The Radical SAM enzyme NirJ catalyzes the removal of two propionate side chains during heme d 1 biosynthesis

Elucidation of the biosynthesis of the methane catalyst coenzyme F430

(2017) Simon J. Moore et al.   NATURE

On the Role of Additional [4Fe-4S] Clusters with a Free Coordination Site in Radical-SAM Enzymes

(2017) Etienne Mulliez et al.   Frontiers in Chemistry

The auxiliary [4Fe–4S] cluster of the Radical SAM heme synthase from Methanosarcina barkeri is involved in electron transfer

(2016) Melanie Kühner et al.   Chemical Science

Auxiliary iron–sulfur cofactors in radical SAM enzymes

(2015) Nicholas D. Lanz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The EMBL-EBI bioinformatics web and programmatic tools framework

(2015) Weizhong Li et al.   NUCLEIC ACIDS RESEARCH

Characterisation of Desulfovibrio vulgaris haem b synthase, a radical SAM family member

(2014) Susana A.L. Lobo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Recent advances in the biosynthesis of modified tetrapyrroles: the discovery of an alternative pathway for the formation of heme and heme d 1

(2014) Shilpa Bali et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NirN Protein fromPseudomonas aeruginosais a Novel Electron-bifurcating Dehydrogenase Catalyzing the Last Step of Hemed1Biosynthesis

(2014) Julia Adamczack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SPASM and Twitch Domains inS-Adenosylmethionine (SAM) Radical Enzymes

(2014) Tsehai A. J. Grell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Crystal Structure of Siroheme Decarboxylase in Complex with Iron-Uroporphyrin III Reveals Two Essential Histidine Residues

(2014) Kristin Haufschildt et al.   JOURNAL OF MOLECULAR BIOLOGY

The Alternative Route to Heme in the Methanogenic ArchaeonMethanosarcina barkeri

(2014) Melanie Kühner et al.   ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL

Further Characterization of Cys-Type and Ser-Type Anaerobic Sulfatase Maturating Enzymes Suggests a Commonality in the Mechanism of Catalysis

(2013) Tyler L. Grove et al.   BIOCHEMISTRY

X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry

(2013) P. J. Goldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification

(2013) P. J. Goldman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12)

(2013) S. J. Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spectroscopic, Steady-State Kinetic, and Mechanistic Characterization of the Radical SAM Enzyme QueE, Which Catalyzes a Complex Cyclization Reaction in the Biosynthesis of 7-Deazapurines

(2012) Reid M. McCarty et al.   BIOCHEMISTRY

Identification and function of auxiliary iron–sulfur clusters in radical SAM enzymes

(2012) Nicholas D. Lanz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A

(2012) Leif Flühe et al.   Nature Chemical Biology

Observation of fast release of NO from ferrousd1haem allows formulation of a unified reaction mechanism for cytochromecd1nitrite reductases

(2011) Serena Rinaldo et al.   BIOCHEMICAL JOURNAL

Biological Systems Discovery In Silico: Radical S-Adenosylmethionine Protein Families and Their Target Peptides for Posttranslational Modification

(2011) D. H. Haft et al.   JOURNAL OF BACTERIOLOGY

Crystal Structure of the Hemed1Biosynthesis Enzyme NirE in Complex with Its Substrate Reveals New Insights into the Catalytic Mechanism ofS-Adenosyl-l-methionine-dependent Uroporphyrinogen III Methyltransferases

(2011) Sonja Storbeck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Molecular hijacking of siroheme for the synthesis of heme and d1 heme

(2011) S. Bali et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Consensus Mechanism for Radical SAM-Dependent Dehydrogenation? BtrN Contains Two [4Fe-4S] Clusters

(2010) Tyler L. Grove et al.   BIOCHEMISTRY

NirF is a periplasmic protein that binds d1 heme as part of its essential role in d1 heme biogenesis

(2010) Shilpa Bali et al.   FEBS Journal

NirJ, a radical SAM family member of thed1heme biogenesis cluster

(2010) Amanda A. Brindley et al.   FEBS LETTERS

d1 haem biogenesis - assessing the roles of three nir gene products

(2009) Richard S. Zajicek et al.   FEBS Journal

The Pseudomonas aeruginosa nirE gene encodes the S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase required for heme d1 biosynthesis

(2009) Sonja Storbeck et al.   FEBS Journal

The Radical SAM Superfamily

(2008) Perry A. Frey et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY