Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

An introduction to data reduction: space-group determination, scaling and intensity statistics

(2011) Philip R. Evans   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Tripeptide inhibitors of dengue and West Nile virus NS2B–NS3 protease

(2011) Andreas Schüller et al.   ANTIVIRAL RESEARCH

Structure-guided fragment-based in silico drug design of dengue protease inhibitors

(2011) Tim Knehans et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Dengue: a continuing global threat

(2010) Maria G. Guzman et al.   NATURE REVIEWS MICROBIOLOGY

A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease

(2009) Christophe Bodenreider et al.   ANALYTICAL BIOCHEMISTRY

Crystal Structure of a Novel Conformational State of the Flavivirus NS3 Protein: Implications for Polyprotein Processing and Viral Replication

(2009) R. Assenberg et al.   JOURNAL OF VIROLOGY

Serotype-Specific Structural Differences in the Protease-Cofactor Complexes of the Dengue Virus Family

(2009) S. Chandramouli et al.   JOURNAL OF VIROLOGY

NMR Analysis of the Dynamic Exchange of the NS2B Cofactor between Open and Closed Conformations of the West Nile Virus NS2B-NS3 Protease

(2009) Xun-Cheng Su et al.   PLoS Neglected Tropical Diseases

Towards the design of antiviral inhibitors against flaviviruses: The case for the multifunctional NS3 protein from Dengue virus as a target

(2008) J LESCAR et al.   ANTIVIRAL RESEARCH

West Nile Virus NS2B/NS3 Protease As An Antiviral Target

(2008) K. Chappell et al.   CURRENT MEDICINAL CHEMISTRY

Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity

(2008) K. J. Chappell et al.   JOURNAL OF GENERAL VIROLOGY

Structure of West Nile Virus NS3 Protease: Ligand Stabilization of the Catalytic Conformation

(2008) Gautier Robin et al.   JOURNAL OF MOLECULAR BIOLOGY