Cellular and molecular characterization of IDH1-mutated diffuse low grade gliomas reveals tumor heterogeneity and absence of EGFR/PDGFRα activation

Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice

(2017) Chun-Qing Song et al.   GASTROENTEROLOGY

Diffuse Infiltrating Oligodendroglioma and Astrocytoma

(2017) Martin J. van den Bent et al.   JOURNAL OF CLINICAL ONCOLOGY

SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions

(2017) Wei Sun et al.   JOURNAL OF NEUROSCIENCE

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq

(2017) Andrew S. Venteicher et al.   SCIENCE

Doublecortin in Oligodendrocyte Precursor Cells in the Adult Mouse Brain

(2017) Jenna J. Boulanger et al.   Frontiers in Neuroscience

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

(2016) Michele Ceccarelli et al.   CELL

MicroRNA-105 targets SOX9 and inhibits human glioma cell progression

(2016) Xiyao Liu et al.   FEBS LETTERS

SOX9 drives WNT pathway activation in prostate cancer

(2016) Fen Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

(2016) Itay Tirosh et al.   NATURE

Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas

(2016) Aurélie Kamoun et al.   Nature Communications

Immunotherapy of Malignant Tumors in the Brain: How Different from Other Sites?

(2016) Valérie Dutoit et al.   Frontiers in Oncology

Treatment Strategies for Low-Grade Glioma in Adults

(2016) Nancy Ann Oberheim Bush et al.   Journal of Oncology Practice

SOX9 Overexpression Promotes Glioma Metastasis via Wnt/β-Catenin Signaling

(2015) Hongwei Liu et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion

(2015) Jean-Christophe Larsimont et al.   Cell Stem Cell

Olig1 Acetylation and Nuclear Export Mediate Oligodendrocyte Development

(2015) J. Dai et al.   JOURNAL OF NEUROSCIENCE

EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling

(2015) Feng Liu et al.   MOLECULAR CELL

Mutational landscape and clonal architecture in grade II and III gliomas

(2015) Hiromichi Suzuki et al.   NATURE GENETICS

Integrated genomic characterization of IDH1-mutant glioma malignant progression

(2015) Hanwen Bai et al.   NATURE GENETICS

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance

(2015) Kimmo J. Hatanpaa et al.   NEOPLASIA

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

(2014) Benedikt Wiestler et al.   ACTA NEUROPATHOLOGICA

Co-expression of midkine and pleiotrophin predicts poor survival in human glioma

(2014) Jinyang Ma et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Oncogenic Signaling Is Dominant to Cell of Origin and Dictates Astrocytic or Oligodendroglial Tumor Development from Oligodendrocyte Precursor Cells

(2014) N. Lindberg et al.   JOURNAL OF NEUROSCIENCE

A vaccine targeting mutant IDH1 induces antitumour immunity

(2014) Theresa Schumacher et al.   NATURE

SOX9 Regulates Low Density Lipoprotein Receptor-related Protein 6 (LRP6) and T-cell Factor 4 (TCF4) Expression and Wnt/β-catenin Activation in Breast Cancer

(2013) Hongyun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

(2013) B. E. Johnson et al.   SCIENCE

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

(2013) D. Rohle et al.   SCIENCE

Transcriptional Differences between Normal and Glioma-Derived Glial Progenitor Cells Identify a Core Set of Dysregulated Genes

(2013) Romane M. Auvergne et al.   Cell Reports

Phosphorylated olig1 localizes to the cytosol of oligodendrocytes and promotes membrane expansion and maturation

(2012) Jianqin Niu et al.   GLIA

Pleiotrophin Suppression of Receptor Protein Tyrosine Phosphatase- /  Maintains the Self-Renewal Competence of Fetal Human Oligodendrocyte Progenitor Cells

(2012) C. R. McClain et al.   JOURNAL OF NEUROSCIENCE

Asymmetry-Defective Oligodendrocyte Progenitors Are Glioma Precursors

(2011) Sista Sugiarto et al.   CANCER CELL

An EGFR-ERK-SOX9 Signaling Cascade Links Urothelial Development and Regeneration to Cancer

(2011) S. Ling et al.   CANCER RESEARCH

The origins of glioma: E Pluribus Unum?

(2011) F. A. Siebzehnrubl et al.   GLIA

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

Molecular diagnostics of gliomas: state of the art

(2010) Markus J. Riemenschneider et al.   ACTA NEUROPATHOLOGICA

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

(2010) Houtan Noushmehr et al.   CANCER CELL

EGFR immunolabeling pattern may discriminate low-grade gliomas from gliosis

(2010) Fanny Burel-Vandenbos et al.   JOURNAL OF NEURO-ONCOLOGY

Pyramidal Neurons Are Generated from Oligodendroglial Progenitor Cells in Adult Piriform Cortex

(2010) F. Guo et al.   JOURNAL OF NEUROSCIENCE

IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas

(2010) C. Houillier et al.   NEUROLOGY

The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas

(2010) Lee A. D. Cooper et al.   PLoS One

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

(2008) Akiko Nishiyama et al.   NATURE REVIEWS NEUROSCIENCE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE