Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction

Role of carvacrol in cardioprotection against myocardial ischemia/reperfusion injury in rats through activation of MAPK/ERK and Akt/eNOS signaling pathways

(2017) Yunping Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Selective Biological Responses of Phagocytes and Lungs to Purified Histones

(2017) Fatemeh Fattahi et al.   Journal of Innate Immunity

Complement and sepsis-induced heart dysfunction

(2017) Fatemeh Fattahi et al.   MOLECULAR IMMUNOLOGY

Exendin-4 induces myocardial protection through MKK3 and Akt-1 in infarcted hearts

(2016) Jianfeng Du et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis

(2016) Miriam Kalbitz et al.   FASEB JOURNAL

Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro

(2016) Miriam Kalbitz et al.   JOURNAL OF IMMUNOLOGY

A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation

(2016) Xin Liu et al.   Nature Communications

Role of extracellular histones in the cardiomyopathy of sepsis

(2015) Miriam Kalbitz et al.   FASEB JOURNAL

Grb2-associated binder 1 is essential for cardioprotection against ischemia/reperfusion injury

(2014) Lulu Sun et al.   BASIC RESEARCH IN CARDIOLOGY

C5L2 is required for C5a-triggered receptor internalization and ERK signaling

(2014) Wei-Chan Hsu et al.   CELLULAR SIGNALLING

Critical Role for the NLRP3 Inflammasome during Acute Lung Injury

(2014) J. J. Grailer et al.   JOURNAL OF IMMUNOLOGY

Inhibition of 12/15 lipoxygenase by baicalein reduces myocardial ischemia/reperfusion injury via modulation of multiple signaling pathways

(2013) Lina Song et al.   APOPTOSIS

Cardioprotective 3′,4′-dihydroxyflavonol attenuation of JNK and p38MAPKsignalling involves CaMKII inhibition

(2013) Nicholas R. Lim et al.   BIOCHEMICAL JOURNAL

‘State-of-the-heart’ of cardiac laminopathies

(2013) Marie-Elodie Cattin et al.   CURRENT OPINION IN CARDIOLOGY

Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury

(2013) Markus Bosmann et al.   FASEB JOURNAL

Structure- and ligand-based drug design of novel p38-alpha MAPK inhibitors in the fight against the Alzheimer’s disease

(2013) Flávio Roberto Pinsetta et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Pharmacodynamic Effects and Mechanisms of Resistance to Vemurafenib in Patients With Metastatic Melanoma

(2013) Kerstin Trunzer et al.   JOURNAL OF CLINICAL ONCOLOGY

MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway

(2011) Markus Bosmann et al.   FASEB JOURNAL

Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis

(2011) Markus Bosmann et al.   FASEB JOURNAL

Critical role of p38 mitogen-activated protein kinase signaling in septic lung injury*

(2009) Muhammad Asaduzzaman et al.   CRITICAL CARE MEDICINE

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

Functional roles for C5a receptors in sepsis

(2008) Daniel Rittirsch et al.   NATURE MEDICINE