Metal-free base-mediated oxidative annulation cascades to 3-substituted-3-hydroxyoxindole and its 3-spirocyclic derivative

Ruthenium(0)-Catalyzed C–C Coupling of Alkynes and 3-Hydroxy-2-oxindoles: Direct C–H Vinylation of Alcohols

(2017) Tom Luong et al.   ORGANIC LETTERS

Oxidative Fragmentations and Skeletal Rearrangements of Oxindole Derivatives

(2017) Hendrik F. T. Klare et al.   ORGANIC LETTERS

Synthesis of Functionalized Biaryls and Poly(hetero)aryl Containing Medium-Sized Lactones with Cyclic Diaryliodonium Salts

(2017) Hao Xie et al.   ORGANIC LETTERS

A Tandem Oxidative Annulation Strategy for the Synthesis of Tetracyclic 3-Spirooxindole Benzofuranones

(2017) Chunxia Zhang et al.   ORGANIC LETTERS

Asymmetric Catalytic 1,2-Hydroperoxidation of Isatin-Derived Ketimine with Hydrogen Peroxide in the Crowding Environment of PEGs

(2017) Wengang Guo et al.   ORGANIC LETTERS

PhI(OCOCF3)2-Mediated Construction of a 2-Spiropseudoindoxyl Skeleton via Cascade Annulation of 2-Sulfonamido-N-phenylpropiolamide Derivatives

(2017) Bobo Zhang et al.   ORGANIC LETTERS

Hydroxy-Directed Enantioselective Hydroxyalkylation in the Carbocyclic Ring of Indoles

(2017) Marc Montesinos-Magraner et al.   ORGANIC LETTERS

Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents

(2016) Bin Yu et al.   Anti-Cancer Agents in Medicinal Chemistry

Synthesis of 3-Acetoxyoxindole Derivatives by Metal-Free PhI(OAc)2-Mediated Oxidation of 3-Substituted Indoles

(2016) Liang Wang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Isatin Derived Spirocyclic Analogues with α-Methylene-γ-butyrolactone as Anticancer Agents: A Structure–Activity Relationship Study

(2016) Sandeep Rana et al.   JOURNAL OF MEDICINAL CHEMISTRY

1-Hydroxybenzotriazole-Assisted, N-Heterocyclic Carbene Catalyzed β-Functionalization of Saturated Carboxylic Esters: Access to Spirooxindole Lactones

(2016) Jianfeng Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Aryliodine-Mediated Enantioselective Organocatalytic Spirocyclization: Synthesis of Spirofurooxindoles via Cascade Oxidative C–O and C–C Bond Formation

(2016) Yang Cao et al.   ORGANIC LETTERS

Carbene-catalysed reductive coupling of nitrobenzyl bromides and activated ketones or imines via single-electron-transfer process

(2016) Bao-Sheng Li et al.   Nature Communications

Collective Synthesis and Biological Evaluation of Tryptophan-Based Dimeric Diketopiperazine Alkaloids

(2015) Shinji Tadano et al.   CHEMISTRY-A EUROPEAN JOURNAL

Discovery of orally active anticancer candidate CFI-400945 derived from biologically promising spirooxindoles: Success and challenges

(2015) Bin Yu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

“On water” direct catalytic vinylogous Henry (nitroaldol) reactions of isatins for the efficient synthesis of isoxazole substituted 3-hydroxyindolin-2-ones

(2015) Yong Zhang et al.   GREEN CHEMISTRY

Cu-Catalyzed Cascades to Carbocycles: Union of Diaryliodonium Salts with Alkenes or Alkynes Exploiting Remote Carbocations

(2014) Fengzhi Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A new versatile approach to synthesise enantioenriched 3-hydroxyoxindoles, 1,3-dihydroisobenzofuran and 3-isochromanone derivatives by a rhodium-catalyzed asymmetric arylation–cyclization sequence

(2013) Yi Li et al.   CHEMICAL COMMUNICATIONS

Metal Catalysis versus Organocatalysis in the Catalytic Asymmetric Synthesis of 3-Hydroxyoxindole

(2013) Yunlin Liu et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones

(2012) Renato Dalpozzo et al.   CHEMICAL SOCIETY REVIEWS

Strategies for the enantioselective synthesis of spirooxindoles

(2012) Nicolas R. Ball-Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Catalytic asymmetric synthesis of 3-hydroxyoxindole: a potentially bioactive molecule

(2012) Akshay Kumar et al.   RSC Advances

A Facile Pathway to Enantiomerically Enriched 3-Hydroxy-2-Oxindoles: Asymmetric Intramolecular Arylation of α-Keto Amides Catalyzed by a Palladium-DifluorPhos Complex

(2011) Liang Yin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective methodologies for the synthesis of spiro compounds

(2011) Ramon Rios   CHEMICAL SOCIETY REVIEWS

Nickel-Catalyzed Intramolecular Nucleophilic Addition of Aryl or Vinyl Chlorides to α-Ketoamides Through CCl Bond Activation

(2011) Jin-Xiu Hu et al.   CHEMISTRY-A EUROPEAN JOURNAL

YK-4-279 Inhibits ERG and ETV1 Mediated Prostate Cancer Cell Invasion

(2011) Said Rahim et al.   PLoS One

Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action

(2011) Ke Shen et al.   Chemical Science

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Decarboxylative CH Cross-Coupling of Azoles

(2010) Fengzhi Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Highly Effective One-Pot Synthesis of Quinolines from 2-Alkynylnitrobenzenes

(2010) Kentaro Okuma et al.   HETEROCYCLES

Enantioselective Synthesis of SM-130686 Based on the Development of Asymmetric Cu(I)F Catalysis To Access 2-Oxindoles Containing a Tetrasubstituted Carbon

(2009) Daisuke Tomita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis

(2008) Yi-Xia Jia et al.   CHEMICAL COMMUNICATIONS