Identifying Causal Genes and Dysregulated Pathways in Complex Diseases

PI3K/PTEN/Akt pathway status affects the sensitivity of high-grade glioma cell cultures to the insulin-like growth factor-1 receptor inhibitor NVP-AEW541

(2010) Daniel Hägerstrand et al.   NEURO-ONCOLOGY

A novel algorithm for detecting differentially regulated paths based on gene set enrichment analysis

(2009) Andreas Keller et al.   BIOINFORMATICS

Unsupervised Analysis of Transcriptomic Profiles Reveals Six Glioma Subtypes

(2009) A. Li et al.   CANCER RESEARCH

Molecular networks as sensors and drivers of common human diseases

(2009) Eric E. Schadt   NATURE

Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

(2009) Esti Yeger-Lotem et al.   NATURE GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets

(2009) Elizabeth Iorns et al.   PLoS One

Information Flow Analysis of Interactome Networks

(2009) Patrycja Vasilyev Missiuro et al.   PLoS Computational Biology

Walking the Interactome for Prioritization of Candidate Disease Genes

(2008) Sebastian Köhler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

eQED: an efficient method for interpreting eQTL associations using protein networks

(2008) Silpa Suthram et al.   Molecular Systems Biology

Reactome knowledgebase of human biological pathways and processes

(2008) L. Matthews et al.   NUCLEIC ACIDS RESEARCH

Identification of candidate prostate cancer genes through comparative expression‐profiling of seminal vesicle

(2008) Maxwell Thompson et al.   PROSTATE

Inferring Pathway Activity toward Precise Disease Classification

(2008) Eunjung Lee et al.   PLoS Computational Biology

Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality

(2008) Elena Zotenko et al.   PLoS Computational Biology