Mice lacking cyclin-dependent kinase-like 5 manifest autistic and ADHD-like behaviors

Searching for biomarkers of CDKL5 disorder: early-onset visual impairment in CDKL5 mutant mice

(2017) Raffaele Mazziotti et al.   HUMAN MOLECULAR GENETICS

Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1

(2016) Grazia Della Sala et al.   BIOLOGICAL PSYCHIATRY

ADHD in childhood epilepsy: Clinical determinants of severity and of the response to methylphenidate

(2016) Sylvain Rheims et al.   EPILEPSIA

Attention deficit hyperactivity disorder

(2016) Anita Thapar et al.   LANCET

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c

(2016) Yi-Chuan Chen et al.   NATURE NEUROSCIENCE

Phasic dopamine release in the medial prefrontal cortex enhances stimulus discrimination

(2016) Andrei T. Popescu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autism, DRD3 and repetitive and stereotyped behavior, an overview of the current knowledge

(2015) Wouter G. Staal   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Social Novelty Investigation in the Juvenile Rat: Modulation by the μ-Opioid System

(2015) C. J. W. Smith et al.   JOURNAL OF NEUROENDOCRINOLOGY

MeCP2 in the Rostral Striatum Maintains Local Dopamine Content Critical for Psychomotor Control

(2015) San-Hua Su et al.   JOURNAL OF NEUROSCIENCE

Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder

(2015) Claudia Fuchs et al.   NEUROBIOLOGY OF DISEASE

Everyday executive function impairments predict comorbid psychopathology in autism spectrum and attention deficit hyperactivity disorders.

(2015) Rachel A. Lawson et al.   NEUROPSYCHOLOGY

Prevalence of Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis

(2015) R. Thomas et al.   PEDIATRICS

The role of ultrasonic vocalizations in mouse communication

(2014) Christine V Portfors et al.   CURRENT OPINION IN NEUROBIOLOGY

Brain γ-aminobutyric acid: a neglected role in impulsivity

(2014) Dave J. Hayes et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward

(2014) Yijun Cui et al.   NATURE NEUROSCIENCE

Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling

(2014) Claudia Fuchs et al.   NEUROBIOLOGY OF DISEASE

Mapping Pathological Phenotypes in a Mouse Model of CDKL5 Disorder

(2014) Elena Amendola et al.   PLoS One

The effects of vasopressin deficiency on aggression and impulsiveness in male and female rats

(2014) Anna Fodor et al.   PSYCHONEUROENDOCRINOLOGY

Dysfunctional dopaminergic neurotransmission in asocial BTBR mice

(2014) M Squillace et al.   Translational Psychiatry

MeCP2-mediated alterations of striatal features accompany psychomotor deficits in a mouse model of Rett syndrome

(2013) Fang-Chi Kao et al.   Brain Structure & Function

De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder

(2013) P J Hamilton et al.   MOLECULAR PSYCHIATRY

Corticostriatal connectivity and its role in disease

(2013) Gordon M. G. Shepherd   NATURE REVIEWS NEUROSCIENCE

Diminished FoxP2 Levels Affect Dopaminergic Modulation of Corticostriatal Signaling Important to Song Variability

(2013) Malavika Murugan et al.   NEURON

Palmitoylation-dependent CDKL5-PSD-95 interaction regulates synaptic targeting of CDKL5 and dendritic spine development

(2013) Y.-C. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Human Language-Associated Gene SRPX2 Regulates Synapse Formation and Vocalization in Mice

(2013) G. M. Sia et al.   SCIENCE

Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

(2013) E. Burguiere et al.   SCIENCE

Repeated Cortico-Striatal Stimulation Generates Persistent OCD-Like Behavior

(2013) S. E. Ahmari et al.   SCIENCE

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1–PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons

(2012) Sara Ricciardi et al.   NATURE CELL BIOLOGY

Whole-Brain Mapping of Direct Inputs to Midbrain Dopamine Neurons

(2012) Mitsuko Watabe-Uchida et al.   NEURON

Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice

(2012) I.-T. J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FOXP2 and the role of cortico-basal ganglia circuits in speech and language evolution

(2011) Wolfgang Enard   CURRENT OPINION IN NEUROBIOLOGY

Exclusive and common targets of neostriatofugal projections of rat striosome neurons: a single neuron-tracing study using a viral vector

(2011) Fumino Fujiyama et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Regulation of MET by FOXP2, Genes Implicated in Higher Cognitive Dysfunction and Autism Risk

(2011) Z. Mukamel et al.   JOURNAL OF NEUROSCIENCE

Nucleus Accumbens  -Opioid Receptors Mediate Social Reward

(2011) V. Trezza et al.   JOURNAL OF NEUROSCIENCE

Ameliorative effect of Yokukansan on social isolation-induced aggressive behavior of zinc-deficient young mice

(2010) Haruna Tamano et al.   BRAIN RESEARCH BULLETIN

CDKL5, a Protein Associated with Rett Syndrome, Regulates Neuronal Morphogenesis via Rac1 Signaling

(2010) Q. Chen et al.   JOURNAL OF NEUROSCIENCE

The Neuropsychopharmacology of Fronto-Executive Function: Monoaminergic Modulation

(2009) T.W. Robbins et al.   Annual Review of Neuroscience

A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice

(2009) Wolfgang Enard et al.   CELL

Dopamine Receptor D1/D5 Gene Expression in the Medial Prefrontal Cortex Predicts Impulsive Choice in Rats

(2009) Maarten Loos et al.   CEREBRAL CORTEX

Dopamine transporter gene variation modulates activation of striatum in youth with ADHD

(2009) Anne-Claude Bédard et al.   NEUROIMAGE

Partial ablation of mu-opioid receptor rich striosomes produces deficits on a motor-skill learning task

(2009) C. Lawhorn et al.   NEUROSCIENCE

FOXP2 as a molecular window into speech and language

(2009) Simon E. Fisher et al.   TRENDS IN GENETICS

A Common Variant in DRD3 Receptor Is Associated with Autism Spectrum Disorder

(2008) Mariken de Krom et al.   BIOLOGICAL PSYCHIATRY

CDKL5 Expression Is Modulated during Neuronal Development and Its Subcellular Distribution Is Tightly Regulated by the C-terminal Tail

(2008) Laura Rusconi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-occurrence of Motor Problems and Autistic Symptoms in Attention-Deficit/Hyperactivity Disorder

(2008) ANGELA M. REIERSEN et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Ultrasonic vocalizations: A tool for behavioural phenotyping of mouse models of neurodevelopmental disorders

(2008) Maria Luisa Scattoni et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A Functional Genetic Link between Distinct Developmental Language Disorders

(2008) Sonja C. Vernes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modular patterning of structure and function of the striatum by retinoid receptor signaling

(2008) W.-L. Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells

(2008) E. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

(2008) S. Jamain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA