Cardioprotective 3′,4′-dihydroxyflavonol attenuation of JNK and p38MAPKsignalling involves CaMKII inhibition

Involvement of ASK1–p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion

(2013) Kiyoshi Yamaguchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

CaMKII Activates ASK1 to Induce Apoptosis of Spinal Astrocytes Under Oxygen–Glucose Deprivation

(2013) Gang Liu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Calmodulin-Dependent Protein Kinase II: Linking Heart Failure and Arrhythmias

(2012) Paari Dominic Swaminathan et al.   CIRCULATION RESEARCH

CaMKII determines mitochondrial stress responses in heart

(2012) Mei-ling A. Joiner et al.   NATURE

Cardioprotection from ischaemia–reperfusion injury by a novel flavonol that reduces activation of p38 MAPK

(2011) Colleen J. Thomas et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ca2+/calmodulin-dependent protein kinase inhibition suppresses post-ischemic arrhythmogenesis and mediates sinus bradycardic recovery in reperfusion

(2011) James R. Bell et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

CaMKII in myocardial hypertrophy and heart failure

(2011) Mark E. Anderson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

(2011) Theonie Anastassiadis et al.   NATURE BIOTECHNOLOGY

Water soluble flavonol prodrugs that protect against ischaemia-reperfusion injury in rat hindlimb and sheep heart

(2011) Spencer J. Williams et al.   MedChemComm

Reperfusion Injury Salvage Kinase and Survivor Activating Factor Enhancement Prosurvival Signaling Pathways in Ischemic Postconditioning: Two Sides of the Same Coin

(2010) Derek J. Hausenloy et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Biological Evaluation and Structural Determinants of p38α Mitogen-Activated-Protein Kinase and c-Jun-N-Terminal Kinase 3 Inhibition by Flavonoids

(2010) Márcia Goettert et al.   CHEMBIOCHEM

The phosphatidylinositol 3-kinase-Akt pathway protects cardiomyocytes from ischaemic and hypoxic apoptosis via mitochondrial function

(2010) Hua-Pei Song et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

c-Jun N-terminal Kinase Phosphorylation of Stathmin Confers Protection against Cellular Stress

(2010) Dominic C. H. Ng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitogen-Activated Protein Kinase Signaling in the Heart: Angels Versus Demons in a Heart-Breaking Tale

(2010) Beth A. Rose et al.   PHYSIOLOGICAL REVIEWS

3′,4′-Dihydroxyflavonol down-regulates monocyte chemoattractant protein-1 in smooth muscle: role of focal adhesion kinase and PDGF receptor signalling

(2009) F Jiang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reduction of infarct size by gentle reperfusion without activation of reperfusion injury salvage kinases in pigs

(2009) J. Musiolik et al.   CARDIOVASCULAR RESEARCH

Angiotensin II–Induced Oxidative Stress Resets the Ca 2+ Dependence of Ca 2+ –Calmodulin Protein Kinase II and Promotes a Death Pathway Conserved Across Different Species

(2009) Julieta Palomeque et al.   CIRCULATION RESEARCH

ASK1 Regulates Cardiomyocyte Death but Not Hypertrophy in Transgenic Mice

(2009) Qinghang Liu et al.   CIRCULATION RESEARCH

3′,4′-Dihydroxyflavonol improves post-ischaemic coronary endothelial function following 7days reperfusion in sheep

(2009) Sheng Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

(2008) Jeffrey R. Erickson et al.   CELL

Discovery of Water-Soluble Antioxidant Flavonols without Vasorelaxant Activity

(2008) Suwan Yap et al.   ChemMedChem

CaMKII and Its Role in Cardiac Arrhythmia

(2008) JEFFREY R. ERICKSON et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Protein Kinases in Organ Ischemia and Reperfusion

(2008) Luis H. Toledo-Pereyra et al.   JOURNAL OF INVESTIGATIVE SURGERY

Understanding the Cardioprotective Effects of Flavonols: Discovery of Relaxant Flavonols without Antioxidant Activity

(2008) Cheng Xue Qin et al.   JOURNAL OF MEDICINAL CHEMISTRY

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY