Regulatory T-cell conditioning endows activated effector T cells with suppressor function in autoimmune hepatitis/autoimmune sclerosing cholangitis

Dysfunction of hepatic regulatory T cells in experimental sclerosing cholangitis is related to IL-12 signaling

(2017) Dorothee Schwinge et al.   JOURNAL OF HEPATOLOGY

CD39 mediated regulation of Th17-cell effector function is impaired in juvenile autoimmune liver disease

(2016) Rodrigo Liberal et al.   JOURNAL OF AUTOIMMUNITY

Expanding antigen-specific regulatory networks to treat autoimmunity

(2016) Xavier Clemente-Casares et al.   NATURE

In autoimmune hepatitis type 1 or the autoimmune hepatitis-sclerosing cholangitis variant defective regulatory T-cell responsiveness to IL-2 results in low IL-10 production and impaired suppression

(2015) Rodrigo Liberal et al.   HEPATOLOGY

Systems biologic analysis of T regulatory cells genetic pathways in murine primary biliary cirrhosis

(2015) Yin-Hu Wang et al.   JOURNAL OF AUTOIMMUNITY

Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation

(2015) Nicola Gagliani et al.   NATURE

Reduced FOXP3+ regulatory T cells in patients with primary sclerosing cholangitis are associated with IL2RA gene polymorphisms

(2014) Marcial Sebode et al.   JOURNAL OF HEPATOLOGY

Dysfunctional CD39POSregulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis

(2013) Charlotte R. Grant et al.   HEPATOLOGY

Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells

(2013) Nicola Gagliani et al.   NATURE MEDICINE

Inhibition of Interleukin-17 Promotes Differentiation of CD25– Cells Into Stable T Regulatory Cells in Patients With Autoimmune Hepatitis

(2012) Maria Serena Longhi et al.   GASTROENTEROLOGY

Identification of a human Th1-like IFNγ-secreting Treg subtype deriving from effector T cells

(2012) Ram Kumar Chowdary Venigalla et al.   JOURNAL OF AUTOIMMUNITY

Interleukin-7 matures suppressive CD127+ forkhead box P3 (FoxP3)+ T cells into CD127- CD25high FoxP3+ regulatory T cells

(2011) V. Di Caro et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD2 Costimulation Reveals Defective Activity by Human CD4+CD25hi Regulatory Cells in Patients with Multiple Sclerosis

(2011) C. M. Baecher-Allan et al.   JOURNAL OF IMMUNOLOGY

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

(2011) Margarita Dominguez-Villar et al.   NATURE MEDICINE

Autoimmune hepatitis

(2011) Giorgina Mieli-Vergani et al.   Nature Reviews Gastroenterology & Hepatology

Interleukin-17 Contributes to the Pathogenesis of Autoimmune Hepatitis through Inducing Hepatic Interleukin-6 Expression

(2011) Li Zhao et al.   PLoS One

Deficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis

(2008) Weici Zhang et al.   HEPATOLOGY