Methods for meta-analysis of multiple traits using GWAS summary statistics

A novel association test for multiple secondary phenotypes from a case-control GWAS

(2017) Debashree Ray et al.   GENETIC EPIDEMIOLOGY

Multivariate simulation framework reveals performance of multi-trait GWAS methods

(2017) Heather F. Porter et al.   Scientific Reports

On Sample Size and Power Calculation for Variant Set-Based Association Tests

(2016) Baolin Wu et al.   ANNALS OF HUMAN GENETICS

metaCCA: summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

(2016) Anna Cichonska et al.   BIOINFORMATICS

The genetic architecture of type 2 diabetes

(2016) Christian Fuchsberger et al.   NATURE

Unravelling the human genome–phenome relationship using phenome-wide association studies

(2016) William S. Bush et al.   NATURE REVIEWS GENETICS

Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases

(2016) Liang He et al.   Frontiers in Genetics

Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension

(2015) Xiaofeng Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An Adaptive Association Test for Multiple Phenotypes with GWAS Summary Statistics

(2015) Junghi Kim et al.   GENETIC EPIDEMIOLOGY

USAT: A Unified Score-Based Association Test for Multiple Phenotype-Genotype Analysis

(2015) Debashree Ray et al.   GENETIC EPIDEMIOLOGY

Semiparametric Allelic Tests for Mapping Multiple Phenotypes: Binomial Regression and Mahalanobis Distance

(2015) Arunabha Majumdar et al.   GENETIC EPIDEMIOLOGY

A Bayesian Partitioning Model for the Detection of Multilocus Effects in Case-Control Studies

(2015) Debashree Ray et al.   HUMAN HEREDITY

The impact of low-frequency and rare variants on lipid levels

(2015) Ida Surakka et al.   NATURE GENETICS

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

A Multi-Trait, Meta-analysis for Detecting Pleiotropic Polymorphisms for Stature, Fatness and Reproduction in Beef Cattle

(2014) Sunduimijid Bolormaa et al.   PLoS Genetics

A Rapid Gene-Based Genome-Wide Association Test with Multivariate Traits

(2013) Saonli Basu et al.   HUMAN HEREDITY

The challenges, advantages and future of phenome-wide association studies

(2013) Scott J. Hebbring   IMMUNOLOGY

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

A Unified Framework for Association Analysis with Multiple Related Phenotypes

(2013) Matthew Stephens   PLoS One

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

(2012) Johannes Kettunen et al.   NATURE GENETICS

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

(2011) Michael C. Wu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

Meta-Analysis of Genome-wide Association Studies with Overlapping Subjects

(2009) Dan-Yu Lin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men

(2009) A. Stancakova et al.   DIABETES

Asymptotic tests of association with multiple SNPs in linkage disequilibrium

(2009) Wei Pan   GENETIC EPIDEMIOLOGY

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

(2009) Sekar Kathiresan et al.   NATURE GENETICS

A multivariate test of association

(2008) Manuel A. R. Ferreira et al.   BIOINFORMATICS

A new chi-square approximation to the distribution of non-negative definite quadratic forms in non-central normal variables

(2008) Huan Liu et al.   COMPUTATIONAL STATISTICS & DATA ANALYSIS