BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method

Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity

(2016) Menglong Zeng et al.   CELL

Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons

(2016) F. Yi et al.   SCIENCE

Glutamate Synapses in Human Cognitive Disorders

(2015) Lenora Volk et al.   Annual Review of Neuroscience

Cdk5 is a New Rapid Synaptic Homeostasis Regulator Capable of Initiating the Early Alzheimer-Like Pathology

(2015) Yanghui Sheng et al.   CEREBRAL CORTEX

CaV3.2 calcium channels control NMDA receptor-mediated transmission: a new mechanism for absence epilepsy

(2015) Guangfu Wang et al.   GENES & DEVELOPMENT

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

(2015) Sang-Won Min et al.   NATURE MEDICINE

The schizophrenia risk gene product miR-137 alters presynaptic plasticity

(2015) Sandra Siegert et al.   NATURE NEUROSCIENCE

An optogenetics- and imaging-assisted simultaneous multiple patch-clamp recording system for decoding complex neural circuits

(2015) Guangfu Wang et al.   Nature Protocols

Rapid Dispersion of SynGAP from Synaptic Spines Triggers AMPA Receptor Insertion and Spine Enlargement during LTP

(2015) Yoichi Araki et al.   NEURON

Biochemical Computation for Spine Structural Plasticity

(2015) Jun Nishiyama et al.   NEURON

Invited review: Frontotemporal dementia caused bymicrotubule-associated protein taugene (MAPT) mutations: a chameleon for neuropathology and neuroimaging

(2015) Bernardino Ghetti et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Behavioral Profile in RASopathies

(2014) Paolo Alfieri et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Pharmacological rescue of Ras signaling, GluA1-dependent synaptic plasticity, and learning deficits in a fragile X model

(2014) C.-S. Lim et al.   GENES & DEVELOPMENT

Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons

(2014) Emily Cunningham Williams et al.   HUMAN MOLECULAR GENETICS

Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome

(2014) Yong-Seok Lee et al.   NATURE NEUROSCIENCE

Targeting RAS–ERK signalling in cancer: promises and challenges

(2014) Ahmed A. Samatar et al.   NATURE REVIEWS DRUG DISCOVERY

Neuregulin-ERBB Signaling in the Nervous System and Neuropsychiatric Diseases

(2014) Lin Mei et al.   NEURON

Reduced Cognition in Syngap1 Mutants Is Caused by Isolated Damage within Developing Forebrain Excitatory Neurons

(2014) Emin D. Ozkan et al.   NEURON

The RASopathies

(2013) Katherine A. Rauen   Annual Review of Genomics and Human Genetics

PTEN signaling in autism spectrum disorders

(2012) Jing Zhou et al.   CURRENT OPINION IN NEUROBIOLOGY

Emerging major synaptic signaling pathways involved in intellectual disability

(2011) A Pavlowsky et al.   MOLECULAR PSYCHIATRY

Induction of human neuronal cells by defined transcription factors

(2011) Zhiping P. Pang et al.   NATURE

Effects of germline mutations in the Ras/MAPK signaling pathway on adaptive behavior: Cardiofaciocutaneous syndrome and Noonan syndrome

(2010) Elizabeth I. Pierpont et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization

(2010) Zheng Li et al.   CELL

Cardio-Facio-Cutaneous Syndrome: Phenotypic Variability and Differential Diagnosis in 3 Cases withde novoBRAF Mutations

(2010) E. Demir et al.   NEUROPEDIATRICS

Ras and Rap Signaling in Synaptic Plasticity and Mental Disorders

(2010) Ruth L. Stornetta et al.   NEUROSCIENTIST

AMPA receptors are exocytosed in stimulated spines and adjacent dendrites in a Ras-ERK-dependent manner during long-term potentiation

(2010) M. A. Patterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN hamartoma tumor syndrome: An overview

(2009) Judith A Hobert et al.   GENETICS IN MEDICINE

Activation of CaMKII in single dendritic spines during long-term potentiation

(2009) Seok-Jin R. Lee et al.   NATURE

Activity Patterns Govern Synapse-Specific AMPA Receptor Trafficking between Deliverable and Synaptic Pools

(2009) Anders Kielland et al.   NEURON

Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7

(2008) Narendra Wajapeyee et al.   CELL

The RAS/MAPK syndromes: novel roles of the RAS pathway in human genetic disorders

(2008) Yoko Aoki et al.   HUMAN MUTATION