Inhibiting epidermal growth factor receptor signalling potentiates mesenchymal-epithelial transition of breast cancer stem cells and their responsiveness to anticancer drugs

2-Azetidinones: Synthesis and biological evaluation as potential anti-breast cancer agents

(2016) Ramasatyaveni Geesala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Histone deacetylases differentially regulate the proliferative phenotype of mouse bone marrow stromal and hematopoietic stem/progenitor cells

(2016) Neha R. Dhoke et al.   Stem Cell Research

Chemopreventive and therapeutic potential of chrysin in cancer: mechanistic perspectives

(2015) Eshvendar Reddy Kasala et al.   TOXICOLOGY LETTERS

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

(2015) Nicole M. Davis et al.   Oncotarget

Targeting the MUC1-C oncoprotein inhibits self-renewal capacity of breast cancer cells

(2015) Maroof Alam et al.   Oncotarget

Nanoparticles generated by PEG-Chrysin conjugates for efficient anticancer drug delivery

(2014) Hui Zheng et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The cellular thermal shift assay for evaluating drug target interactions in cells

(2014) Rozbeh Jafari et al.   Nature Protocols

Design and synthesis of novel pyrimido[4,5- b ]azepine derivatives as HER2/EGFR dual inhibitors

(2013) Youichi Kawakita et al.   BIOORGANIC & MEDICINAL CHEMISTRY

S-adenosylmethionine limitation induces p38 mitogen-activated protein kinase and triggers cell cycle arrest in G1

(2013) D.-W. Lin et al.   JOURNAL OF CELL SCIENCE

Prolidase Directly Binds and Activates Epidermal Growth Factor Receptor and Stimulates Downstream Signaling

(2012) Lu Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-Nitrosylation of EGFR and Src Activates an Oncogenic Signaling Network in Human Basal-Like Breast Cancer

(2012) C. H. Switzer et al.   MOLECULAR CANCER RESEARCH

Receptor Tyrosine Kinases and Targeted Cancer Therapeutics

(2011) Kenji Takeuchi et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein

(2011) Kathleen Aertgeerts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

(2011) Lauren L.C. Marotta et al.   JOURNAL OF CLINICAL INVESTIGATION

TIEG1 Inhibits Breast Cancer Invasion and Metastasis by Inhibition of Epidermal Growth Factor Receptor (EGFR) Transcription and the EGFR Signaling Pathway

(2011) W. Jin et al.   MOLECULAR AND CELLULAR BIOLOGY

The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer

(2011) L M Privette Vinnedge et al.   ONCOGENE

Triple negative breast cancer - prognostic factors and survival

(2011) Tanja Ovcaricek et al.   Radiology and Oncology

Inhibition of Platelet-Derived Growth Factor Receptor Signaling Regulates Oct4 and Nanog Expression, Cell Shape, and Mesenchymal Stem Cell Potency

(2011) Stephen G. Ball et al.   STEM CELLS

Enhanced antiproliferative and apoptotic response to combined treatment of γ-tocotrienol with erlotinib or gefitinib in mammary tumor cells

(2010) Sunitha V Bachawal et al.   BMC CANCER

Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes

(2010) Mothaffar F. Rimawi et al.   CANCER

Targeting Breast Cancer Stem Cells

(2010) Suling Liu et al.   JOURNAL OF CLINICAL ONCOLOGY

Synthesis and cytotoxicity of novel chrysin derivatives

(2010) Kun Hu et al.   MEDICINAL CHEMISTRY RESEARCH

Silencing Kinase-Interacting Stathmin Gene Enhances Erlotinib Sensitivity by Inhibiting Ser10 p27 Phosphorylation in Epidermal Growth Factor Receptor-Expressing Breast Cancer

(2010) D. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Receptor-Based Virtual Screening of EGFR Kinase Inhibitors from the NCI Diversity Database

(2010) Kiattawee Choowongkomon et al.   MOLECULES

Transforming growth factor-β-induced epithelial–mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression

(2010) M K Wendt et al.   ONCOGENE

Epithelial-Mesenchymal Transition-Derived Cells Exhibit Multilineage Differentiation Potential Similar to Mesenchymal Stem Cells

(2010) Venkata Lokesh Battula et al.   STEM CELLS

Permanently Blocked Stem Cells Derived From Breast Cancer Cell Lines

(2010) Gangadharan B. Sajithlal et al.   STEM CELLS

Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer

(2009) B. Corkery et al.   ANNALS OF ONCOLOGY

The Steroid Receptor Coactivator-1 Regulates Twist Expression and Promotes Breast Cancer Metastasis

(2009) L. Qin et al.   CANCER RESEARCH

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

(2009) E. Charafe-Jauffret et al.   CLINICAL CANCER RESEARCH

Energetic analysis of fragment docking and application to structure-based pharmacophore hypothesis generation

(2009) Kathryn Loving et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN