Structural characterization of the linked NS2B-NS3 protease of Zika virus

Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease

(2016) Xia Chen et al.   CELL RESEARCH

First detection of autochthonous Zika virus transmission in a HIV-infected patient in Rio de Janeiro, Brazil

(2016) Guilherme A. Calvet et al.   JOURNAL OF CLINICAL VIROLOGY

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

(2016) Van-Mai Cao-Lormeau et al.   LANCET

Zika Virus Infection in Pregnant Women in Rio de Janeiro

(2016) Patrícia Brasil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain

(2016) A.E. Shannon et al.   PROTEIN EXPRESSION AND PURIFICATION

One year later, Zika scientists prepare for a long war

(2016) G. Vogel   SCIENCE

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

(2016) Jian Lei et al.   SCIENCE

Crystal structure of unlinked NS2B-NS3 protease from Zika virus

(2016) Zhenzhen Zhang et al.   SCIENCE

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

(2016) Wint Wint Phoo et al.   Nature Communications

The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development

(2015) Dahai Luo et al.   ANTIVIRAL RESEARCH

Biochemistry and Medicinal Chemistry of the Dengue Virus Protease

(2014) Christoph Nitsche et al.   CHEMICAL REVIEWS

Binding mode of the activity-modulating C-terminal segment of NS2B to NS3 in the dengue virus NS2B-NS3 protease

(2014) Laura de la Cruz et al.   FEBS Journal

Functional interplay among the flavivirus NS3 protease, helicase, and cofactors

(2014) Kuohan Li et al.   VIROLOGICA SINICA

NMR Analysis of a Novel Enzymatically Active Unlinked Dengue NS2B-NS3 Protease Complex

(2013) Young Mee Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the binding of peptidic West Nile virus NS2B–NS3 protease inhibitors by NMR

(2012) CongBao Kang et al.   ANTIVIRAL RESEARCH

Binding of Low Molecular Weight Inhibitors Promotes Large Conformational Changes in the Dengue Virus NS2B-NS3 Protease: Fold Analysis by Pseudocontact Shifts

(2011) Laura de la Cruz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

(2011) C. G. Noble et al.   JOURNAL OF VIROLOGY

NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease

(2009) Xun-Cheng Su et al.   FEBS Journal

Discovery of a Non-Peptidic Inhibitor of West Nile Virus NS3 Protease by High-Throughput Docking

(2009) Dariusz Ekonomiuk et al.   PLoS Neglected Tropical Diseases

NMR Analysis of the Dynamic Exchange of the NS2B Cofactor between Open and Closed Conformations of the West Nile Virus NS2B-NS3 Protease

(2009) Xun-Cheng Su et al.   PLoS Neglected Tropical Diseases

Structure of West Nile Virus NS3 Protease: Ligand Stabilization of the Catalytic Conformation

(2008) Gautier Robin et al.   JOURNAL OF MOLECULAR BIOLOGY