Article
Engineering, Marine
Po-Tsang Lee, Yu-Sheng Wu, Chung-Chih Tseng, Jia-Yu Lu, Meng-Chou Lee
Summary: This study evaluated the effects of feeding Nile tilapia with spent mushroom substrate from Agaricus blazei. The results showed that the substrate enhanced the immune activity of the fish and protected them against Streptococcus agalactiae infection. This study provides a new direction for the development of more effective feed additives.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Gen Zou, Bo Li, Ying Wang, Xin Yin, Ming Gong, Junjun Shang, Yongjun Wei, Xiaoling Li, Dapeng Bao
Summary: Engineered Cordyceps militaris can convert spent mushroom substrate (SMS) into the anticancer drug pentostatin, utilizing lignocellulosic waste for high-value product biosynthesis. Featuring strong hydrolytic activity towards cellulose and increased pentostatin production, this biological strategy offers a sustainable solution for SMS pollution removal while producing valuable bioactive compounds.
Article
Fisheries
Nguyen Vu Linh, Le Thanh Dien, Wattana Panphut, Anat Thapinta, Saengchan Senapin, Sophie St-Hilaire, Channarong Rodkhum, Ha Thanh Dong
Summary: The study showed that ozone nanobubble (NB-O3) can activate the innate immunity genes of Nile tilapia, improving their resistance to bacterial infections and increasing survival rates.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Immunology
Qi Li, Zhiqiang Zhang, Weiqi Fan, Yongxiong Huang, Jinzhong Niu, Guoling Luo, Xinchao Liu, Yu Huang, Jichang Jian
Summary: The study identified a lect2 gene from Nile tilapia (On-lect2) and characterized its roles in the fish's immune response against bacterial infection. On-LECT2 plays important functions in promoting inflammation, reducing tissue damages, and improving survival rate of Nile tilapia during bacterial infection, with the highest transcriptional levels in the liver.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Fisheries
Yanjian Yang, Meng Chen, Zhelin Wu, Defeng Zhang, Huiyan Lin, Xiayi Wei, Biao Han, Zheng Guo, Jianmin Ye
Summary: This study found that the phagocytosis of Streptococcus agalactiae by tilapia macrophages was significantly enhanced in cps-deficient mutant Delta cps and sia-deficient mutant Delta neuA. By dampening the inflammatory response and down-regulating the expression of phagocytic receptors, S. agalactiae could interfere with the phagocytosis of macrophages. These findings provide valuable insights into the defense mechanisms of S. agalactiae against the teleost innate immune system and offer clues for vaccine development.
Article
Fisheries
Tao Zhou, Zhihua Fang, Daniel F. C. Duarte, Stefan A. Fernandes, Ying Lu, Jing Guo, Lang Gui, Liangbiao Chen
Summary: This study investigated the mechanisms of gill damage in tilapia infected with Streptococcus agalactiae. Transcriptomic analysis revealed differentially expressed genes and enriched immune-related gene ontology and pathways. HE staining results showed severe gill damage in tilapia at 9 hours post-infection.
Article
Multidisciplinary Sciences
Danyu Zhang, Qingjiu Tang, Xianzhe He, Yipeng Wang, Guangyong Zhu, Ling Yu
Summary: This study determined the antioxidant, anti-inflammatory, and inhibitory activities of the extract from the spent substrate of Cordyceps militaris. The extract showed potential as a safe and efficacious source for pharmaceutical or cosmetic applications with its ability to inhibit Malassezia, scavenge free radicals, and protect cells from oxidative damage.
Article
Immunology
Qi Li, Baijian Jiang, Zhiqiang Zhang, Yongxiong Huang, Zhou Xu, Xinjin Chen, Xitan Hou, Jia Cai, Yu Huang, Jichang Jian
Summary: This study identified and characterized various serotonergic markers in Nile tilapia and investigated the involvement of the serotonin system during bacterial infection. The results showed that serotonergic marker genes were mainly expressed in the brain, and their expression was induced during infection. However, few serotonergic markers were found in immune cells, and no significant immunomodulation effect was observed during the immune response.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Fisheries
Qi Li, Baijian Jiang, Zhiqiang Zhang, Yongxiong Huang, Zhou Xu, Xinjin Chen, Yu Huang, Jichang Jian
Summary: Substance P plays a crucial role in the immune response to acute bacterial infection in fish, promoting pyroptosis, suppressing inflammation, and improving survival rate.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Huiling Hu, Zhiwen Wang, Dapeng Yu, Liqun Xia, Wenjie Chen, Meng Long, Huimin Fan, Hongli Xia, Yishan Lu
Summary: TRAF2 plays a dual role in immune signaling transduction processes. In this study, OnTRAF2 was cloned from Nile tilapia and found to be widely expressed in healthy tilapia, with highest expression level in the brain. After Streptococcus agalactiae infection, the expression level of OnTRAF2 significantly increased, indicating its involvement in host defense against the infection.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Biology
Qi Li, Baijian Jiang, Zhiqiang Zhang, Yongxiong Huang, Zhou Xu, Xinjin Chen, Jia Cai, Yu Huang, Jichang Jian
Summary: This study identified a CRP gene from Nile tilapia and investigated its roles in bacterial infection. The results revealed that CRP participates in the anti-bacterial immune response through bacterial agglutination, phagocytosis regulation, and inflammation. This research provides a theoretical foundation for further exploring the protective mechanism of fish CRP against bacterial infection.
Article
Fisheries
Huiling Hu, Hongli Xia, Luxi Xu, Zhiwen Wang, Yishan Lu, Jichang Jian
Summary: This study explores the role of CD36 in the antimicrobial immunity of Nile tilapia. The results show that CD36 is conserved among species and is distributed in the cell membrane. CD36 gene is expressed in all tissues of healthy tilapia, with higher expression in immune tissues. Overexpression of CD36 reduces bacterial load and protects immune tissues from injury, and it also decreases pro-inflammatory factors and increases anti-inflammatory factors. CD36 may play a vital role in pathogen control and immune response in tilapia.
Article
Fisheries
Qi Li, Baijian Jiang, Zhiqiang Zhang, Yongxiong Huang, Zhou Xu, Xinjin Chen, Yu Huang, Jichang Jian, Qingpi Yan
Summary: This study characterizes the expression and functions of alpha-MSH in Nile tilapia. It was found that alpha-MSH is mainly expressed in the brain, skin, and liver, and is upregulated after Streptococcus agalactiae infection. However, its expression in immune organs or lymphocytes is minimal and has no significant immunomodulation effect in vitro. In vivo challenge experiments showed that alpha-MSH protects tilapia from bacterial infection by regulating responses in the brain and intestine.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Hongli Xia, Huiling Hu, Zhiwen Wang, Liqun Xia, Wenjie Chen, Meng Long, Zhen Gan, Huimin Fan, Dapeng Yu, Yishan Lu
Summary: In this study, a NEDD4 gene (OnNEDD4) was identified and analyzed in Nile tilapia. OnNEDD4 was found to be constitutively expressed in all examined tissues, with the highest expression level in thymus. After Streptococcus agalactiae stimulation, the expression of OnNEDD4 was significantly induced in several tissues. Moreover, OnNEDD4 was found to interact with the extracellular region of OnCD40.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Environmental Sciences
Wangkheimayum Malemnganbi Devi, Himadri Saha, Surajkumar Irungbam, Ratan Kumar Saha
Summary: The study investigated the use of Cordyceps militaris spent mushroom substrate (CMSMS) as an alternative to in-feed antibiotics for fish. The results showed that a dose of 30g/kg of CMSMS had a better immune response and improved survival rate in Labeo rohita fish. This suggests that CMSMS can be safely used as an in-feed antibiotic in fish and can reduce concerns related to by-product disposal from mushroom cultivation.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Fisheries
Ghasem Mohammadi, Mahmoud Hafezieh, Ali Akbar Karimi, Mohamad Nor Azra, Hien Van Doan, Wanaporn Tapingkae, Hisham A. Abdelrahman, Mahmoud A. O. Dawood
Summary: This study evaluated the effects of pistachio hulls derived polysaccharide (PHDP) and Pediococcus acidilactici (PA) separately or as a synbiotic on the growth performance, immune responses, and disease resistance of Nile tilapia. The results showed significantly improved growth performance, immune responses, and disease resistance in fish fed with the synbiotic feed additive compared to the control group.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Malik M. Khalafalla, Nahed F. A. Zayed, Asem A. Amer, Ali A. Soliman, Amr Zaineldin, Mahmoud S. Gewaily, Aziza M. Hassan, Hien Van Doan, Wanaporn Tapingkae, Mahmoud A. O. Dawood
Summary: Dietary supplementation of Lactobacillus acidophilus ATCC 4356 can effectively alleviate the negative impacts of aflatoxin B-1 on the growth performance and blood parameters of Liza ramada. It improves growth performance, increases red blood cell and hemoglobin levels, enhances blood protein content, reduces cholesterol and triglyceride levels, and mitigates liver function abnormalities caused by aflatoxin B-1. Additionally, Lactobacillus acidophilus ATCC 4356 can alleviate intestinal and liver damage induced by aflatoxin B-1.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2022)
Article
Agriculture, Dairy & Animal Science
Chanidapha Kanmanee, Orranee Srinual, Montri Punyatong, Tossapol Moonmanee, Chompunut Lumsangkul, Suchon Tangtaweewipat, Hien Van Doan, Mongkol Yachai, Thanongsak Chaiyaso, Wanaporn Tapingkae
Summary: The present study investigated the effect of red yeast supplementation as a substitute for antibiotics in the diet of laying hens. The results show that supplementation with red yeast has a positive effect on growth performance, egg quality, and small intestinal health. Specifically, supplementation with 2.0 g/kg of red yeast can replace the use of antibiotics in layer diets.
Article
Agriculture, Dairy & Animal Science
Punnawut Yama, Chayanon Yadmak, Molarat Sangkate, Jakree Jitjumnong, Warittha U-krit, Nalinthip Promsao, Napatsorn Montha, Paiwan Sudwan, Raktham Mektrirat, Julakorn Panatuk, Wilasinee Inyawilert, Korawan Sringarm, Chompunut Lumsangkul, Wanaporn Tapingkae, Hien Van Doan, Pin-Chi Tang, Tossapol Moonmanee
Summary: The study showed that follicular and uterine arterial indices from color Doppler ultrasonography could be helpful in predicting the resumption of ovarian activity after hormonal stimulation in inactive ovary cows, providing important clinical implications.
Article
Fisheries
Fawzy Magouz, Hasnaa Abu-Ghanima, Amr Zaineldin, Mahmoud S. Gewaily, Ali Soliman, Asem A. Amer, Eman M. Moustafa, Elsayed M. Younis, Abdel-Wahab A. Abdel-Warith, Simon J. Davies, Hien Van Doan, Wanaporn Tapingkae, Mahmoud A. O. Dawood
Summary: In this study, it was found that Bacillus subtilis can alleviate the negative effects of mycotoxins on Mullet performance, while ochratoxin A reduces performance. Additionally, dietary supplementation of Bacillus subtilis can improve fish growth, immune system function, and reduce pathological effects, while ochratoxin A has adverse effects on fish health.
AQUACULTURE REPORTS
(2022)
Article
Microbiology
Wanaporn Tapingkae, Orranee Srinual, Chompunut Lumsangkul, Hien Van Doan, Hsin- Chiang, Atchara Manowattana, Pinpanit Boonchuay, Thanongsak Chaiyaso
Summary: Red yeast cells (RYCs) have been recognized as a potential feed additive due to their nutritional value and ability to bind mycotoxins. This study demonstrated the industrial feasibility of large-scale production of RYCs and tested their mycotoxin binding capacity.
Article
Biotechnology & Applied Microbiology
Tanyawat Kaewsalud, Kamon Yakul, Chayatip Insomphun, Kittisak Jantanasakulwong, Pornchai Rachtanapun, Wanaporn Tapingkae, Santi Chuetor, Masanori Watanabe, Thanongsak Chaiyaso
Summary: In this study, Thermoactinomyces vulgaris TK1-21 exhibited a good ability to degrade keratin wastes from chicken feathers, pig bristles, and pig hooves. The produced keratinases efficiently hydrolyzed the hydrothermally treated waste materials into keratin hydrolysate with high soluble protein concentrations and antioxidant activities. The incorporation of these hydrolysates into bioplastics improved their tensile strength and elongation at break.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2023)
Article
Fisheries
Milad Maniat, Amir Parviz Salati, Nasim Zanguee, Seyed Mohammad Mousavi, Seyed Hossein Hoseinifar
Summary: The study aimed to examine the synbiotic effects of Pediococcus acidilactici (PA) and isomaltooligosaccharide (IMO) on the growth and immunity of juvenile common carp. The results showed that the diet supplemented with 1 g/kg PA and 5 g/kg IMO significantly improved the growth performance and immune responses of the fish. Therefore, the combination of PA and IMO can be recommended as a beneficial synbiotic additive and immunostimulant in juvenile common carp.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Hamed Ghafarifarsani, Shiva Nedaei, Seyed Hossein Hoseinifar, Hien Van Doan
Summary: This study investigates the effects of chlorogenic acid (ChA) in the diet on the growth performance, digestive enzyme activity, immunological variables, and disease resistance of rainbow trout juveniles. The findings show that the group receiving 600 mg kg(-1) ChA-supplemented diet demonstrates the lowest feed conversion ratio and highest specific growth rate. The results suggest that ChA can improve the growth parameters, immune indices, antioxidant capacity, and disease resistance in rainbow trout.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Hamed Ghafarifarsani, Seyed Hossein Hoseinifar, Taravat Molayemraftar, Mahdieh Raeeszadeh, Hien Van Doan
Summary: The study found that adding pot marigold powder at 1%, 1.5%, and 2% levels to the diet of rainbow trout significantly improved growth, immune response, and disease resistance. In addition, the 1% and 1.5% MP groups showed increased digestive enzyme activities and antioxidant capacity. The highest survival rate after Yersinia ruckeri infection was observed in the 1.5% MP group compared to the control group.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Kobra Armobin, Ehsan Ahmadifar, Hossein Adineh, Mahsa Naderi Samani, Naser Kalhor, Sevdan Yilmaz, Seyed Hossein Hoseinifar, Hien Van Doan
Summary: This study aimed to evaluate the effects of different levels of quercetin on the growth performance, immune responses, antioxidant status, serum biochemical factors, and high-temperature stress responses in common carp. The results showed that feeding diets supplemented with 400-600 mg/kg quercetin improved growth performance, immunity, and antioxidant status, and increased tolerance to heat stress in common carp.
AQUACULTURE NUTRITION
(2023)
Review
Agriculture, Dairy & Animal Science
Seyed Hossein Hoseinifar, Francesca Maradonna, Mehwish Faheem, Ramasamy Harikrishnan, Gunapathy Devi, Einar Ringo, Hien Van Doan, Ghasem Ashouri, Giorgia Gioacchini, Oliana Carnevali
Summary: Ornamental fish husbandry faces challenges and losses, such as transport stress and disease outbreaks. This review discusses measures to prevent or control fish diseases and the role of natural and sustainable microbial feed additives (such as probiotics, prebiotics, and synbiotics) in enhancing the health, reducing transport stress, and promoting growth and reproduction of farmed ornamental fish. The review aims to fill the knowledge gap in advanced and sustainable practices in ornamental fish production.
Article
Agriculture, Dairy & Animal Science
Dara Bagheri, Rohullah Moradi, Mahyar Zare, Ebrahim Sotoudeh, Seyed Hossein Hoseinifar, Amin Oujifard, Noah Esmaeili
Summary: This study investigated the effects of low molecular weight sodium alginate (LMWSA) on the growth and health of whiteleg shrimp, as well as its potential in alleviating negative impacts of cadmium. The results showed that LMWSA improved feed conversion ratio and antioxidant parameters, and prevented the suppression of antioxidant system parameters caused by cadmium. The 2.0 LMWSA treatment had the best performance in various parameters, and increasing LMWSA levels gradually is recommended.
Article
Fisheries
Allieh Bairami Igdery, Mohammad Farhangi, Hossein Adineh, Hojatollah Jafaryan, Zia Kordjazi, Seyed Hossein Hoseinifar
Summary: Herbal treatment with ginger powder enhances the immune and antioxidant responses, improves growth, and increases stress resistance in Caspian roach. The inclusion of 10 and 20 g/kg ginger powder in the diet shows the most significant effects on the final weight, specific growth rate, antioxidant enzyme activity, and immune indices. Ginger can be considered as a beneficial supplement for promoting the overall health and survival of this endangered fish species.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Majid Khanzadeh, Babak Beikzadeh, Seyed Hossein Hoseinifar
Summary: This study finds that red macroalgae extract (Laurencia caspica) has positive effects on hematological, immunological, antioxidant, biochemical, and disease resistance of Nile tilapia against S. agalactiae. After 50-day feeding, the white blood cells, hemoglobin, and neutrophils of fish significantly increased. Immunological parameters (including IgM and C3) were also significantly higher in the treated groups. Additionally, the extract intake significantly increased antioxidant enzyme activities and improved survival rates of fish infected with S. agalactiae.
AQUACULTURE NUTRITION
(2023)
