully achieved using a mixture of tripodal cations with different R groups. The materials have pore diameters ranging from 3.0 to 8.5 angstrom and the sorption properties are influenced by the R groups.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Physical
Sourav Dutta, Debabrata Mandal
Summary: The 2P3HBQ and 2HP3HBQ fluorophores exhibit well-separated dual emission peaks due to Excited State Intramolecular Proton Transfer (ESIPT), with unusually long time-constants suggesting intermolecular H-bonding with the solvent. Temperature-dependent fluorescence studies show that ESIPT rates vary significantly with temperature, indicating the prevalence of solvent fluorophore intermolecular H-bonding. ESIPT observed in the gel state differs from that in the solution state, indicating the effect of confinement on the photophysics of the gel-bound fluorophores.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Multidisciplinary
Georgia C. Zimmer, Anderson B. Pagliari, Vanessa B. Solner, Manfredo Horner, Helio G. Bonacorso, Nilo Zanatta, Marcos A. P. Martins
Summary: Insights are presented into the occurrence of packing polymorphs and conformational polymorphs of 1,2-bis(aminocarbonyl(1-tert-butyl-1H-pyrazol-[3]5-yl))ethanes with different substituents. Different molecular forms, including linear and folded, were observed, each with distinct stacking interactions and stability. The presence of NH···O=C bonds and water binding were found to play significant roles in the formation and stability of different polymorphs.
CRYSTAL GROWTH & DESIGN
(2021)
Article
Chemistry, Multidisciplinary
Kun Zhang, Aiqin Yu, Xuan Chu, Fudong Li, Juan Liu, Lin Liu, Wen-Ju Bai, Chao He, Xiqing Wang
Summary: Selective hydroxylation of non-activated aliphatic C-H bonds was achieved through directed evolution of P450(BS beta) hydroxylase. The reaction showed high selectivity towards various aliphatic carboxylic acids with different chain lengths, functional groups, and aromatic moieties. The X-ray structure of the evolved enzyme variant provided insights into the regio- and enantioselectivity of the reaction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Biochemistry & Molecular Biology
Matienko Ludmila, Zhigacheva Irina, Mil Elena, Albantova Anastasia, Goloshchapov Alexander
Summary: This article discusses the role of ligands in regulating the catalytic activity of Ni-complexes in the green process of selective ethylbenzene oxidation. The dual function of phenol in the coordination sphere of the nickel complex as an antioxidant or catalyst depends on the ligand environment. The role of intermolecular H-bonds and supramolecular structures in selective catalysis by nickel complexes in chemical and biological oxidation reactions is analyzed.
Article
Chemistry, Physical
Andrzej Nowok, Karolina Jurkiewicz, Mateusz Dulski, Hubert Hellwig, Jan G. Malecki, Katarzyna Grzybowska, Joanna Grelska, Sebastian Pawlus
Summary: The molecular architecture of 1-phenyl alcohols has a significant impact on their glass transition temperature, molecular dynamics, and hydrogen bond strength, as well as the morphology of the supramolecular clusters formed by the linked molecules.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Multidisciplinary
David Maurer, Bernhard Breit
Summary: A new air-stable and conveniently crystallizable Rh-III-cyclopentadienyl catalyst substituted with a urea moiety has been designed and synthesized, accelerating the C-H olefination of benzoic acid derivatives. The substrate recognition ability mediated by hydrogen bonding and the introduction of pyridone-phosphine ligands have enhanced the catalytic performance. By revealing a relation between reaction rate and relative complex formation enthalpy, the hypothesis of supramolecular catalyst preformation was supported, leading to improved yields compared to traditional catalysts.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Multidisciplinary Sciences
Alexander A. Bredikhin, Aidar T. Gubaidullin, Zemfira A. Bredikhina, Robert R. Fayzullin, Olga A. Lodochnikova
Summary: Chiral recognition is crucial for the self-assembly of soft materials, particularly supramolecular organogels formed by low molecular weight gelators. This study identified seven different types of supramolecular motifs among the samples studied, with only two realized in crystals of supramolecular gelators. The ability to form gels was attempted to be related to the characteristics of the supramolecular motif of a potential gelling agent and the chiral characteristics of the sample.