Extranuclear partners of androgen receptor: at the crossroads of proliferation, migration, and neuritogenesis

Alzheimer's Disease-Linked Presenilin Mutation (PS1M146L) Induces Filamin Expression and γ-Secretase Independent Redistribution

(2017) Qun Lu et al.   JOURNAL OF ALZHEIMERS DISEASE

Androgen Deprivation Therapy and Future Alzheimer’s Disease Risk

(2016) Kevin T. Nead et al.   JOURNAL OF CLINICAL ONCOLOGY

Recent progress in the development of protein–protein interaction inhibitors targeting androgen receptor–coactivator binding in prostate cancer

(2016) Eric Biron et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Taxane Chemotherapy for Hormone-Naïve Prostate Cancer with Its Expanding Role as Breakthrough Strategy

(2016) Masaki Shiota et al.   Frontiers in Oncology

Targeted treatment of metastatic castration-resistant prostate cancer with sipuleucel-T immunotherapy

(2015) Peter F. Mulders et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Discovery and Optimization of a Novel Series of Dyrk1B Kinase Inhibitors To Explore a MEK Resistance Hypothesis

(2015) Jason G. Kettle et al.   JOURNAL OF MEDICINAL CHEMISTRY

Amyloid β-abrogated TrkA ubiquitination in PC12 cells analogous to Alzheimer's disease

(2015) Chen Zheng et al.   JOURNAL OF NEUROCHEMISTRY

Cross-talk between androgen receptor/filamin A and TrkA regulates neurite outgrowth in PC12 cells

(2015) Marzia Di Donato et al.   MOLECULAR BIOLOGY OF THE CELL

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Genomic landscapes of breast fibroepithelial tumors

(2015) Jing Tan et al.   NATURE GENETICS

Androgen receptor non-nuclear regulation of prostate cancer cell invasion mediated by Src and matriptase

(2015) Jelani C. Zarif et al.   Oncotarget

Enfermedad de Kennedy y resistencia parcial androgénica. Descripción de 4 casos y revisión de la literatura

(2015) Rocío Valera Yepes et al.   Endocrinologia y Nutricion

Src signaling pathways in prostate cancer

(2014) Andreas Varkaris et al.   CANCER AND METASTASIS REVIEWS

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

(2014) Emmanuel S. Antonarakis et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Form of the Metabolic Syndrome Associated with Mutations in DYRK1B

(2014) Ali R. Keramati et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of non-genomic androgen signalling in suppressing proliferation of fibroblasts and fibrosarcoma cells

(2014) G Castoria et al.   Cell Death & Disease

Fyn kinase inhibition as a novel therapy for Alzheimer’s disease

(2014) Haakon B Nygaard et al.   Alzheimers Research & Therapy

Plasma DYRK1A as a novel risk factor for Alzheimer’s disease

(2014) N Janel et al.   Translational Psychiatry

Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance

(2013) Irina Lonskaya et al.   EMBO Molecular Medicine

The dual role of filamin A in cancer: can't live with (too much of) it, can't live without it

(2013) Rosalinda M Savoy et al.   ENDOCRINE-RELATED CANCER

A Truncated Fragment of Src Protein Kinase Generated by Calpain-mediated Cleavage Is a Mediator of Neuronal Death in Excitotoxicity

(2013) M. Iqbal Hossain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver

(2013) C Chang et al.   ONCOGENE

Targeting Androgen Receptor/Src Complex Impairs the Aggressive Phenotype of Human Fibrosarcoma Cells

(2013) Gabriella Castoria et al.   PLoS One

Direct Interaction between AR and PAK6 in Androgen-Stimulated PAK6 Activation

(2013) Xia Liu et al.   PLoS One

Inhibition of androgen receptor and  -catenin activity in prostate cancer

(2013) E. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression profiles and functional associations of endogenous androgen receptor and caveolin-1 in prostate cancer cell lines

(2013) Nigel C. Bennett et al.   PROSTATE

Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control

(2012) Walter Becker   CELL CYCLE

Activation of rapid oestrogen signalling in aggressive human breast cancers

(2012) Coralie Poulard et al.   EMBO Molecular Medicine

Reducing Amyloid-Related Alzheimer's Disease Pathogenesis by a Small Molecule Targeting Filamin A

(2012) H.-Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Filamin A Regulates Neural Progenitor Proliferation and Cortical Size through Wee1-Dependent Cdk1 Phosphorylation

(2012) G. Lian et al.   JOURNAL OF NEUROSCIENCE

Central Role for PELP1 in Nonandrogenic Activation of the Androgen Receptor in Prostate Cancer

(2012) Lin Yang et al.   MOLECULAR ENDOCRINOLOGY

Tyrosine phosphorylation of estradiol receptor by Src regulates its hormone-dependent nuclear export and cell cycle progression in breast cancer cells

(2012) G Castoria et al.   ONCOGENE

Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A Association

(2011) Gabriella Castoria et al.   PLoS One

The filamins

(2011) Fumihiko Nakamura et al.   Cell Adhesion & Migration

Nerve Growth Factor in Cancer Cell Death and Survival

(2011) Niamh Molloy et al.   Cancers

Role of targeted therapy in the treatment of advanced prostate cancer

(2010) Karim Fizazi et al.   BJU INTERNATIONAL

Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains

(2010) Sébastien Feuillette et al.   BRAIN RESEARCH

Invasive Prostate Carcinoma Driven by c-Src and Androgen Receptor Synergy

(2010) H. Cai et al.   CANCER RESEARCH

DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles

(2010) Sergi Aranda et al.   FASEB JOURNAL

Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells

(2010) O. Yabut et al.   JOURNAL OF NEUROSCIENCE

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS

(2010) Matthias Lauth et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SRC kinase inhibition: Targeting bone metastases and tumor growth in prostate and breast cancer

(2009) Fred Saad et al.   CANCER TREATMENT REVIEWS

Nuclear versus Cytoplasmic Localization of Filamin A in Prostate Cancer: Immunohistochemical Correlation with Metastases

(2009) R. G. Bedolla et al.   CLINICAL CANCER RESEARCH

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

Testosterone deficiency, insulin resistance and the metabolic syndrome

(2009) Michael Zitzmann   Nature Reviews Endocrinology

Targeting Src Family Kinases Inhibits Growth and Lymph Node Metastases of Prostate Cancer in an Orthotopic Nude Mouse Model

(2008) S. I. Park et al.   CANCER RESEARCH

Androgen regulation of axon growth and neurite extension in motoneurons

(2008) Keith N. Fargo et al.   HORMONES AND BEHAVIOR

p21-activated Kinase-aberrant Activation and Translocation in Alzheimer Disease Pathogenesis

(2008) Qiu-Lan Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-genomic actions of androgens

(2007) C.D. Foradori et al.   FRONTIERS IN NEUROENDOCRINOLOGY