Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock

SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression

(2017) Kaixiang Cao et al.   GENES & DEVELOPMENT

Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation

(2017) Sharmistha Kundu et al.   MOLECULAR CELL

Integration of Shh and Fgf signaling in controllingHoxgene expression in cultured limb cells

(2017) Alan R. Rodrigues et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Causal role for inheritance of H3K27me3 in maintaining the OFF state of a Drosophila HOX gene

(2017) Rory T. Coleman et al.   SCIENCE

Species-specific contribution of volumetric growth and tissue convergence to posterior body elongation in vertebrates

(2016) Ben Steventon et al.   DEVELOPMENT

Oct4 Is a Key Regulator of Vertebrate Trunk Length Diversity

(2016) Rita Aires et al.   DEVELOPMENTAL CELL

Polarized regulatory landscape and Wnt responsiveness underlie Hox activation in embryos

(2016) Roel Neijts et al.   GENES & DEVELOPMENT

A role for HOX13 proteins in the regulatory switch between TADs at theHoxDlocus

(2016) Leonardo Beccari et al.   GENES & DEVELOPMENT

CTCF-mediated topological boundaries during development foster appropriate gene regulation

(2016) Varun Narendra et al.   GENES & DEVELOPMENT

A single three-dimensional chromatin compartment in amphioxus indicates a stepwise evolution of vertebrate Hox bimodal regulation

(2016) Rafael D Acemel et al.   NATURE GENETICS

Control ofHoxdgene transcription in the mammary bud by hijacking a preexisting regulatory landscape

(2016) Ruben Schep et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distal Limb Patterning Requires Modulation of cis -Regulatory Activities by HOX13

(2016) Rushikesh Sheth et al.   Cell Reports

Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche

(2016) Shilu Amin et al.   Cell Reports

Position-dependent plasticity of distinct progenitor types in the primitive streak

(2016) Filip J Wymeersch et al.   eLife

The open for business model of the bithorax complex in Drosophila

(2015) Robert K. Maeda et al.   CHROMOSOMA

The significance of Hox gene collinearity

(2015) Stephen J. Gaunt   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Nanoscale spatial organization of theHoxDgene cluster in distinct transcriptional states

(2015) Pierre J. Fabre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTCF establishes discrete functional chromatin domains at theHoxclusters during differentiation

(2015) Varun Narendra et al.   SCIENCE

A time space translation hypothesis for vertebrate axial patterning

(2015) A.J. Durston et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Role ofHoxgenes in stem cell differentiation

(2015) Anne Seifert   World Journal of Stem Cells

Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci

(2014) N. Lonfat et al.   SCIENCE

Conservation and Divergence of Regulatory Strategies at Hox Loci and the Origin of Tetrapod Digits

(2014) Joost M. Woltering et al.   PLOS BIOLOGY

H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex

(2014) Sarah K Bowman et al.   eLife

Direct activation of a mouse Hoxd11 axial expression enhancer by Gdf11/Smad signalling

(2013) Stephen J. Gaunt et al.   DEVELOPMENTAL BIOLOGY

Switching Axial Progenitors from Producing Trunk to Tail Tissues in Vertebrate Embryos

(2013) Arnon Dias Jurberg et al.   DEVELOPMENTAL CELL

Region-specific regulation of posterior axial elongation during vertebrate embryogenesis

(2013) Roel Neijts et al.   DEVELOPMENTAL DYNAMICS

Saltatory remodeling of Hox chromatin in response to rostrocaudal patterning signals

(2013) Esteban O Mazzoni et al.   NATURE NEUROSCIENCE

A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs

(2013) G. Andrey et al.   SCIENCE

Multiple Enhancers Regulate Hoxd Genes and the Hotdog LncRNA during Cecum Budding

(2013) Saskia Delpretti et al.   Cell Reports

Clustering of Tissue-Specific Sub-TADs Accompanies the Regulation of HoxA Genes in Developing Limbs

(2013) Soizik Berlivet et al.   PLoS Genetics

Time Space Translation: A Hox Mechanism for Vertebrate A-P Patterning

(2012) A. J. Durston et al.   CURRENT GENOMICS

Evolutionarily conserved requirement of Cdx for post-occipital tissue emergence

(2012) C. van Rooijen et al.   DEVELOPMENT

The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression

(2012) R. Osorno et al.   DEVELOPMENT

Chromatin loop formation in the β-globin locus and its role in globin gene transcription

(2012) AeRi Kim et al.   MOLECULES AND CELLS

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Spatial partitioning of the regulatory landscape of the X-inactivation centre

(2012) Elphège P. Nora et al.   NATURE

A Regulatory Archipelago Controls Hox Genes Transcription in Digits

(2011) Thomas Montavon et al.   CELL

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

The Dynamic Architecture of Hox Gene Clusters

(2011) D. Noordermeer et al.   SCIENCE

The Origin of Digits: Expression Patterns versus Regulatory Mechanisms

(2010) Joost M. Woltering et al.   DEVELOPMENTAL CELL

Stem cells, signals and vertebrate body axis extension

(2009) V. Wilson et al.   DEVELOPMENT

Redefining the Progression of Lineage Segregations during Mammalian Embryogenesis by Clonal Analysis

(2009) Elena Tzouanacou et al.   DEVELOPMENTAL CELL

Cdx and Hox Genes Differentially Regulate Posterior Axial Growth in Mammalian Embryos

(2009) Teddy Young et al.   DEVELOPMENTAL CELL

Developmental control of segment numbers in vertebrates

(2009) Céline Gomez et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

Epigenetic Temporal Control of Mouse Hox Genes in Vivo

(2009) N. Soshnikova et al.   SCIENCE

Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity

(2008) M. J. McGrew et al.   DEVELOPMENT

Regulation of Canonical Wnt Signaling by Brachyury Is Essential for Posterior Mesoderm Formation

(2008) Benjamin L. Martin et al.   DEVELOPMENTAL CELL

MicroRNAs in the Hox network: an apparent link to posterior prevalence

(2008) Soraya Yekta et al.   NATURE REVIEWS GENETICS