The physiological roles of apolipoprotein J/clusterin in metabolic and cardiovascular diseases

Ambient ultrafine particles reduce endothelial nitric oxide production via S-glutathionylation of eNOS

(2013) Yunfeng Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice

(2013) Zhuofeng Lin et al.   Cell Metabolism

Altered Activation of Endothelial Anti- and Proapoptotic Pathways by High-Density Lipoprotein from Patients with Coronary Artery Disease

(2013) Meliana Riwanto et al.   CIRCULATION

Clusterin Decreases Hepatic SREBP-1c Expression and Lipid Accumulation

(2013) Hye-Young Seo et al.   ENDOCRINOLOGY

Expression ofCluandTgfb1during murine tooth development: effects of in-vivo transfection with anti-miR-214

(2013) Qalb-E-Saleem Khan et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Allele-Specific Expression of Angiotensinogen in Human Subcutaneous Adipose Tissue

(2013) Sungmi Park et al.   HYPERTENSION

Clusterin Protects Hepatocellular Carcinoma Cells from Endoplasmic Reticulum Stress Induced Apoptosis through GRP78

(2013) Cun Wang et al.   PLoS One

Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway

(2013) So Young Gil et al.   Nature Communications

Protective role of clusterin in preserving endothelial function in AL amyloidosis

(2012) Daniel A. Franco et al.   ATHEROSCLEROSIS

Clusterin inhibition using OGX-011 synergistically enhances antitumour activity of sorafenib in a human renal cell carcinoma model

(2012) Y Kususda et al.   BRITISH JOURNAL OF CANCER

Proteotoxic stress and circulating cell stress proteins in the cardiovascular diseases

(2012) Brian Henderson et al.   CELL STRESS & CHAPERONES

Glucose-Regulated Protein 78 (GRP78) Mediated the Efficacy to Curcumin Treatment on Hepatocellular Carcinoma

(2011) Yu-Jia Chang et al.   ANNALS OF SURGICAL ONCOLOGY

Proteomic analysis of intra-arterial thrombus secretions reveals a negative association of clusterin and thrombospondin-1 with abdominal aortic aneurysm

(2011) Joseph V. Moxon et al.   ATHEROSCLEROSIS

Interaction of a putative BH3 domain of clusterin with anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy

(2011) Dong-Hwa Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SREBP-1c regulates glucose-stimulated hepatic clusterin expression

(2011) Gukhan Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation

(2011) Shannon M. Harlan et al.   CIRCULATION RESEARCH

Randomized Phase II Trial of Custirsen (OGX-011) in Combination with Docetaxel or Mitoxantrone as Second-line Therapy in Patients with Metastatic Castrate-Resistant Prostate Cancer Progressing after First-line Docetaxel: CUOG Trial P-06c

(2011) F. Saad et al.   CLINICAL CANCER RESEARCH

Anti-inflammatory and Antioxidant Properties of HDLs Are Impaired in Type 2 Diabetes

(2011) C. Morgantini et al.   DIABETES

Plasma Clusterin and the Risk of Alzheimer Disease

(2011) Elisabeth M. C. Schrijvers   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Loss of Clusterin Limits Atherosclerosis in Apolipoprotein E-deficient Mice via Reduced Expression of Egr-1 and TNF-α

(2011) Narisato Hamada et al.   Journal of Atherosclerosis and Thrombosis

CRM1 Protein-mediated Regulation of Nuclear Clusterin (nCLU), an Ionizing Radiation-stimulated, Bax-dependent Pro-death Factor

(2011) Konstantin S. Leskov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Impact of Lipoic Acid on Endothelial Function and Proteinuria in Quinapril-Treated Diabetic Patients With Stage I Hypertension

(2011) Syed T. Rahman et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Human nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domain

(2011) Nayoung Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease

(2011) Christian Besler et al.   JOURNAL OF CLINICAL INVESTIGATION

Clusterin Attenuates the Development of Renal Fibrosis

(2011) G.-S. Jung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phase I/II Trial of Custirsen (OGX-011), an Inhibitor of Clusterin, in Combination with a Gemcitabine and Platinum Regimen in Patients with Previously Untreated Advanced Non-small Cell Lung Cancer

(2011) Janessa J. Laskin et al.   Journal of Thoracic Oncology

Apolipoprotein J/Clusterin Is a Novel Structural Component of Human Erythrocytes and a Biomarker of Cellular Stress and Senescence

(2011) Marianna H. Antonelou et al.   PLoS One

Effects of High-Density Lipoproteins on Pancreatic β-Cell Insulin Secretion

(2010) Michelle A. Fryirs et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HDL Apolipoprotein-Related Peptides in the Treatment of Atherosclerosis and other Inflammatory Disorders

(2010) G. S. Getz et al.   CURRENT PHARMACEUTICAL DESIGN

Apolipoprotein A-I Mimetic Peptides Prevent Atherosclerosis Development and Reduce Plaque Inflammation in a Murine Model of Diabetes

(2010) C. Morgantini et al.   DIABETES

Intravenous clusterin administration reduces myocardial infarct size in rats

(2010) Annemieke Van Dijk et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Association of the clusterin gene polymorphisms with type 2 diabetes mellitus

(2010) Makoto Daimon et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Oxidized LDL: Diversity, Patterns of Recognition, and Pathophysiology

(2009) Irena Levitan et al.   ANTIOXIDANTS & REDOX SIGNALING

Protective Role of Clusterin/Apolipoprotein J Against Neointimal Hyperplasia via Antiproliferative Effect on Vascular Smooth Muscle Cells and Cytoprotective Effect on Endothelial Cells

(2009) Han-Jong Kim et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HDL as a Biomarker, Potential Therapeutic Target, and Therapy: FIG. 1.

(2009) Mohamad Navab et al.   DIABETES

Over-expression of clusterin is a resistance factor to the anti-cancer effect of histone deacetylase inhibitors

(2009) Tao Liu et al.   EUROPEAN JOURNAL OF CANCER

Genome-wide association studies in Alzheimer's disease

(2009) L. Bertram et al.   HUMAN MOLECULAR GENETICS

Roles of clusterin in progression, chemoresistance and metastasis of human ovarian cancer

(2009) Li Wei et al.   INTERNATIONAL JOURNAL OF CANCER

Major Lipids, Apolipoproteins, and Risk of Vascular Disease

(2009) The Emerging Risk Factors Collaboration*   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Intracellular Clusterin Inhibits Mitochondrial Apoptosis by Suppressing p53-Activating Stress Signals and Stabilizing the Cytosolic Ku70-Bax Protein Complex

(2008) I. P. Trougakos et al.   CLINICAL CANCER RESEARCH

Clusterin Activates Survival through the Phosphatidylinositol 3-Kinase/Akt Pathway

(2008) Hayet Ammar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

(2008) Catherine Postic et al.   JOURNAL OF CLINICAL INVESTIGATION

The effects of ACE inhibitor and angiotensin receptor blocker on clusterin and apoptosis in the kidney tissue of streptozotocin-diabetic rats

(2008) Matem Tunçdemir et al.   JOURNAL OF MOLECULAR HISTOLOGY

Clusterin, a novel modulator of TGF-β signaling, is involved in Smad2/3 stability

(2007) Kwan-Bok Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS