Synonymous Somatic Variants in Human Cancer Are Not Infamous: A Plea for Full Disclosure in Databases and Publications

Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility

(2016) Richarda M. de Voer et al.   PLoS Genetics

Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling

(2015) Ulrike Friedrich et al.   HUMAN MOLECULAR GENETICS

Intron retention is a widespread mechanism of tumor-suppressor inactivation

(2015) Hyunchul Jung et al.   NATURE GENETICS

The functional relevance of somatic synonymous mutations in melanoma and other cancers

(2015) Valer Gotea et al.   Pigment Cell & Melanoma Research

Discrepancies in Cancer Genomic Sequencing Highlight Opportunities for Driver Mutation Discovery

(2014) A. M. Hudson et al.   CANCER RESEARCH

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

(2014) Fran Supek et al.   CELL

Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

(2014) Bernard Leroy et al.   HUMAN MUTATION

TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade

(2014) Bernard Leroy et al.   HUMAN MUTATION

The silent codon change I507-ATC→ATT contributes to the severity of the ΔF508 CFTR channel dysfunction

(2013) Ahmed Lazrak et al.   FASEB JOURNAL

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

(2013) J. J. Gartner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hidden Codes That Shape Protein Evolution

(2013) R. J. Weatheritt et al.   SCIENCE

Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution

(2013) A. B. Stergachis et al.   SCIENCE

Integrated analysis of recurrent properties of cancer genes to identify novel drivers

(2013) Matteo D'Antonio et al.   GENOME BIOLOGY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Data Sharing in the Post-Genomic World: The Experience of the International Cancer Genome Consortium (ICGC) Data Access Compliance Office (DACO)

(2012) Yann Joly et al.   PLoS Computational Biology

A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients

(2011) Paola Griseri et al.   HUMAN MOLECULAR GENETICS

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

Understanding the contribution of synonymous mutations to human disease

(2011) Zuben E. Sauna et al.   NATURE REVIEWS GENETICS

Genomics and the Continuum of Cancer Care

(2011) Ultan McDermott et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alternative splicing: good and bad effects of translationally silent substitutions

(2010) M. Raponi et al.   FEBS Journal

A Synonymous Single Nucleotide Polymorphism in ΔF508CFTRAlters the Secondary Structure of the mRNA and the Expression of the Mutant Protein

(2010) Rafal A. Bartoszewski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silent mutations in sight: co-variations in tRNA abundance as a key to unravel consequences of silent mutations

(2010) Andreas Czech et al.   Molecular BioSystems

Two silent substitutions in the PDHA1 gene cause exon 5 skipping by disruption of a putative exonic splicing enhancer

(2007) A. Boichard et al.   MOLECULAR GENETICS AND METABOLISM