Aging and radiation: bad companions

Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories

(2014) Jordi Camps et al.   FASEB JOURNAL

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

p53mutations associated with aging-related rise in cancer incidence rates

(2013) Richard B Richardson   CELL CYCLE

DNA Damage Triggers a Chronic Autoinflammatory Response, Leading to Fat Depletion in NER Progeria

(2013) Ismene Karakasilioti et al.   Cell Metabolism

Charity begins at home: non-coding RNA functions in DNA repair

(2013) Dipanjan Chowdhury et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Increased Mammogram-Induced DNA Damage in Mammary Epithelial Cells Aged In Vitro

(2013) Laia Hernández et al.   PLoS One

Oxidative stress and cancer: An overview

(2012) Venus Sosa et al.   AGEING RESEARCH REVIEWS

Lamins as mediators of oxidative stress

(2012) Tom Sieprath et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Non homologous end joining-mediated DNA break repair is impaired in B lymphocytes of aging mice

(2012) Abdul Gafoor Puthiyaveetil et al.   MOLECULAR IMMUNOLOGY

Telomere fusions in early human breast carcinoma

(2012) H. Tanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence

(2012) Z. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain

(2012) J. N. Savas et al.   SCIENCE

Antioxidant Protection against Curative and Palliative Doses of Ionizing Irradiation in Human Blood Decreases with Aging

(2012) Jelena Kasapović et al.   TheScientificWorldJOURNAL

Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation

(2011) Vanja Pekovic et al.   AGING CELL

Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice

(2011) L. Li et al.   BLOOD

The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis

(2011) Xuefeng Fang et al.   BMC GENOMICS

A dual role for A-type lamins in DNA double-strand break repair

(2011) Abena B. Redwood et al.   CELL CYCLE

Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration

(2011) Aristidis S. Veskoukis et al.   CELL STRESS & CHAPERONES

Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts

(2011) Kan Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

The DNA Damage Response Induces IFN

(2011) Sabrina Brzostek-Racine et al.   JOURNAL OF IMMUNOLOGY

Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression

(2011) T Lushnikova et al.   ONCOGENE

Accumulation of DNA Damage in Hematopoietic Stem and Progenitor Cells during Human Aging

(2011) Claudia E. Rübe et al.   PLoS One

p53, Oxidative Stress, and Aging

(2010) Dongping Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

(2010) Cassandra D. Ragnauth et al.   CIRCULATION

Cellular senescence: putting the paradoxes in perspective

(2010) Judith Campisi   CURRENT OPINION IN GENETICS & DEVELOPMENT

Assembly and function of DNA double-strand break repair foci in mammalian cells

(2010) Simon Bekker-Jensen et al.   DNA REPAIR

Cancer Risks After Radiation Exposure in Middle Age

(2010) I. Shuryak et al.   JNCI-Journal of the National Cancer Institute

Intrinsic radiosensitivity correlated with radiation-induced ROS and cell cycle regulation

(2010) Ki Moon Seong et al.   Molecular & Cellular Toxicology

A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation

(2010) Michael Hinz et al.   MOLECULAR CELL

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Altered Chromosomal Positioning, Compaction, and Gene Expression with a Lamin A/C Gene Mutation

(2010) Stephanie K. Mewborn et al.   PLoS One

Delayed kinetics of DNA double-strand break processing in normal and pathological aging

(2009) Olga A. Sedelnikova et al.   AGING CELL

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

Antioxidant status in breast cancer patients of different ages after radiotherapy

(2009) Jelena Kasapovic et al.   Archives of Biological Sciences

Is the oxidative stress theory of aging dead?

(2009) Viviana I. Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells

(2009) Maximiliano A. D'Angelo et al.   CELL

When a theory of aging ages badly

(2009) Jérôme Lapointe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nuclear pore complex biogenesis

(2009) Javier Fernandez-Martinez et al.   CURRENT OPINION IN CELL BIOLOGY

Novel roles for A-type lamins in telomere biology and the DNA damage response pathway

(2009) Ignacio Gonzalez-Suarez et al.   EMBO JOURNAL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Exposure to Low-Dose Ionizing Radiation from Medical Imaging Procedures

(2009) Reza Fazel et al.   NEW ENGLAND JOURNAL OF MEDICINE

The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms

(2008) Rochelle Buffenstein et al.   AGE

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY