HIT'nDRIVE: patient-specific multidriver gene prioritization for precision oncology
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Title
HIT'nDRIVE: patient-specific multidriver gene prioritization for precision oncology
Authors
Keywords
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Journal
GENOME RESEARCH
Volume 27, Issue 9, Pages 1573-1588
Publisher
Cold Spring Harbor Laboratory
Online
2017-07-19
DOI
10.1101/gr.221218.117
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Note: Only part of the references are listed.- A Landscape of Pharmacogenomic Interactions in Cancer
- (2016) Francesco Iorio et al. CELL
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- Perspective: The precision-oncology illusion
- (2016) Vinay Prasad NATURE
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
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- (2016) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
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- (2016) A Gupta et al. ONCOGENE
- MADGiC: a model-based approach for identifying driver genes in cancer
- (2015) Keegan D. Korthauer et al. BIOINFORMATICS
- Integration of somatic mutation, expression and functional data reveals potential driver genes predictive of breast cancer survival
- (2015) Chen Suo et al. BIOINFORMATICS
- The Molecular Taxonomy of Primary Prostate Cancer
- (2015) Adam Abeshouse et al. CELL
- Whole–genome characterization of chemoresistant ovarian cancer
- (2015) Ann-Marie Patch et al. NATURE
- Systematic analysis of somatic mutations impacting gene expression in 12 tumour types
- (2015) Jiarui Ding et al. Nature Communications
- Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response
- (2015) Himisha Beltran et al. JAMA Oncology
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- (2014) F. Lin et al. CLINICAL CANCER RESEARCH
- Activity of trametinib in K601E and L597Q BRAF mutation-positive metastatic melanoma
- (2014) Samantha E. Bowyer et al. MELANOMA RESEARCH
- Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
- (2014) Eliezer M Van Allen et al. NATURE MEDICINE
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE)
- (2013) Evan O. Paull et al. BIOINFORMATICS
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Emerging landscape of oncogenic signatures across human cancers
- (2013) Giovanni Ciriello et al. NATURE GENETICS
- DGIdb: mining the druggable genome
- (2013) Malachi Griffith et al. NATURE METHODS
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Identifying potential cancer driver genes by genomic data integration
- (2013) Yong Chen et al. Scientific Reports
- Simultaneous Identification of Multiple Driver Pathways in Cancer
- (2013) Mark D. M. Leiserson et al. PLoS Computational Biology
- DriverNet: uncovering the impact of somatic driver mutations on transcriptional networks in cancer
- (2013) Ali Bashashati et al. GENOME BIOLOGY
- A network-based, integrative study to identify core biological pathways that drive breast cancer clinical subtypes
- (2012) B Dutta et al. BRITISH JOURNAL OF CANCER
- Clonal evolution in cancer
- (2012) Mel Greaves et al. NATURE
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- The mutational landscape of lethal castration-resistant prostate cancer
- (2012) Catherine S. Grasso et al. NATURE
- The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
- (2012) Christina Curtis et al. NATURE
- Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
- (2012) Li Ding et al. NATURE
- Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
- (2012) Christopher E Barbieri et al. NATURE GENETICS
- BRAF L597 Mutations in Melanoma Are Associated with Sensitivity to MEK Inhibitors
- (2012) Kimberly Brown Dahlman et al. Cancer Discovery
- Optimally discriminative subnetwork markers predict response to chemotherapy
- (2011) P. Dao et al. BIOINFORMATICS
- Correlation of Somatic Mutation and Expression Identifies Genes Important in Human Glioblastoma Progression and Survival
- (2011) D. L. Masica et al. CANCER RESEARCH
- Mutual exclusivity analysis identifies oncogenic network modules
- (2011) G. Ciriello et al. GENOME RESEARCH
- Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
- (2011) Brian D. Lehmann et al. JOURNAL OF CLINICAL INVESTIGATION
- Algorithms for Detecting Significantly Mutated Pathways in Cancer
- (2011) Fabio Vandin et al. JOURNAL OF COMPUTATIONAL BIOLOGY
- Network modeling of the transcriptional effects of copy number aberrations in glioblastoma
- (2011) R. Jornsten et al. Molecular Systems Biology
- Integrated genomic analyses of ovarian carcinoma
- (2011) D. Bell et al. NATURE
- ResponseNet: revealing signaling and regulatory networks linking genetic and transcriptomic screening data
- (2011) A. Lan et al. NUCLEIC ACIDS RESEARCH
- Identifying Causal Genes and Dysregulated Pathways in Complex Diseases
- (2011) Yoo-Ah Kim et al. PLoS Computational Biology
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- (2010) Ahrim Youn et al. BIOINFORMATICS
- Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM
- (2010) Charles J. Vaske et al. BIOINFORMATICS
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- (2010) Roel G.W. Verhaak et al. CANCER CELL
- An Integrated Approach to Uncover Drivers of Cancer
- (2010) Uri David Akavia et al. CELL
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- (2009) Michael R. Stratton et al. NATURE
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- (2009) Esti Yeger-Lotem et al. NATURE GENETICS
- eQED: an efficient method for interpreting eQTL associations using protein networks
- (2008) Silpa Suthram et al. Molecular Systems Biology
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- (2008) Roger McLendon et al. NATURE
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
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