High-throughput screening uncovers miRNAs enhancing glioblastoma cell susceptibility to tyrosine kinase inhibitors

Cell-based therapy using miR-302-367 expressing cells represses glioblastoma growth

(2017) Mohamed Fareh et al.   Cell Death & Disease

MiR-520b as a novel molecular target for suppressing stemness phenotype of head-neck cancer by inhibiting CD44

(2017) Ya-Ching Lu et al.   Scientific Reports

Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma

(2016) Wei Wei et al.   CANCER CELL

Randomized phase II study of axitinib versus physicians best alternative choice of therapy in patients with recurrent glioblastoma

(2016) J. Duerinck et al.   JOURNAL OF NEURO-ONCOLOGY

MicroRNA-302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

(2016) Jiuhong Ma et al.   ONCOLOGY REPORTS

Phase II evaluation of sunitinib in the treatment of recurrent or refractory high-grade glioma or ependymoma in children: a children's Oncology Group Study ACNS1021

(2016) Cynthia Wetmore et al.   Cancer Medicine

MicroRNAs in Glioblastoma: Role in Pathogenesis and Opportunities for Targeted Therapies

(2015) Pedro Costa et al.   CNS & Neurological Disorders-Drug Targets

Expression of the miR-302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes

(2015) Chul Min Yang et al.   INTERNATIONAL JOURNAL OF CANCER

MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma

(2015) Pedro M. Costa et al.   JOURNAL OF CONTROLLED RELEASE

DIANA-miRPath v3.0: deciphering microRNA function with experimental support

(2015) Ioannis S. Vlachos et al.   NUCLEIC ACIDS RESEARCH

FDA-approved small-molecule kinase inhibitors

(2015) Peng Wu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

MicroRNA-520b affects the proliferation of human glioblastoma cells by directly targeting cyclin D1

(2015) Xuchang Liu et al.   TUMOR BIOLOGY

MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras

(2014) Zhumei Shi et al.   NEURO-ONCOLOGY

Feedback and redundancy in receptor tyrosine kinase signaling: relevance to cancer therapies

(2014) Chong Sun et al.   TRENDS IN BIOCHEMICAL SCIENCES

Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway

(2013) Howard A. Burris   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Dose-Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial

(2013) Mark R. Gilbert et al.   JOURNAL OF CLINICAL ONCOLOGY

High-Dose Crizotinib for Brain Metastases Refractory to Standard-Dose Crizotinib

(2013) Young Hak Kim et al.   Journal of Thoracic Oncology

The integrated landscape of driver genomic alterations in glioblastoma

(2013) Veronique Frattini et al.   NATURE GENETICS

MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells

(2013) Pierpaolo Peruzzi et al.   NEURO-ONCOLOGY

DIANA-microT web server v5.0: service integration into miRNA functional analysis workflows

(2013) Maria D. Paraskevopoulou et al.   NUCLEIC ACIDS RESEARCH

miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma

(2013) L. K. Mathew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CPEB1, a histone-modified hypomethylated gene, is regulated by miR-101 and involved in cell senescence in glioma

(2013) L Xiaoping et al.   Cell Death & Disease

De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients

(2013) David Akhavan et al.   Cancer Discovery

Functional microRNA targets in protein coding sequences

(2012) Martin Reczko et al.   BIOINFORMATICS

MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma

(2012) Pedro M. Costa et al.   HUMAN MOLECULAR GENETICS

The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1

(2012) N. Cai et al.   RNA

Current concepts and management of glioblastoma

(2011) Matthias Preusser et al.   ANNALS OF NEUROLOGY

Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma

(2011) Matija Snuderl et al.   CANCER CELL

Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors

(2011) Arkaitz Carracedo et al.   CELL CYCLE

The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network

(2011) M Fareh et al.   CELL DEATH AND DIFFERENTIATION

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells

(2011) Deepa Subramanyam et al.   NATURE BIOTECHNOLOGY

"Pulsatile" high-dose weekly erlotinib for CNS metastases from EGFR mutant non-small cell lung cancer

(2011) C. Grommes et al.   NEURO-ONCOLOGY

MiR-135a functions as a selective killer of malignant glioma

(2011) S Wu et al.   ONCOGENE

Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases

(2011) T Papagiannakopoulos et al.   ONCOGENE

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Multiple microRNAs rescue from Ras-induced senescence by inhibiting p21Waf1/Cip1

(2010) V Borgdorff et al.   ONCOGENE

Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3′ untranslated region

(2010) S Wu et al.   ONCOGENE

Randomized Phase II Trial of Chemoradiotherapy Followed by Either Dose-Dense or Metronomic Temozolomide for Newly Diagnosed Glioblastoma

(2009) Jennifer L. Clarke et al.   JOURNAL OF CLINICAL ONCOLOGY

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

(2009) Athanasia Spandidos et al.   NUCLEIC ACIDS RESEARCH

Oct4/Sox2-Regulated miR-302 Targets Cyclin D1 in Human Embryonic Stem Cells

(2008) D. A. Greer Card et al.   MOLECULAR AND CELLULAR BIOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE