Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair

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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

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Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks

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Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems

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Two Distinct Pathways Support Gene Correction by Single-Stranded Donors at DNA Nicks

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Development and Applications of CRISPR-Cas9 for Genome Engineering

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A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression

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Fine-Tuning of DNA Damage-Dependent Ubiquitination by OTUB2 Supports the DNA Repair Pathway Choice

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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

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Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

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Variants of a Thermus aquaticus DNA Polymerase with Increased Selectivity for Applications in Allele- and Methylation-Specific Amplification

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The new frontier of genome engineering with CRISPR-Cas9

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Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?

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Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

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R Loops: From Transcription Byproducts to Threats to Genome Stability

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Rad52 inactivation is synthetically lethal with BRCA2 deficiency

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Competition between the RNA Transcript and the Nontemplate DNA Strand during R-Loop Formation In Vitro: a Nick Can Serve as a Strong R-Loop Initiation Site

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